Aristocort

Macular Edema, Stomatitis, Denture, Ophthalmia, Sympathetic + 113 more

Treatment

16 FDA approvals

20 Active Studies for Aristocort

Treatment for

Macular Edema

What is Aristocort

Triamcinolone

The Generic name of this drug

Treatment Summary

Triamcinolone is a steroid used to treat various types of inflammation, from allergies to multiple sclerosis. It can be used as a one-time treatment for knee pain related to arthritis, or as a topical treatment for skin conditions. There are several forms of triamcinolone, including hexacetonide, acetonide, and diacetate. Triamcinolone was approved by the FDA in 1957, and in 2021 a suspension of triamcinolone acetonide was approved for suprachoroidal injection to treat macular edema associated with uveitis.

Aristocort

is the brand name

image of different drug pills on a surface

Aristocort Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Aristocort

Triamcinolone

1961

532

Approved as Treatment by the FDA

Triamcinolone, also called Aristocort, is approved by the FDA for 16 uses which include Lichen Planus and Ganglia .

Lichen Planus

Helps manage Lichen Planus (LP)

Ganglia

Helps manage cystic tumour of the ganglia

Granuloma Annulare

Helps manage granuloma annulare lesions

Psoriasis

Helps manage Psoriatic plaque

Neurodermatitis

Helps manage Lichen simplex chronicus

Lupus Erythematosus, Discoid

Helps manage Discoid Lupus Erythematosus (DLE)

cystic tumour of the ganglia

Helps manage cystic tumour of the ganglia

granuloma annulare lesions

Helps manage granuloma annulare lesions

Lichen Planus (LP)

Helps manage Lichen Planus (LP)

Psoriatic plaque

Helps manage Psoriatic plaque

Discoid Lupus Erythematosus (DLE)

Helps manage Discoid Lupus Erythematosus (DLE)

Necrobiosis Lipoidica

Helps manage Necrobiosis lipoidica diabeticorum

Alopecia Areata

Helps manage Alopecia Areata (AA)

Alopecia Areata (AA)

Helps manage Alopecia Areata (AA)

Lichen simplex chronicus

Helps manage Lichen simplex chronicus

Keloids Scars

Helps manage Keloids Scars

Effectiveness

How Aristocort Affects Patients

Triamcinolone is a type of medication which reduces inflammation in many areas of the body. It should not be injected directly into the spine.

How Aristocort works in the body

Triamcinolone helps reduce inflammation. It does this by limiting the breakdown of cell membranes which prevents the formation of certain acids. These acids are responsible for producing signals that cause inflammation. Triamcinolone also helps by making blood vessels less wide, and reducing the number of cells that flow to sites of inflammation.

When to interrupt dosage

The advised portion of Aristocort is contingent upon the determined condition, including Mycosis Fungoides (MF), Mycoses and Alopecia Areata (AA). The amount of dosage fluctuates as per the technique of delivery (e.g. Ointment or Injection, suspension - Intralesional; Parenteral) featured in the table beneath.

Condition

Dosage

Administration

Macular Edema

, 40.0 mg/mL, 10.0 mg/mL, 0.055 mg, 0.001 mg/mg, 0.25 mg/mL, 1.0 mg/mL, 0.0005 mg/mg, 0.00025 mg/mg, 0.005 mg/mg, 5.0 mg/mL, 20.0 mg/mL, 0.000147 mg/mg, 0.5 mg/mL, 40.0 mg, 1.0 mg, 0.000025 mg/mg, 0.1 %, 0.025 %, 5.0 mg, 0.25 mg, 2.0 mg, 4.0 mg, 0.5 %, 15.0 mg/mL, 6.5 mg, 80.0 mg/mL, 0.075 mg, 200.0 mg/mL, 32.0 mg, 0.055 mg/dose, 0.5 mg, 0.2 mg/pump actuation, 0.1 mg/dose, 25.0 mg/mL, 0.055 mg/pump actuation, 2.0 mg/mL, 0.4 mg/mL

