Arthrotec

Contusions, Pain, Photophobia + 54 more

Treatment

10 FDA approvals

20 Active Studies for Arthrotec

What is Arthrotec

Diclofenac

The Generic name of this drug

Treatment Summary

Misoprostol is a medication used to reduce the risk of ulcers caused by taking certain types of NSAID drugs. It can also be used to manage miscarriages, prevent post-partum bleeding, and terminate early pregnancies. Misoprostol works by stimulating prostaglandin receptors in the stomach and uterus, which reduces gastric acid production, and increases the strength and frequency of uterine contractions. The FDA approved misoprostol in 1988.

Voltaren

is the brand name

image of different drug pills on a surface

Arthrotec Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Voltaren

Diclofenac

1988

767

Approved as Treatment by the FDA

Diclofenac, also called Voltaren, is approved by the FDA for 10 uses including Osteoarthritis of the Knee and Pain .

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Pain

Helps manage Pain

Osteoarthritis

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Osteoarthritis (OA)

Used to treat Osteoarthritis (OA) in combination with Misoprostol

Stomach Ulcer

Used to treat develop NSAID-induced gastric ulcers in combination with Misoprostol

Postoperative Inflammatory Response

Chronic Pain

Helps manage Pain

Osteoarthritis of the Knee

Used to treat Osteoarthritis of the Knee in combination with Capsaicin

Rheumatoid Arthritis

Cataract Surgery

Effectiveness

How Arthrotec Affects Patients

Misoprostol is a medication that helps protect the stomach from ulcers caused by taking NSAIDs. It can also help manage miscarriages and can be used on its own or with another drug, mifepristone, to terminate a pregnancy in the early stages. Depending on the method of administration, it may take 8-100 minutes to take effect, and its effects last for 2-4 hours.

How Arthrotec works in the body

Misoprostol is a medication that reduces stomach acid, increases mucus and bicarbonate secretion, and thickens the protective layer of the stomach. It also makes contractions in the uterus stronger and more frequent, while loosening the neck of the uterus.

When to interrupt dosage

The advised measure of Arthrotec is contingent upon the diagnosed ailment, including Incomplete Abortion, prophylaxis of Gastric ulcer and Missed Abortion. The measure of dosage can be found in the table beneath, contingent upon the delivery technique (e.g. Tablet - Oral or Oral).

Condition

Dosage

Administration

Contusions

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Arthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Photophobia

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Muscle Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Chronic Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Pericarditis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Postoperative Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Rheumatism

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Arthritis, Gouty

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Pain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Dysmenorrhea

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Inflammation

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Juvenile arthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Actinic Keratosis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Muscle Strain

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Osteoarthritis

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Wounds, Nonpenetrating

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Collagen Diseases

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Cataract Surgery

100.0 mg, , 1.0 mg/mL, 50.0 mg, 75.0 mg, 16.05 mg/mL, 3.5 mg/mL, 25.0 mg, 0.01 mg/mg, 180.0 mg, 0.018 mg/mg, 1.0 mg/mg, 0.1 %, 1.5 %, 30.0 mg/mL, 0.03 mg/mg, 2.32 %, 1.16 %, 37.5 mg/mL, 0.02 mg/mg, 18.0 mg, 35.0 mg, 0.3 mg/mg, 10.0 mg, 1000.0 mg, 10.0 mg/mL, 12.5 mg, 0.015 mg/mg, 100.0 mg/mL, 3.0 mg/mg, 5.7 mg/mg, 13.0 mg, 0.013 mg, 0.001 mg/mg

, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Oral, Ophthalmic, Solution, Solution - Ophthalmic, Tablet, delayed release, Tablet, delayed release - Oral, Topical, Solution - Topical, Tablet, Powder, for solution, Powder, for solution - Oral, Solution / drops, Solution / drops - Ophthalmic, Tablet, film coated, Tablet, film coated - Oral, Liquid, Liquid - Topical, Gel, Gel - Topical, Patch, Patch - Topical, Liquid - Ophthalmic, Rectal, Suppository - Rectal, Suppository, Tablet - Oral, Kit, Aerosol, metered, Aerosol, metered - Topical, Intravenous, Injection, solution - Intravenous, Injection, solution, Cream, Powder - Oral, Transdermal, Solution / drops - Transdermal, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule - Oral, Cream - Topical, Tablet, extended release, Tablet, extended release - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Kit - Topical, Capsule, Kit - Oral; Topical, Sublingual, Oral; Topical, Tablet, coated - Oral, Drug delivery system - Topical, Drug delivery system, Tablet, coated

Warnings

Arthrotec has one contraindication, and it should not be taken when experiencing the conditions listed in the table below.

