Desoximetasone

Skin Diseases, Dermatitis, Allergic Contact, Psoriasis Vulgaris + 1 more

Treatment

20 Active Studies for Desoximetasone

Treatment for

Skin Diseases

What is Desoximetasone

Desoximetasone

The Generic name of this drug

Treatment Summary

Glucocorticoids are a type of topical anti-inflammatory medication used to treat skin conditions such as dermatitis, allergies, and psoriasis.

Desoximetasone

is the brand name

Desoximetasone Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Desoximetasone

1985

Effectiveness

How Desoximetasone Affects Patients

Desoximetasone is a type of medication that helps reduce inflammation and itching when applied to the skin. It is a strong topical corticosteroid and should not be used with any type of bandage or covering. Treatment with desoximetasone should not last longer than two weeks, and should be stopped once the desired results have been achieved.

How Desoximetasone works in the body

Topical steroids work to reduce inflammation, but the exact way they do this is not known. It is believed that steroids act by stimulating the production of proteins that block the release of arachidonic acid, a precursor to inflammation-causing molecules like prostaglandins and leukotrienes. Steroids also bind to glucocorticoid receptors, which then travel to the nucleus and bind to DNA to start the production of these proteins.

When to interrupt dosage

The advocated dose of Desoximetasone is contingent upon the determined condition, including Atopic Dermatitis, corticosteroid-responsive dermatoses and Psoriasis. The amount of dosage fluctuates as per the technique of delivery (e.g. Topical or Cream - Topical) mentioned in the following table.

Condition

Dosage

Administration

Skin Diseases

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion, Emulsion - Topical

Psoriasis Vulgaris

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion, Emulsion - Topical

Psoriasis

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion, Emulsion - Topical

Dermatitis, Allergic Contact

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion, Emulsion - Topical

Warnings

There are 20 known major drug interactions with Desoximetasone.

Common Desoximetasone Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abatacept.

Abetimus

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abetimus.

Acteoside

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with Acteoside.

Desoximetasone Toxicity & Overdose Risk

Too much desoximetasone applied to the skin can be absorbed and cause systemic effects. Overdosing on this drug may lead to thinning of the skin and reduced ability of the adrenal cortex to respond to stress.

image of a doctor in a lab doing drug, clinical research

Desoximetasone Novel Uses: Which Conditions Have a Clinical Trial Featuring Desoximetasone?

88 active trials are presently evaluating the potential of Desoximetasone to mitigate the symptoms of Psoriasis, Atopic Dermatitis and Plaque Psoriasis.

Condition

Clinical Trials

Trial Phases

Dermatitis, Allergic Contact

0 Actively Recruiting

Skin Diseases

0 Actively Recruiting

Psoriasis Vulgaris

22 Actively Recruiting

Early Phase 1, Phase 3, Phase 4, Phase 2, Not Applicable

Psoriasis

0 Actively Recruiting

Desoximetasone Reviews: What are patients saying about Desoximetasone?

Patient Review

4/30/2011

Desoximetasone for Skin Condition

This medication quickly and effectively removed the redness on my legs. The only downside is that now my leg hair is growing back very rapidly!

Patient Review

12/20/2017

Desoximetasone for Inflammation of Skin caused by an Allergy

This was the only medication that addressed my son's eczema. We've used it, off and on, for the past five years as needed. I find that I need to use less than what is prescribed; my son has been using it for so long now that his body may be resistant to it. He is currently taking Fluticasone. This medicine provided much-needed relief from the constant itching all over his body for those five years. Let's hope the new prescription will work just as well!

Patient Review

9/6/2016

Desoximetasone for Atopic Dermatitis

We've tried a lot of different treatments for my son's dermatitis, and this is by far the best one. A couple days of application is all it takes to make the symptoms disappear.

Patient Review

11/19/2017

Desoximetasone for Contact Dermatitis

This medication doesn't have propylene glycol, which is great because other topical creams/ointments I've used that did contain it made my skin condition worse. Topicort helped immediately and now I only use it as needed.

Patient Review

1/26/2011

Desoximetasone for Skin Rash that Becomes Thick & Discolored From Rubbing It

This medication is great for occasional poison ivy and oak outbreaks. It relieves itching and prevents the rash from spreading. I also use it with Tecnu poison ivy and oak oil remover soap, which works really well!

Patient Review

4/26/2010

Desoximetasone for Contact Dermatitis

This treatment really helped me. I'm grateful for modern medicine.

Patient Review

4/15/2011

Desoximetasone for Rash

Used it for clearing up Canker Sores. Worked well and quickly.

Patient Review

10/28/2018

Desoximetasone for Atopic Dermatitis

I had a nasty rash that was both itchy and burning. It was on my lower back, both sides of my knees, the back of my forearms, back of my neck, under my shoulder straps etc After 7 months of no relief, I was given DESOXIMETASONE and it works!

4.7

Patient Review

7/11/2010

Desoximetasone for Atopic Dermatitis

This medicine was highly effective in treating my eczema; however, I developed stretch marks as an unfortunate side effect. These are now permanent reminders of the period of my life when I had to deal with eczema.

4.7

Patient Review

4/15/2010

Desoximetasone for Contact Dermatitis

Patient Review

8/27/2013

Desoximetasone for Skin Condition

I could tell a difference within just a few days of taking this medication. My itching improved and I was able to sleep better at night, which was a huge relief. Overall, I'm very pleased with the results.

Patient Review

8/2/2010

Desoximetasone for Reddish Nodules Arranged in a Circle On the Skin

I was very hesitant to use this treatment after reading some reviews, but I'm glad that I did. Within 24 hours, my poison ivy rash was almost gone. This medicine is extremely effective and I have had no side effects.

3.7

Patient Review

6/15/2022

Desoximetasone for Atopic Dermatitis

I've used this cream around 20 times and have found that the tube gets punctured from the sides when you try to squeeze it from the bottom. This happens after a few uses, when there's some space in the tube. I think the material used to make the tube packing is not good quality. I raised this issue with the manufacturer of this drug and provided them with a sample tube for quality control, but they haven't responded. I also contacted FDA but no answer.

Patient Review

6/11/2011

Desoximetasone for Reddish Nodules Arranged in a Circle On the Skin

I've had this disease for a long time, and it's gotten pretty bad. That said, I don't think this cream is very effective because it takes a while to absorb.

Patient Review

3/16/2010

Desoximetasone for Osteoporosis

Patient Review

3/16/2010

Desoximetasone for Atopic Dermatitis

Patient Review

2/8/2013

Desoximetasone for Atopic Dermatitis

I have not found this topical to be effective. If anything, my condition has only gotten worse since using it.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about desoximetasone

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is desoximetasone a strong steroid?

"Desoximetasone is one of the strongest topical steroid medications, though it is not as strong as the spray. The strongest steroid creams, according to the National Psoriasis Foundation, include clobetasol, halobetasol, or fluocinonide."

Answered by AI

What is desoximetasone cream used for?

"Desoximetasone topical is a corticosteroid medication used to relieve redness, itching, swelling, or other discomfort caused by skin conditions. It is available as a cream, ointment, or spray. Desoximetasone topical spray is specifically approved for the treatment of plaque psoriasis."

Answered by AI