Coronary Artery Calcium Testing for Cardiovascular Disease
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this study is to improve how primary care providers identify and manage patients at risk for heart disease. One tool that can help with this is a coronary artery calcium (CAC) test, which looks for calcium buildup in the heart's arteries and can help estimate a person's risk of future heart problems.
The main questions this study aims to answer are:
Will a new electronic health record (EHR) alert that provides guidance on when to consider a CAC test be feasible and acceptable to primary care providers? Does the alert change how often providers order CAC tests, start or change the dose of cholesterol-lowering medications, and refer patients to cardiology?
In this study, a new EHR alert will be implemented as part of routine clinical practice for primary care providers at Weill Cornell Internal Medicine Associates (WCIMA). The alert will provide guidance on considering a CAC test, cholesterol-lowering medication, or referral to cardiology for eligible patients. Researchers will compare clinical care before and after the alert is implemented. They will look at how often CAC tests are ordered and completed, how often cholesterol-lowering medications are started or their doses are changed, and how often patients are referred to cardiology. After the implementation period, primary care providers will also be asked to complete a brief survey and participate in an interview about the alert.
Who Is on the Research Team?
Madeline R Sterling, MD, MPH
Principal Investigator
Weill Medical College of Cornell University
Are You a Good Fit for This Trial?
This trial is for adult patients at risk for heart disease, such as those with high blood pressure or high cholesterol, who receive care at Weill Cornell Internal Medicine Associates. There are no detailed inclusion or exclusion criteria listed.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Implementation
Implementation of the electronic health record (EHR) alert for primary care providers to guide CAC testing, lipid-lowering therapy, and cardiology referrals
Post-implementation Evaluation
Evaluation of the impact of the EHR alert on clinical outcomes and provider feedback through surveys and interviews
Follow-up
Participants are monitored for changes in clinical practices and outcomes after the implementation period
What Are the Treatments Tested in This Trial?
Trial Overview
The study tests whether a new electronic health record alert helps primary care doctors decide when to order a coronary artery calcium (CAC) test, start or adjust cholesterol medicine, or refer patients to a heart specialist. Care before and after the alert will be compared.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
For 8 months, an Our Practice Advisory (OPA) will be visible to primary care providers within Epic. The OPA will be activated for eligible adults without established CVD who have borderline or intermediate PREVENT-estimated 10-year ASCVD risk and for whom lipid-lowering treatment decisions remain uncertain. The proposed actions will be to order a CAC test, consider referral to cardiology, and initiate or intensify lipid-lowering therapy, including dose titration when appropriate.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Weill Medical College of Cornell University
Lead Sponsor
Merck Sharp & Dohme LLC
Industry Sponsor
Chirfi Guindo
Merck Sharp & Dohme LLC
Chief Marketing Officer since 2022
Degree in Engineering from Ecole Centrale de Paris, MBA from New York University Stern School of Business
Robert M. Davis
Merck Sharp & Dohme LLC
Chief Executive Officer since 2021
JD from Northwestern University Pritzker School of Law, MBA from Northwestern University Kellogg Graduate School of Management, Bachelor's in Finance from Miami University
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