40 Participants NeededMy employer runs this trial

Fruit Juice for Inflammation

BG
AG
Overseen ByAshley Giannita, BS, CCRC
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Northwell Health
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

Dietary patterns and physical inactivity common in Western societies have been associated with chronic low-grade inflammation and an increased risk of non-communicable health conditions. Fruits and vegetables contain polyphenols and other bioactive compounds that may have antioxidant and anti-inflammatory properties and may influence inflammatory biomarkers.

This study will evaluate the effects of increased consumption of a fruit juice on inflammatory biomarkers and exercise capacity in adults with mildly elevated inflammation. Approximately 40 participants will be randomly assigned to consume one of two fruit juice interventions daily for approximately 2 weeks. Changes in C-reactive protein (CRP) and exercise capacity, assessed using a 6-minute walk test, will be evaluated before and after the intervention and compared between the two groups.

Who Is on the Research Team?

CT

Christopher Tanayan, MD

Principal Investigator

Northwell Health

Are You a Good Fit for This Trial?

This trial is for adults with mildly elevated inflammation levels. Participants should generally be healthy but have higher-than-normal markers of inflammation in their blood.

Inclusion Criteria

Prior confirmed high normal or mild elevation of CRP (1.5-9.9 mg/L)
I am between 18 and 65 years old.
Willing to consume 2-8 oz juice beverages per day, containing 25 grams of sugar each, for 2 weeks
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Exclusion Criteria

Known allergy to apples or cherries
Pregnancy or planning pregnancy during the duration of the study
Score of 4 on any question in the DePaul Symptom Questionnaire - Post Exertional Malaise (DSQ-PEM)
See 16 more

What Are the Treatments Tested in This Trial?

Trial Overview

The study tests whether drinking more fruit juice affects exercise ability and inflammation. About 40 people will be randomly assigned to drink one of two types of fruit juice daily for about 2 weeks, then have their fitness and blood markers checked.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Active Fruit Juice InterventionExperimental Treatment1 Intervention
Group II: Control Fruit Juice InterventionActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Northwell Health

Lead Sponsor

Trials
481
Recruited
470,000+