Arthrotec Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

Heart failure

Do Not Combine

Crohn's Disease

Do Not Combine

recent history of anal bleeding

Do Not Combine

Hemorrhagic Disorders

Do Not Combine

Gastritis

Do Not Combine

inflammatory lesions of the Rectum

Do Not Combine

active Gastrointestinal Bleeding

Do Not Combine

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

active Gastrointestinal Perforation

Do Not Combine

Duodenal Ulcer

Do Not Combine

Coronary Artery Bypass Grafting

Do Not Combine

Severe Hepatic Impairment

Do Not Combine

Ulcerative Colitis

Do Not Combine

Liver Diseases

Do Not Combine

Stroke

Do Not Combine

Third trimester of pregnancy

Do Not Combine

Hematochezia

Do Not Combine

Kidney Failure

Do Not Combine

Kidney Failure

Do Not Combine

Anus

Do Not Combine

Ulcer

Do Not Combine

damaged skin

Do Not Combine

Gastric ulcer

Do Not Combine

Peptic Ulcer

Do Not Combine

Hyperkalemia

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Diclofenac may interact with Pulse Frequency

There are 20 known major drug interactions with Arthrotec.

Common Arthrotec Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Diclofenac.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Diclofenac.

Cyclophosphamide

Major

The metabolism of Cyclophosphamide can be decreased when combined with Diclofenac.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Diclofenac.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Diclofenac.

Arthrotec Toxicity & Overdose Risk

The toxic dose of misoprostol in rats is 81mg/kg and 27mg/kg in mice. Overdosing on misoprostol can lead to drowsiness, shaking, seizures, difficulty breathing, stomach pain, diarrhea, fever, heart palpitations, low blood pressure, and slow heartbeat. Dialysis is not likely to help, but activated charcoal taken by mouth may reduce absorption. To treat an overdose, supportive care should be provided which may include removing undissolved tablets, fluids, pain relievers, and other medications depending on the symptoms.

image of a doctor in a lab doing drug, clinical research

Arthrotec Novel Uses: Which Conditions Have a Clinical Trial Featuring Arthrotec?

3 active trials are currently being conducted to explore the potential of Arthrotec in providing Medically induced abortion, prophylaxis of Gastric ulcer and NSAID use.

Condition

Clinical Trials

Trial Phases

Osteoarthritis of the Knee

85 Actively Recruiting

Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1

Inflammation

61 Actively Recruiting

Not Applicable, Phase 2, Early Phase 1, Phase 3, Phase 1

Chronic Pain

128 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Rheumatoid Arthritis

63 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Postoperative Pain

21 Actively Recruiting

Not Applicable, Phase 4, Phase 2, Phase 1, Early Phase 1, Phase 3

Dysmenorrhea

0 Actively Recruiting

Muscle Pain

2 Actively Recruiting

Phase 4, Phase 2

Conjunctivitis

0 Actively Recruiting

Musculoskeletal System

1 Actively Recruiting

Not Applicable

corneal refractive surgery

0 Actively Recruiting

Postoperative Inflammatory Response

0 Actively Recruiting

Photophobia

5 Actively Recruiting

Not Applicable

Pain

2 Actively Recruiting

Not Applicable

Stomach Ulcer

0 Actively Recruiting

Rheumatism

0 Actively Recruiting

Juvenile arthritis

7 Actively Recruiting

Phase 2, Not Applicable, Phase 3

radial keratotomy

0 Actively Recruiting

Joints

0 Actively Recruiting

Pericarditis

3 Actively Recruiting

Phase 2, Phase 3

Acute Coryza

0 Actively Recruiting

Arthrotec Reviews: What are patients saying about Arthrotec?

5

Patient Review

12/26/2014

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

I've been taking this medication for four days now and I'm already seeing a lot of improvement. I used to take ibuprofen for my arthritis pain, but this Arthrotec 50 is much better. I don't have any pain in my hands, back, etc., and I can finally sleep through the night.