Injection, suspension, Intra-articular; Intramuscular, Injection, suspension - Intra-articular; Intramuscular, , Injection, suspension - Intra-articular; Intralesional, Intra-articular; Intralesional, Cream - Topical, Topical, Ointment - Topical, Lotion - Topical, Lotion, Cream, Ointment, Intralesional; Parenteral, Injection, suspension - Intralesional; Parenteral, Intra-articular; Parenteral, Injection, suspension - Intra-articular; Parenteral, Intra-articular; Intrabursal; Intradermal; Intralesional, Injection, suspension - Intra-articular; Intrabursal; Intradermal; Intralesional, Aerosol, spray, Aerosol, spray - Topical, Paste - Topical, Paste, Spray, metered - Nasal, Nasal, Spray, metered, Injection, suspension - Intramuscular, Intramuscular, Dental, Paste - Dental, Suspension - Intra-articular; Intramuscular, Suspension - Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension, Intra-articular; Intrabursal; Intramuscular, Respiratory (inhalation), Oral, Tablet, Tablet - Oral, Intra-articular; Intramuscular; Intrasynovial, Liquid - Intra-articular; Intramuscular; Intrasynovial, Intra-articular; Intradermal; Intramuscular, Syrup - Oral, Syrup, Suspension - Intramuscular, Liquid - Intra-articular; Intradermal; Intramuscular, Intra-articular; Intradermal; Intralesional; Intramuscular, Suspension - Intra-articular; Intradermal; Intralesional; Intramuscular, Spray, suspension - Nasal, Injection, solution, Injection, solution - Intra-articular; Intramuscular, Kit, Kit - Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Ophthalmic, Injection, suspension - Ophthalmic, Suspension - Intravitreal, Intravitreal, Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Kit - Infiltration; Intra-articular; Intramuscular; Respiratory (inhalation); Topical, Intra-articular, Suspension - Intra-articular, Spray - Topical, Spray, Intra-articular; Intrabursal; Intradermal; Intrasynovial, Suspension - Intra-articular; Intrabursal; Intramuscular, Intralesional, Suspension - Intralesional, Aerosol, metered - Nasal, Aerosol, metered, Aerosol, metered - Respiratory (inhalation), Liquid, Epidural; Infiltration; Intra-articular; Intramuscular; Topical, Intra-articular; Intrasynovial; Periarticular, Suspension - Intra-articular; Intrasynovial; Periarticular, Kit - Intra-articular; Intramuscular, Suspension - Ophthalmic, Implant, Kit - Epidural; Infiltration; Intra-articular; Intramuscular, Epidural; Infiltration; Intra-articular; Intramuscular, Epidural; Intra-articular; Intramuscular; Topical, Kit - Epidural; Intra-articular; Intramuscular; Topical, Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Intrasynovial; Parenteral, Kit - Intra-articular, Paste, dentifrice, Paste, dentifrice - Dental, Ointment - Buccal, Buccal, Subcutaneous, Implant - Subcutaneous, Injection, suspension - Intra-articular; Intramuscular; Intravitreal, Intra-articular; Intramuscular; Intravitreal, Epidural; Infiltration; Intra-articular; Intralesional, Kit - Epidural; Infiltration; Intra-articular; Intralesional, Infiltration; Soft tissue; Topical, Kit - Infiltration; Soft tissue; Topical, Emulsion, Gel, Emulsion - Topical, Kit - Topical, Intra-articular; Intramuscular; Topical, Injection, suspension - Intra-articular, Infiltration; Intra-articular; Intramuscular; Topical, Kit - Infiltration; Intra-articular; Intramuscular; Topical, Gel - Topical

Neurodermatitis

Pericarditis

cutaneous candidiasis

Wound Infection

Lupus Erythematosus, Discoid

Ankylosing Spondylitis

Eczema

Stomatitis

Keloids Scars

Nummular Dermatitis

Skin

Stomatitis, Denture

Ophthalmia, Sympathetic

Hypercalcemia

Stomatitis, Aphthous

Multiple Sclerosis

Inflammation

Hives

Berylliosis

Warnings

Aristocort has four contraindications. It should not be taken in case of any of the conditions found in the table below.

