Holmium Laser Treatments for Enlarged Prostate
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial compares two laser technologies to determine which reduces blood loss more effectively during surgery for an enlarged prostate. The Magneto 150 holmium laser is tested against the current MOSES 2.0 holmium laser technology. Men scheduled for HoLEP surgery, who experience bothersome urinary symptoms, might be suitable candidates. Participants must have internet access to complete surveys after their surgery. As an unphased trial, this study allows participants to contribute to advancements in surgical technology and improve outcomes for future patients.
What prior data suggests that these holmium laser treatments are safe for enlarged prostate procedures?
Research has shown that holmium laser treatments, such as the Magneto 150 and Moses 2.0 lasers, are generally safe for individuals with an enlarged prostate. Studies have found these treatments to be well-tolerated, often resulting in fewer complications than traditional surgery. One ten-year study demonstrated that holmium laser therapy is a safe and effective treatment for Benign Prostatic Hyperplasia (BPH), the medical term for an enlarged prostate. Most patients recover quickly and experience fewer side effects.
While specific safety data for the Moses 2.0 laser is not yet available, it is another type of holmium laser used in similar procedures. Given the established safety of holmium lasers, Moses 2.0 is likely to be safe as well. Overall, both laser treatments have strong safety records for treating enlarged prostate conditions.12345Why are researchers excited about this trial's treatments?
Researchers are excited about the Holmium Laser Treatments for Enlarged Prostate, featuring the Magneto 150 and Moses 2.0 lasers, because they offer a new way to perform the HoLEP procedure with more precision and efficiency. Unlike traditional treatments that may rely on older laser technologies or surgical methods, these lasers are designed to minimize bleeding and reduce procedure time, potentially leading to quicker recovery for patients. Each laser has its unique advantages—Moses 2.0 is known for enhanced energy delivery, while Magneto 150 is an experimental option that could provide even greater control and effectiveness.
What evidence suggests that these laser treatments could be effective for an enlarged prostate?
Research has shown that holmium laser treatments, such as those used in HoLEP (Holmium Laser Enucleation of the Prostate), effectively treat an enlarged prostate. Studies have found that HoLEP works well for all sizes of prostate enlargement and provides results similar to traditional prostate surgery. Patients often experience shorter hospital stays and less pain. This trial compares the Magneto 150 holmium laser to the Moses 2.0 laser. Early findings suggest both lasers perform well, but the Magneto 150 may help reduce bleeding during surgery.12346
Who Is on the Research Team?
Perry Xu, MD
Principal Investigator
Northwestern University
Are You a Good Fit for This Trial?
This trial is for people with bothersome urinary symptoms from an enlarged prostate who are scheduled to have HoLEP surgery. Participants need internet access and a device to complete online questionnaires.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo the HoLEP procedure using either the Moses 2.0 or Magneto 150 holmium laser
Follow-up
Participants are monitored for safety and effectiveness after the surgical procedure
What Are the Treatments Tested in This Trial?
Interventions
- Magneto 150 holmium laser
- Moses 2.0 holmium laser
Trial Overview
The study compares two types of holmium lasers, Magneto 150 and Moses 2.0, used during HoLEP surgery for enlarged prostate, to see which one reduces bleeding time better. Patients are randomly assigned to either laser group.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
HoLEP procedure performed using Magneto 150 holmium laser
HoLEP procedure performed using the Moses 2.0 holmium laser
Find a Clinic Near You
Who Is Running the Clinical Trial?
Northwestern University
Lead Sponsor
Cook Group Incorporated
Industry Sponsor
Carl Cook
Cook Group Incorporated
Chief Executive Officer since 2011
Bachelor's degree in Engineering from Purdue University, MBA from the University of Iowa
Dr. John A. Kaufman
Cook Group Incorporated
Chief Medical Officer since 2023
MD
Citations
The Efficacy and Safety of Holmium Laser Enucleation ... - PMC
The holmium laser group had favorable perioperative outcomes in this study. The holmium laser group identified shorter catheterization duration. Holmium lasers ...
Moses 2.0 vs Magneto for HoLEP
The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in ...
Enlarged prostate: decade-long study demonstrates ...
The researchers point out that HoLEP is more effective at adequately treating all sizes of prostatic enlargement, whereas other laser techniques ...
4.
hopkinsmedicine.org
hopkinsmedicine.org/health/conditions-and-diseases/benign-prostatic-hyperplasia-bph/prostate-holmium-laser-enucleation-holepHoLEP Procedure: Holmium Laser Enucleation of the ...
In terms of effectiveness, practitioners report that holmium laser enucleation of the prostate has results comparable to those of simple prostatectomy but does ...
Cyber Ho Magneto HoLEP Device ...
effective results can be achieved for small, medium, and large prostates. Patients often experience less pain, have a shorter hospital stay, ...
6.
my.clevelandclinic.org
my.clevelandclinic.org/health/treatments/17917-holmium-laser-enucleation-of-the-prostate-holepHolmium Laser Enucleation of the Prostate (HoLEP)
The holmium laser is a surgical laser that surgeons use to remove the bulky prostate tissue that's blocking the flow of pee. The most common ...
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