Dovonex

Q: Is Dovonex cream a steroid?

<p>Calcipotriene is a form of <a href="https://www.withpower.com/clinical-trials/vitamin-d">vitamin d</a>, but it is not considered a steroid medication.</p>

Psoriasis, Psoriasis Vulgaris

Treatment

20 Active Studies for Dovonex

Treatment for

Psoriasis

What is Dovonex

Calcipotriol

The Generic name of this drug

Treatment Summary

Calcipotriol is a synthetic form of Vitamin D used to treat skin conditions.

Calcipotriene

is the brand name

image of different drug pills on a surface

Dovonex Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Calcipotriene

Calcipotriol

1996

Effectiveness

How Dovonex Affects Patients

Calcipotriene is a form of Vitamin D that is made synthetically. Normally, the body obtains Vitamin D from exposure to the sun's ultraviolet rays, which turns a substance in skin (7-dehydrocholesterol) into Vitamin D3 (cholecalciferol).

How Dovonex works in the body

We don't fully understand how calcipotriol works to treat psoriasis, but we know that it binds to the Vitamin D receptor in cells, like T cells of the immune system. This binding process changes gene expression in the cells, which can lead to slower cell growth and change the way cells work.

When to interrupt dosage

The recommended quantity of Dovonex is contingent upon the diagnosed circumstance. The amount diverges depending on the method of application featured in the table underneath.

Condition

Dosage

Administration

Psoriasis

, 0.05 mg/mL, 0.00005 mg/mg

Solution, Solution - Topical, , Topical, Ointment - Topical, Cream - Topical, Cream, Ointment, Spray, metered, Spray, metered - Topical, Suspension, Suspension - Topical, Aerosol, foam - Topical, Aerosol, foam, Kit, Kit - Topical, Gel, Gel - Topical

Psoriasis Vulgaris

, 0.05 mg/mL, 0.00005 mg/mg

Warnings

Dovonex Contraindications

Condition

Risk Level

Notes

Hypercalcemia

Do Not Combine

vitamin D intoxication

Do Not Combine

Facial Paralysis

Do Not Combine

There are 15 known major drug interactions with Dovonex.

Common Dovonex Drug Interactions

Drug Name

Risk Level

Description

Calcium

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium.

Calcium Phosphate

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium Phosphate.

Calcium acetate

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium acetate.

Calcium carbonate

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium carbonate.

Calcium cation

Moderate

The risk or severity of adverse effects can be increased when Calcipotriol is combined with Calcium cation.

Dovonex Toxicity & Overdose Risk

Applying calcipotriene to the skin can cause it to enter the bloodstream, which can lead to elevated calcium levels if too much is used.

image of a doctor in a lab doing drug, clinical research

Dovonex Novel Uses: Which Conditions Have a Clinical Trial Featuring Dovonex?

18 clinical trials are presently underway to determine the effectiveness of Dovonex in the management of Plaque Psoriasis.

Condition

Clinical Trials

Trial Phases

Psoriasis

0 Actively Recruiting

Psoriasis Vulgaris

22 Actively Recruiting

Early Phase 1, Phase 3, Phase 4, Phase 2, Not Applicable

Dovonex Reviews: What are patients saying about Dovonex?

Patient Review

8/22/2010

Dovonex for Psoriasis of Scalp

Dovonex is effective, but I wish it weren't quite so expensive.

4.7

Patient Review

4/6/2011

Dovonex for Plaque Psoriasis

Worked quite well for me. Not sure why people are complaining about the price; it's been available as a generic for a while now.

4.3

Patient Review

12/25/2009

Dovonex for Plaque Psoriasis

I've had psoriasis for a decade now, and I've tried a lot of different creams. They never really worked well, and they would always end up staining my clothes and bedding. Doxonex has been much better; after using it for six months, the redness and scales have improved significantly. It's not a cure-all by any means—psoriasis flare-ups are still common—but this is the best drug preparation I've found so far.

Patient Review

8/21/2009

Dovonex for Plaque Psoriasis

I've been using Morphia and Dovonex for close to a year now, and while it's helped make the skin in that area smoother, it's only temporary (about three hours) and very expensive (I have to pay nearly $500 per tube every two months).

Patient Review

4/14/2010

Dovonex for Plaque Psoriasis

The combination of this medication with a steroid has helped my flare-up after only two weeks. However, I was not expecting how expensive this would be--it's by far the most costly drug I've ever taken for my psoriasis (which, by the way, I've had for 56 years). Thankfully, my insurance covered most of the cost.

Patient Review

2/1/2010

Dovonex for Plaque Psoriasis

I originally got this from somebody in South America, not sure if it was available here yet. Worked well on certain spots of the body (back, legs, elbows, ear, scalp). Tried it on the spots I get on my fingers and it doesn't do much but keeps them a little lubricated (probably the mineral oil). The best combo I've used has been Dovonex for spot treatment and Clobex/Talconex for tough spots.

Patient Review

5/31/2011

Dovonex for Plaque Psoriasis

The quality of the tube cap is terrible. I have used 2 tubes, both of the caps broken.

3.7

Patient Review

9/3/2010

Dovonex for Psoriasis of Scalp

I've been using this medication for two weeks and it's helped a lot so far. I use it one to two times a day, as needed. Fingers crossed that it keeps working!

3.7

Patient Review

7/19/2015

Dovonex for Plaque Psoriasis

This cream helps with the build-up of my mild psoriasis on my elbows and knees, but unfortunately doesn't do anything for the redness.

Patient Review

12/25/2008

Dovonex for Psoriasis of Scalp

I've had psoriasis for five years and this was the first treatment that showed any real promise. It did work for a little while, but then my symptoms flared up again when winter came.

Patient Review

1/28/2022

Dovonex for Plaque Psoriasis

Yes, this definitely helps. Not a miracle worker by any means, but it does help. The price is pretty high though; even in Canada it's about $165 per tube.

2.7

Patient Review

1/6/2009

Dovonex for Psoriasis of Scalp

Dovenex cream for the scalp is effective, but Dovenex cream for other areas of the body are ineffective.

1.7

Patient Review

12/7/2013

Dovonex for Plaque Psoriasis

I found this treatment to be largely ineffective against my psoriasis. It was also quite expensive, at close to $1000 per tube. I stopped using it and started juicing fruits and vegetables instead; now, I don't have any psoriasis symptoms at all. If I had known this earlier, it would have saved me a lot of suffering.

1.7

Patient Review

12/3/2008

Dovonex for Plaque Psoriasis

Patient Review

10/21/2008

Dovonex for Plaque Psoriasis

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about dovonex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Dovonex need a prescription?

"The Medicines and Healthcare products Regulatory Agency (MHRA) has approved the sale of Dovonex psoriasis ointment (50mg/g) without a prescription. The ointment will be available through pharmacies."

Answered by AI

What is Dovonex ointment used for?

"Apply a thin layer of ointment to the affected area and rub in gently.

The following text is about a ointment that is indicated for the topical treatment of plaque psoriasis. The ointment should be applied to the affected area once or twice daily, and for maximum benefit, it should be used twice daily. To use it, apply a thin layer of the ointment to theaffected area and rub it in gently."

Answered by AI

Is Dovonex cream a steroid?

"Calcipotriene is a form of vitamin d, but it is not considered a steroid medication."

Answered by AI

Is Dovonex a vitamin D?

"Dovonex is a man-made form of vitamin d that is used to treat plaque psoriasis. It may also be used for purposes not listed in this medication guide."

Answered by AI