5

Patient Review

11/9/2013

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

Arthrotec has given me such relief from my osteoarthritis pain. It's been a lifesaver, working almost immediately to provide pain relief. I highly recommend it to anyone struggling with similar issues.

5

Patient Review

1/5/2016

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

Aethrotec 50 was prescribed to me by my doctor to help with the pain while I waited for hip replacements. It's the only thing that's helped and it's been a miracle. I don't need surgery anymore and I can live again thanks to this medication. The downside is that it's hard on my stomach and bowels, but it's worth it!

5

Patient Review

9/16/2013

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

I was struggling with knee pain for over a year and wasn't getting any relief from other methods. This treatment has been really effective in managing my pain, to the point where I can now skip a day without having too much discomfort.

5

Patient Review

3/4/2014

Arthrotec for Rheumatoid Arthritis and High Risk of Developing Gastric Ulcers

I would not recommend this to people who are struggling with swelling, as it only made my own edema worse.

5

Patient Review

1/12/2016

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

I've been on this drug for nearly two decades and it's changed my life. The pain I was in before starting this treatment was so bad that I couldn't walk most days. But since taking it, I haven't had any negative side effects.

5

Patient Review

2/26/2022

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

I was in a lot of pain before starting this treatment, and I'm amazed at how quickly it's helped.

5

Patient Review

7/4/2013

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

4.7

Patient Review

3/30/2014

Arthrotec for Rheumatic Disease causing Pain & Stiffness in Backbone

This treatment has allowed me to do things I really enjoy again, like going out to eat or see a movie. Before, even just walking around my own house was agonizing due to the swelling and pain in my knee.

4.7

Patient Review

3/29/2015

Arthrotec for Rheumatoid Arthritis and High Risk of Developing Gastric Ulcers

This drug has been really effective for me and it's allowed me to do things that I haven't been able to do in years, like walk long distances. I don't have any side effects from it which is great. I've been using it for 6-8 months now and hopefully it will continue to be effective.

4.7

Patient Review

1/25/2022

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

I had to stop taking opioids because my GP wasn't willing to prescribe them. I've got general osteoarthritis and this treatment (Arthrotec 50mg) has worked great for me with few side effects. I only take it 5x per week because I don't want to constantly monitor my blood levels. Highly recommended!

4

Patient Review

6/22/2014

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

After months of severe pain, I took Arthrotec for 3-4 days and it worked very well. I stopped taking it after that and it also worked well on a toothache.

3.7

Patient Review

2/8/2014

Arthrotec for Osteoarthritis and High Risk of Developing Gastric Ulcers

I take this medication for migraines and it has been really effective. I still get the aura but no pain after.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about arthrotec

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can Arthrotec be used for body pain?

"Arthrotec contains diclofenac, a nonsteroidal anti-inflammatory drug, and misoprostol. The diclofenac in Arthrotec works by reducing substances in the body that cause pain and inflammation. Arthrotec is taken once or twice daily."

Answered by AI

Is Arthrotec the same as diclofenac?

"It helps to protect the stomach lining from the effects of diclofenac.

Arthrotec is a combination of diclofenac and misoprostol. Diclofenac is an NSAID, which blocks the production of chemicals that cause pain and inflammation. Misoprostol is a prostaglandin E1 analog, which helps protect the stomach lining from the effects of diclofenac."

Answered by AI

Is Arthrotec the same as ibuprofen?

"The drugs Arthrotec and ibuprofen both contain a nonsteroidal anti-inflammatory drug (NSAID). Arthrotec also contains a prostaglandin that protects the stomach from the irritating effects of NSAIDs. Ibuprofen is available under brand names such as Advil and Motrin, and also as a generic drug."

Answered by AI

What is Arthrotec used for?

"Arthrotec 75 is a non-steroidal, anti-inflammatory drug that is effective in treating the signs and symptoms of arthritic conditions. Diclofenac, an active ingredient in Arthrotec 75, is responsible for the drug's anti-inflammatory and analgesic properties."

Answered by AI

Clinical Trials for Arthrotec

Image of Massachusetts General Hospital in Boston, United States.

