454 Participants NeededMy employer runs this trial

Counseling Support for Cancer Survivors

Recruiting at 6 trial locations
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if brief behavioral activation (BBA) can improve depression, anxiety, and overall well-being in older adult cancer survivors. BBA encourages participants to set goals and engage in enjoyable activities to enhance mood and lifestyle. The trial includes 10 sessions conducted over the phone or via video chat. It is suitable for English- or Spanish-speaking cancer survivors aged 65 and older who are currently cancer-free or at least six months post-treatment. Participants should feel comfortable communicating remotely and seek to improve their mental health and lifestyle. As an unphased trial, this study offers a unique opportunity for participants to contribute to valuable research that could enhance mental health support for older cancer survivors.

What prior data suggests that this psychotherapy method is safe for older adult cancer survivors?

Research has shown that Brief Behavioral Activation (BBA) is generally safe for people with depression, including those with cancer. Studies have found that many individuals complete BBA treatment and experience reduced depressive symptoms. No strong evidence of serious side effects from BBA exists, making it a well-tolerated option for many. This approach involves setting personal goals and engaging in enjoyable activities to boost mood and behavior, effectively improving emotional well-being.12345

Why are researchers excited about this trial?

Researchers are excited about the Counseling Support for Cancer Survivors trial because it's exploring innovative ways to help cancer survivors manage depression and improve their quality of life. Unlike traditional therapy methods, the Brief Behavioral Activation (BBA) treatment focuses on actively engaging survivors in enjoyable activities that align with their values, aiming to boost mood and satisfaction through structured phone or video sessions. This approach is unique in its emphasis on daily activity scheduling and self-monitoring, which could offer a more practical and empowering way for survivors to cope with emotional challenges compared to standard supportive psychotherapy. By providing specific psychoeducation and inviting participants to share their cancer stories, the trial aims to personalize support in a meaningful way.

What evidence suggests that this trial's treatments could be effective for improving depression and anxiety in older adult cancer survivors?

Research has shown that Brief Behavioral Activation (BBA), which participants in this trial may receive, can help reduce depression and anxiety in cancer patients. Some studies found that BBA significantly improved mood and lessened the fear of cancer recurrence. It works as well as antidepressant medication and better than some other treatments. Many patients complete the treatment and experience fewer depressive symptoms. Overall, BBA may improve mental health and promote healthy habits in cancer survivors.36789

Who Is on the Research Team?

RS

Rebbeca Saracino, PhD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Are You a Good Fit for This Trial?

This trial is for cancer survivors aged 65 or older who speak English or Spanish. Participants should be able to take part in counseling sessions by phone or video call.

Inclusion Criteria

I am 65 years old or older.
Elevated score on the PHQ-9: ≥8 (N/A for Training Case participants)
Received a Blessed Orientation-Memory-Concentration Scale (BOMC) score of ≤ 11 (N/A for Training Case participants)
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Exclusion Criteria

As per PI determination, requires a higher level of care for current passive or active suicidal ideation than current protocol can provide; active suicidal ideation leads to exclusion and referral to higher care
I am currently in regular therapy that I cannot or do not want to pause.
I have trouble making medical decisions on my own.
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive brief behavioral activation (BBA) or supportive psychotherapy (SP) through 10 sessions of 30-50 minutes each via telephone or videoconference

10 weeks
10 sessions (remote)

Follow-up

Participants are monitored for changes in depression, anxiety, and overall well-being

1 year

What Are the Treatments Tested in This Trial?

Interventions

  • Brief Behavioral Activation (BBA)

Trial Overview

The study tests if a type of talk therapy called brief behavioral activation (BBA), delivered remotely, can help reduce depression and anxiety and improve well-being in older adult cancer survivors.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Behavioral Activation for Older Adult Cancer Survivor ( BBA-OAC)Experimental Treatment1 Intervention
Group II: Supportive Psychotherapy (SP)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials
1,998
Recruited
602,000+

National Institutes of Health (NIH)

Collaborator

Trials
2,896
Recruited
8,053,000+

Citations

Feasibility and Preliminary Effectiveness of Behavioral ... - PMC

Though the effectiveness of behavioral activation (BA) for patients with cancer and depression were reported, there is no evidence in Japan.

Protocol for a randomized controlled trial of brief behavioral ...

Over time, behaviors that may have been adaptive during cancer treatment, such as limiting activity levels, may increase depressive symptoms over the long term.

Behavioral activation for depression in patients with advanced ...

The program consists of seven sessions. The preliminary study showed high rates of treatment completion and remission of depressive symptoms, ...

Behavioral Activation Therapy for Depressed Cancer Patients

In an ongoing program of research, our research group demonstrated that behavioral activation may effectively treat depression in cancer patients. (Hopko, Bell, ...

Efficacy of behavioral activation in reducing fear of cancer ...

The results demon- strate that BA significantly reduced FCR levels in NSCLC patients, with this effect partially mediated by improvements in ...

Behavioral activation for depression in patients with advanced ...

The preliminary study showed high rates of treatment completion and remission of depressive symptoms, regardless of the stage of cancer, The ...

Effects of Behavioral Activation on Negative Emotions ...

This study aims to demonstrate the significant efficacy of behavioral activation in improving negative emotions, somatic symptoms, quality of life, and clinical ...

Feasibility and preliminary effectiveness of behavioral ...

BA may be particularly useful for treating depression in patients with cancer, but there is insufficient evidence in this population.

ACTIVA. Behavioral Activation and Acceptance and ...

Both treatment groups showed statistically significant changes, indicating an improvement in all the result variables in the post-treatment and ...