Aristocort Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Triamcinolone may interact with Pulse Frequency

Mycoses

Do Not Combine

active periocular infections

Do Not Combine

Eye Infections

Do Not Combine

There are 20 known major drug interactions with Aristocort.

Common Aristocort Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Triamcinolone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Triamcinolone is combined with Abetimus.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be increased when combined with Triamcinolone.

Aristocort Toxicity & Overdose Risk

The lowest toxic dose of triamcinolone acetonide for rats is 13,100µg/kg and 132mg/kg for mice. In rats, the lowest toxic dose is 1451mg/kg and 2168mg/kg in mice. When administered through the abdomen, the lowest toxic dose is 105mg/kg in mice. Those who overdose on triamcinolone acetonide may develop Cushing's syndrome, which can be treated with supportive therapy and mifepristone.

Aristocort Novel Uses: Which Conditions Have a Clinical Trial Featuring Aristocort?

Currently, 1076 active trials are examining the potential of Aristocort to provide relief from Lupus, Atopic Dermatitis and Brain Metastases.

Condition

Clinical Trials

Trial Phases

Synovitis

1 Actively Recruiting

Phase 4

Lupus

63 Actively Recruiting

Phase 2, Phase 1, Phase 3, Not Applicable, Phase 4, Early Phase 1

Crohn's Disease

58 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Phase 3, Phase 4, Early Phase 1

Erythema Multiforme

0 Actively Recruiting

Asthma

97 Actively Recruiting

Phase 1, Phase 4, Not Applicable, Early Phase 1, Phase 2, Phase 3

Vitrectomy therapy

0 Actively Recruiting

Dermatitis, Seborrheic

0 Actively Recruiting

Rheumatoid Arthritis

63 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Macular Edema

4 Actively Recruiting

Phase 2, Not Applicable, Phase 3

Thyroiditis

0 Actively Recruiting

Brain

2 Actively Recruiting

Not Applicable

Stomatitis

0 Actively Recruiting

Dermatitis

0 Actively Recruiting

Tinea

0 Actively Recruiting

Conjunctivitis, Bacterial

0 Actively Recruiting

Tenosynovitis

0 Actively Recruiting

Mycoses

0 Actively Recruiting

Dermatitis, Allergic Contact

0 Actively Recruiting

Cellulitis

0 Actively Recruiting

Lupus Erythematosus

3 Actively Recruiting

Phase 4, Phase 1, Not Applicable

Aristocort Reviews: What are patients saying about Aristocort?

Patient Review

1/17/2009

Aristocort for Rash

This treatment helps me a lot with my sweating and rashes. I'm really prone to getting pimples on my backside, but this cream takes care of it quickly.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about aristocort

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take for ARISTOCORT to work?

"This medication contains a topical anti-inflammatory drug from the corticosteroid family. It typically reduces inflammation and itching. Several days of treatment may be required to see the full effect."

Answered by AI

How does ARISTOCORT work in the body?

"Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here.

This medication is used to treat irritated skin, including conditions like psoriasis and eczema. It may also help with itchiness. The medication works by reducing swelling and inflammation of the skin. This medication is available in different forms and brand names. The specific brand may not be available for all the conditions discussed."

Answered by AI

Is ARISTOCORT a hydrocortisone?

"ARISTOCORT is a corticosteroid that comes in the form of a cream or ointment."

Answered by AI

What is ARISTOCORT cream used for?

"This medication is used to reduce the swelling, itching, and redness that can occur in a variety of skin conditions, such as eczema, dermatitis, allergies, and rash. It is a medium- to strong-potency corticosteroid."

Answered by AI