Vagus Nerve Stimulation for Fibromyalgia

18 - 80
All Sexes
Boston, MA

Fibromyalgia is a syndrome with clinical symptoms that affect multiple systems of the body. Although basic science research and clinical research trials have been carried out, the cause and the mechanism of fibromyalgia are still unknown. The goal of current medical treatment is to relieve symptoms and improve quality of life. Recent clinical and experimental studies have shown that stimulation of the vagus nerve has a potential to help pain syndromes. In this study, we aim to evaluate the effects of using transcutaneous vagus nerve stimulation (tVNS) on treating pain and other symptoms in fibromyalgia patients. We will do this by using the VagaCalm device.

Waitlist Available
Has No Placebo

Massachusetts General Hospital

Lucy Chen, M.D.

Image of Ohio State University in Columbus, United States.

Alcohol for Opioid Use Disorder

21 - 65
All Sexes
Columbus, OH

The goal of this clinical trial is to examine whether individuals with co-occurring opioid use disorder and alcohol use (OUD+ALC) experience heightened pain sensitivity, pain-related negative affect, and greater alcohol reinforcement compared with alcohol-only (ALC) or opioid-only (OUD-ALC) users. The main questions it aims to answer are: * Aim 1. Do individuals with OUD+ALC experience increased pain and pain-related negative affect during periods of sobriety relative to mono-users of alcohol (ALC only) and opioids (OUD-ALC)? * Aim 2. Do individuals with OUD+ALC experience greater alcohol-induced analgesia and alcohol reinforcement compared with mono-users of alcohol (ALC only) and opioids (OUD-ALC)? Participants will: * Complete a screening session * Complete one lab session including a comprehensive assessment battery involving multimodal assessments of pain during sobriety * Complete two experimental lab sessions that will include intravenous (IV) administration of either 80mg% alcohol or placebo (saline), order counterbalanced, to measure alcohol's acute effects on pain and pain-related negative affect

Phase < 1
Waitlist Available

Ohio State University

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Image of Northwell health physician partners in Bay Shore, United States.

Lidocaine Injection vs Saline for Pain Management

18+
Female
Bay Shore, NY

We are doing this study to find the best way to manage pain during a procedure called urethral bulking. This procedure treats urine leakage that happens with coughing, laughing, sneezing, or physical activity. It works by injecting a gel-like substance around the urethra (the tube that urine comes out of) to help it stay closed when it should. We use a numbing gel (called lidocaine jelly) inside the urethra to help with pain during the procedure. In this study, we will also be administering lidocaine (numbing medication) injected around the urethra or a saline placebo (medical grade saltwater) injection, which has no numbing effect. A placebo is something that looks like a real treatment but doesn't have any medical effect. Both the lidocaine and the saline would be injected around the urethra using a small needle, and we'll compare how well they work at reducing pain.

Phase 4
Recruiting

Northwell health physician partners (+2 Sites)

Image of Endeavor Health/NorthShore in Skokie, United States.

Tranexamic Acid for Anterior Cruciate Ligament Injury

14 - 25
All Sexes
Skokie, IL

The goal of this clinical trial is to learn whether taking oral tranexamic acid (TXA) for one week after anterior cruciate ligament (ACL) reconstruction improves recovery in adolescents and young adults aged 14 to 25 years. All participants receive standard intravenous TXA during surgery. The main questions it aims to answer are: * Does oral TXA lower knee pain at 2 weeks after surgery? * Does oral TXA reduce the amount of opioid pain medicine used in the first 2 weeks? * Does oral TXA improve knee range of motion at 2 weeks? Researchers will compare oral TXA to a placebo (a look-alike capsule with no active drug) to see if oral TXA improves pain, opioid use, motion, strength, knee function, and return to sport. Participants will: * Take 3 capsules (oral TXA or placebo) once a day for the first 8 days after surgery (day of surgery through day 7) * Keep a home diary for 2 weeks recording pain scores, opioid pills taken and any side effects * Return for study visits at 2 weeks, 6 weeks, 12 weeks, 6 months, 9 months and 1 year for pain, motion, strength and function testing * Complete a survey at 2 years

Phase 3
Waitlist Available

Endeavor Health/NorthShore (+5 Sites)

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We made a collection of clinical trials featuring Arthrotec, we think they might fit your search criteria.
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Image of Northwestern Medicine Rheumatology in Chicago, United States.

