Feedback Program for Reducing Antibiotic Overprescription

ER
DS
Overseen ByDana Stanley, MET
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of British Columbia
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if an educational program can reduce unnecessary antibiotic prescriptions by family doctors and nurse practitioners in British Columbia, Canada. The program, called the "Prescribing Portrait Audit and Feedback," provides a personalized prescribing "portrait" and a summary of evidence on appropriate antibiotic use. Researchers will compare two groups: one receives the program early, and the other receives it nine months later. The trial seeks healthcare providers who prescribed over 100 medications in 2024 and are registered with the BC Medical Services Plan. As an unphased trial, this study offers a unique opportunity to improve healthcare practices and reduce antibiotic misuse.

Do I have to stop taking my current medications for this trial?

The trial does not specify whether participants need to stop taking their current medications. It focuses on reducing unnecessary antibiotic prescriptions by healthcare providers, not on patient medication changes.

What prior data suggests that this educational intervention is safe for reducing antibiotic overprescription?

Research has shown that audit and feedback methods, such as the prescribing portrait, are generally safe in healthcare settings. These methods provide healthcare providers with personalized information about their prescribing habits to aid improvement. Studies have not identified any direct harm to patients or providers from these methods. Specifically, a large review involving 45.5 million years of follow-up found no safety issues related to these methods.

One study demonstrated that feedback to healthcare providers led to an 11% reduction in antibiotic prescriptions, indicating effective behavior change without harm. In summary, current evidence supports that the prescribing portrait and similar feedback methods are safe and well-tolerated by both healthcare providers and patients.12345

Why are researchers excited about this trial?

Researchers are excited about the Feedback Program for Reducing Antibiotic Overprescription because it focuses on changing clinician behavior through an innovative audit-and-feedback method. Unlike traditional approaches that often involve guidelines or education sessions, this program provides personalized feedback by using prescribing portraits and evidence summaries. This method aims to directly address overprescription by giving clinicians a clear view of their prescribing habits compared to best practices, potentially leading to more responsible antibiotic use.

What evidence suggests that this educational intervention is effective for reducing unnecessary antibiotic prescriptions?

Research has shown that giving feedback to healthcare professionals can help reduce the overuse of antibiotics. For instance, studies have found that this approach can lead to an 11% decrease in the amount of antibiotics prescribed. In this trial, the Early Group of clinicians will receive the prescribing portrait audit-and-feedback intervention at the study's initiation, while the Delayed Control group will receive it approximately 9 months later. This method provides doctors with information about their prescribing habits, aiding them in making better choices. The feedback compares their prescribing patterns to recommended guidelines. This type of intervention has successfully improved antibiotic prescribing and reduced unnecessary use.12567

Who Is on the Research Team?

CD

Colin Dormuth, ScD

Principal Investigator

University of British Columbia

Are You a Good Fit for This Trial?

This trial is for family doctors and nurse practitioners in British Columbia who are registered with the BC Medical Services Plan, have an active billing number, work in various practice settings, and have prescribed over 100 medications in 2024. Those who previously opted out of the Portrait program cannot join.

Inclusion Criteria

Registered in 2024 with the BC Medical Services Plan (MSP) with a valid MSP billing number
Status of Salaried, Private Practice, Temporary Licence, or Post Graduate
Prescribed more than 100 dispensed medications in 2024

Exclusion Criteria

I have chosen not to participate in the Therapeutics Initiative Portrait program before.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Early Group receives the prescribing portrait audit-and-feedback intervention at study initiation

9 months
Intervention materials mailed

Delayed Intervention

Delayed Group receives the prescribing portrait audit-and-feedback intervention approximately 9 months after the Early Group

9 months
Intervention materials mailed

Follow-up

Participants are monitored for changes in antibiotic prescribing rates and unnecessary prescriptions

39 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Prescribing portrait audit and feedback

Trial Overview

The study tests whether sending personalized feedback reports and educational materials to clinicians can reduce unnecessary antibiotic prescriptions. Participants are randomly assigned to get these materials either early or after nine months for comparison.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Early Group - Prescribing portrait audit and feedbackExperimental Treatment1 Intervention
Group II: Delayed control - Prescribing portrait audit-and-feedbackExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of British Columbia

Lead Sponsor

Trials
1,506
Recruited
2,528,000+

Ministry of Health, British Columbia

Collaborator

Trials
11
Recruited
15,600+

British Columbia Centre for Disease Control

Collaborator

Trials
11
Recruited
2,600+

Citations

Effectiveness of audit and feedback in addressing over ... - PMC

The study provides strong evidence that using theoretical insights in the development of the intervention improved prescribing behavior that lasted at least ...

Audit and Feedback Interventions for Antibiotic Prescribing in ...

This systematic review evaluates the effect of audit and feedback (A&F) interventions targeting antibiotic prescribing in primary care and examines factors that ...

Audit and Feedback - Therapeutics Letter - NCBI Bookshelf

The review found that the effectiveness of an antibiotic prescribing intervention depends to a large degree on the prescribing behaviour and the barriers to ...

Review finds audit and feedback improves antibiotic ...

They found that A&F was associated with an 11% relative reduction in antibiotic prescribing volume (rate ratio [RR], 0.89; 95% confidence ...

Audit and Feedback Interventions for Antibiotic Prescribing ...

Background This systematic review evaluates the effect of audit and feedback (A&F) interventions targeting antibiotic prescribing in primary ...

[127] Audit and Feedback: Personal Prescribing Portrait

The review found that the effectiveness of an antibiotic prescribing intervention depends to a large degree on the prescribing behaviour and the ...

Effect of Antibiotic Prescription Audit and Feedback on ... - PMC

The main objective of the present randomized clinical trial was to investigate the effect of patient-level claims data audit and feedback with ...