Decision Support Tool for Pancreatic Cancer

TB
Overseen ByTrevor Barlowe, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: UNC Lineberger Comprehensive Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a tool designed to help individuals at high risk of pancreatic cancer make informed decisions about screening. The electronic decision support tool aims to enhance communication between patients and healthcare providers. Individuals advised by their doctor to consider pancreatic cancer screening, who are not currently in a screening program and can speak English, may be suitable for this study. Participants will either use the new tool or follow the usual care process to evaluate the tool's effectiveness in real-life medical settings. As an unphased trial, this study allows participants to contribute to innovative research that could improve decision-making for pancreatic cancer screening.

What prior data suggests that this electronic decision support tool is safe for pancreatic cancer screening?

Research has shown that electronic decision support tools, like the one under testing, are generally safe. These tools are software programs that assist individuals in making informed health decisions. As a software tool, it does not carry the same safety concerns as drugs or medical devices. No reports have indicated problems directly caused by these tools. Similar tools are already in use in other healthcare areas to aid decision-making. For those considering joining this trial, the tool itself poses no known risks to health.12345

Why are researchers excited about this trial?

Researchers are excited about the electronic decision support tool for pancreatic cancer screening because it brings a personalized approach to patient care. Unlike the traditional method, where decisions are often made solely by healthcare providers, this tool encourages shared decision-making by providing patients with tailored information and support. This empowers patients to be more involved in their health choices, potentially leading to more informed and satisfactory decisions about their screening options. By integrating technology into clinical care, this tool aims to enhance patient engagement and improve the overall screening process.

What evidence suggests that this electronic decision support tool is effective for pancreatic cancer screening?

Studies have shown that decision support tools can help detect pancreatic cancer early. Research indicates that these tools, often using artificial intelligence (AI), can identify high-risk individuals up to three years before diagnosis. In some programs using these tools, patients achieved a five-year survival rate of 73.3%, with an average survival time of 9.8 years. In this trial, participants in one arm will use an electronic decision support tool to assist doctors and patients in making informed decisions about screening. This is crucial given the uncertainty surrounding the benefits of current screening methods. By utilizing health records and predictive algorithms, these tools aim to catch cancer early, potentially improving patient outcomes.678910

Who Is on the Research Team?

TB

Trevor Barlowe, MD

Principal Investigator

UNC Lineberger Comprehensive Cancer Center

Are You a Good Fit for This Trial?

This trial is for people at high risk for pancreatic cancer, such as those with certain genetic conditions or family history. The study aims to help these individuals and their doctors make informed decisions about screening.

Inclusion Criteria

I meet the guidelines for pancreatic cancer screening as an adult.
English-speaking
Not currently enrolled in a pancreatic cancer screening program
See 2 more

Exclusion Criteria

I do not qualify for pancreatic cancer screening under NCCN guidelines.
Non-English speaking
I am unable or unwilling to give my consent for the study.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants use an electronic decision support tool to aid in shared decision-making regarding pancreatic cancer screening

Up to 3 months
Multiple clinic visits

Follow-up

Participants are monitored for acceptability, feasibility, and implementation of the decision support tool

Up to 3 months

What Are the Treatments Tested in This Trial?

Interventions

  • Electronic Decision Support Tool

Trial Overview

The study is testing an electronic decision support tool designed to guide patients and healthcare providers through the process of deciding whether to undergo pancreatic cancer screening. It focuses on how useful and practical this tool is in real-world settings.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Electronic Decision Support ToolExperimental Treatment1 Intervention
Group II: Standard of CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

UNC Lineberger Comprehensive Cancer Center

Lead Sponsor

Trials
377
Recruited
95,900+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

Trials
394
Recruited
404,000+

Citations

Pancreatic Cancer Surveillance Programs Lead to Earlier ...

For the patients with surveillance-detected pancreatic cancer, five-year survival is 73.3% and median overall survival is 9.8 years, compared ...

2.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/34629446/

Early Detection of Pancreatic Cancer: Applying Artificial ...

This review article reflects the findings from the workshop and assesses the feasibility of AI-based data extraction and modeling applied to ...

Decision support tools for pancreatic cancer detection

Decision support tools for pancreatic cancer detection: external validation in Australian primary care — a retrospective cohort study. S Schrader, M Rafiq, J ...

AI Tool Uses Medical Records to Identify High-Risk ...

A deep-learning algorithm has successfully identified people at the highest risk for pancreatic cancer up to three years before diagnosis ...

The Debate Over Early Screening for Pancreatic Cancer ...

The diagnostic yield for highrisk pancreatic lesions regardless of the form of screening was found to be 0.74 (95% CI, 0.33-1.14).

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Google Help

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Official Apple Support

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SUPPORT Definition & Meaning

The meaning of SUPPORT is to promote the interests or cause of especially by action or aid. How to use support in a sentence.

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Microsoft Support

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SUPPORT | English meaning - Cambridge Dictionary

If you support an activity or a habit, you provide the money needed to pay for it: The drug company is supporting cancer research. order to support their habit.