Topicort

Q: What is Topicort used to treat?

<p>This medication is used to treat conditions such as <a href="https://www.withpower.com/clinical-trials/eczema">eczema</a>, dermatitis, allergies, and rash by reducing swelling, itching, and redness. It is a strong corticosteroid.</p>

Skin Diseases, Dermatitis, Allergic Contact, Psoriasis Vulgaris + 1 more

Treatment

20 Active Studies for Topicort

Treatment for

Skin Diseases

What is Topicort

Desoximetasone

The Generic name of this drug

Treatment Summary

Glucocorticoid creams are topical anti-inflammatory medications used to treat skin conditions such as dermatitis, skin allergies, and psoriasis.

Desoximetasone

is the brand name

Topicort Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Desoximetasone

1985

Effectiveness

How Topicort Affects Patients

Desoximetasone is a type of medication that reduces inflammation, itching, and constricts blood vessels when applied to the skin. It is a powerful drug and should not be used with tightly sealed bandages. It should only be used for two weeks at a time and stopped once the desired results are achieved.

How Topicort works in the body

Topical steroids reduce inflammation, but how they do this is not known for sure. It's thought that they work by changing the way cells make certain molecules that cause inflammation. Steroids bind to receptors in cells and then move inside the cell and bind to DNA, which causes certain genes to be activated or turned off. This then changes the way cells make molecules like prostaglandins and leukotrienes, which are linked to inflammation. The process is thought to start with the drug blocking the release of arachidonic acid from cell membranes, which is needed to make these molecules.

When to interrupt dosage

The suggested dosage of Topicort is contingent upon the specified condition, for instance Atopic Dermatitis, corticosteroid-responsive dermatoses and Psoriasis. The measure can be found in the table below, contingent upon the technique of delivery (e.g. Topical or Cream - Topical).

Condition

Dosage

Administration

Skin Diseases

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion - Topical, Emulsion

Psoriasis Vulgaris

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion - Topical, Emulsion

Psoriasis

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion - Topical, Emulsion

Dermatitis, Allergic Contact

0.0025 mg/mg, , 0.0005 mg/mg, 2.5 mg/mL, 0.05 %, 0.25 %

Topical, , Ointment, Cream, Ointment - Topical, Cream - Topical, Gel - Topical, Gel, Spray - Topical, Spray, Emulsion - Topical, Emulsion

Warnings

There are 20 known major drug interactions with Topicort.

Common Topicort Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abatacept.

Abetimus

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with Abetimus.

Acteoside

Major

The risk or severity of adverse effects can be increased when Desoximetasone is combined with Acteoside.

Topicort Toxicity & Overdose Risk

Applying desoximetasone to the skin may lead to an overdose which can cause thinning of the skin and a weakened ability of the adrenal gland to respond to stress.

Topicort Novel Uses: Which Conditions Have a Clinical Trial Featuring Topicort?

88 active trials are currently examining the potential of Topicort to address Psoriasis, Atopic Dermatitis and Plaque Psoriasis.

Condition

Clinical Trials

Trial Phases

Dermatitis, Allergic Contact

0 Actively Recruiting

Skin Diseases

0 Actively Recruiting

Psoriasis Vulgaris

22 Actively Recruiting

Early Phase 1, Phase 3, Phase 4, Phase 2, Not Applicable

Psoriasis

0 Actively Recruiting

Topicort Reviews: What are patients saying about Topicort?

Patient Review

4/26/2012

Topicort for Skin Rash that Becomes Thick & Discolored From Rubbing It

I've been using this medication for a while now, but my recent responsibilities as a caregiver have exacerbated my condition. Thankfully, Topicort was able to quickly clear up my skin in just three days. It's dry, so I just use a thin layer of Vaseline to keep it moistened.

Patient Review

10/18/2008

Topicort for Plaque Psoriasis

I've had psoriasis for most of my life, and Topicort is the only thing that has ever worked well for me. Within two days, my skin was 90% better...and with consistent use, it should stay that way.

Patient Review

3/9/2010

Topicort for Skin Condition

I had a great experience with this treatment. It cleared up my lichen planis quickly and I haven't had any problems since.

Patient Review

7/8/2010

Topicort for Reddish Nodules Arranged in a Circle On the Skin

This was the only medicated cream that quickly and effectively cleared up my rash. I've tried other creams before, but they only made the rash worse and it would spread more quickly. If you're dealing with a similar issue, I highly recommend this cream.

Patient Review

5/28/2011

Topicort for Skin Condition

I was really amazed at how quickly this treatment worked. My skin condition disappeared within just two days!

Patient Review

6/2/2020

Topicort for Plaque Psoriasis

This medication always gets rid of my psoriasis for a good length of time. I highly recommend it!

4.7

Patient Review

12/20/2009

Topicort for Atopic Dermatitis

The cream has effectively treated the redness and scaling on my leg, though I'm not sure what the exact diagnosis is. I've only been using it for a short time so I can't speak to long-term results yet.

4.7

Patient Review

3/27/2014

Topicort for Atopic Dermatitis

I developed a rash for no apparent reason and tried several over-the-counter creams to no avail. Finally, I went to the dermatologist who prescribed this medication. It cleared up the rash within just a couple of days - super easy and effective.

4.7

Patient Review

1/2/2013

Topicort for Atopic Dermatitis

This treatment quickly got rid of my itchiness and redness. I only had to use it once or twice a day for about a week, which was really convenient.

Patient Review

5/18/2008

Topicort for Scaly Oily Skin Problem Primarily On Face and Scalp

I had a problem with dry, bumpy acne on my chin. I used this treatment once a day for two weeks and it cleared the problem right up.

3.7

Patient Review

7/28/2008

Topicort for Rash

Itching and swelling were both much better within 24 hours. I had a bad case of heat rash, but this treatment really helped.

3.3

Patient Review

7/26/2009

Topicort for Rash

I am currently using this product to treat poison ivy, and I was wondering if it would be okay to wear a long sleeve shirt over the treatment.

2.7

Patient Review

3/5/2009

Topicort for Reddish Nodules Arranged in a Circle On the Skin

I went back to the dermatologist after a spot developed on my hand. They zapped it with liquid nitrogen, but now it's worse...

2.3

Patient Review

4/18/2014

Topicort for Skin Condition

The price is way too expensive for the amount you get.

Patient Q&A Section about topicort

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long does it take Topicort to work?

"This medication contains a topical anti-inflammatory drug from the cortisone family (corticosteroid). Typically, it is used to treat inflammation and itching. It requires several days for the medication to take effect."

Answered by AI

What are the side effects of desoximetasone?

"The following are symptoms of a reaction to a medication: burning, itching, irritation, redness, or dryness of the skin; tiny red bumps or rash around the mouth; unwanted hair growth; acne; small white or red bumps on the skin; bruising or shiny skin; red or purple blotches or lines under the skin; thin, fragile, or dry skin."

Answered by AI

Is Topicort ointment a steroid?

"Desoximetasone is a steroid medication that is applied to the skin to treat conditions like inflammation and plaque psoriasis."

Answered by AI

What is Topicort used to treat?

"This medication is used to treat conditions such as eczema, dermatitis, allergies, and rash by reducing swelling, itching, and redness. It is a strong corticosteroid."

Answered by AI