Patient-Reported Outcomes Dashboard for Inflammatory Arthritis

18+
All Sexes
Chicago, IL

The goal of this clinical trial is to learn whether showing patient-reported symptoms and personal treatment goals to rheumatology clinicians on a dashboard in the electronic health record improves shared decision-making for adults with rheumatoid arthritis or psoriatic arthritis. The main questions it aims to answer are: * Do patients whose clinicians use the dashboard report more shared decision-making during their rheumatology visits than patients who receive usual care? * Do patients in the dashboard group report greater progress toward their personal goals and more confidence in managing their symptoms after 6 months? Researchers will compare the dashboard group to a usual care group to see if the dashboard improves shared decision-making, goal attainment, and self-efficacy. Participants will: * Complete a routine symptom questionnaire before their rheumatology visits, as all clinic patients do * Choose personal treatment goals and rate their progress toward those goals 6 months later * Complete short surveys before and after two rheumatology visits about 6 months apart Participants in the dashboard group will also complete questionnaires in the patient portal about pain, fatigue, physical function, sleep, and morning stiffness before each visit. Their answers and goals will be shown to their clinician on a dashboard to guide the conversation during the visit.

Waitlist Available
Has No Placebo

Northwestern Medicine Rheumatology

Image of Hospital for Special Surgery in New York, United States.

Suzetrigine for Pain Management in Total Knee Replacement

18 - 80
All Sexes
New York, NY

Total knee replacements are among the most common and painful orthopedic procedures performed worldwide, often requiring intensive analgesia to support early ambulation and recovery. Despite widespread use of multimodal regimens, many patients still rely on opioids, which can cause sedation, nausea, constipation, and long-term dependency. Evaluating suzetrigine in this high-need population may improve recovery trajectories, reduce opioid consumption, and support enhanced recovery protocols. Given the growing surgical volume and the emphasis on opioid-sparing strategies, rigorous investigation of suzetrigine's efficacy in total knee replacement is of high clinical value. In this confirmatory (phase III) trial, patients undergoing primary total knee replacement will be randomized to receive either suzetrigine or placebo for 2 weeks (14 days), with the loading dose administered prior to surgery. The primary outcome is cumulative 48-hour opioid consumption in oral morphine equivalents starting from entry into the post-anesthesia care unit (PACU).

Phase 3
Recruiting

Hospital for Special Surgery

Meghan Kirskey, MD

Image of Nicholas Institute of Sports Medicine & Athletic Trauma (NISMAT) in New York, United States.

Fruit Juice for Inflammation

18 - 65
All Sexes
New York, NY

Dietary patterns and physical inactivity common in Western societies have been associated with chronic low-grade inflammation and an increased risk of non-communicable health conditions. Fruits and vegetables contain polyphenols and other bioactive compounds that may have antioxidant and anti-inflammatory properties and may influence inflammatory biomarkers. This study will evaluate the effects of increased consumption of a fruit juice on inflammatory biomarkers and exercise capacity in adults with mildly elevated inflammation. Approximately 40 participants will be randomly assigned to consume one of two fruit juice interventions daily for approximately 2 weeks. Changes in C-reactive protein (CRP) and exercise capacity, assessed using a 6-minute walk test, will be evaluated before and after the intervention and compared between the two groups.

Recruiting
Has No Placebo

Nicholas Institute of Sports Medicine & Athletic Trauma (NISMAT)

Christopher Tanayan, MD

Image of Texas A&M University-Corpus Christi in Corpus Christi, United States.

Auricular Point Acupressure for Pain Management

18+
All Sexes
Corpus Christi, TX

The goal of this pilot clinical trial is to learn whether auricular point acupressure (APA) can help reduce chronic musculoskeletal pain in adults age 50 and older who are living with HIV. The study will also examine whether APA is feasible, acceptable, and safe for this population. The main questions it aims to answer are: Does APA reduce chronic musculoskeletal pain and improve sleep and quality of life? Is APA feasible, acceptable, and safe for older people living with HIV? Researchers will compare true APA, in which small seeds are taped to specific ear points related to pain, with sham APA, in which seeds are taped to ear points not related to pain. The intervention will last 4 weeks. Participants will: Receive true APA or sham APA for 4 weeks Visit the study site weekly for placement of the ear seeds Press the ear seeds for 3 minutes, 3 times each day Complete daily surveys about pain and pain medication use Use a sleep monitor to track sleep Complete study assessments at the beginning and end of the intervention Complete an exit interview about their experience with APA

Waitlist Available
Senior-friendly

Texas A&M University-Corpus Christi

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