Alcohol Reduction + Probiotics for Alcohol Consumption

This trial tests whether a combination of motivational interviewing (a type of counseling) and probiotics can help older adults reduce alcohol consumption and improve brain health. Participants will receive either a probiotic supplement (Visbiome) or a placebo (a non-active pill resembling the supplement) along with motivational interviewing to assess its impact on brain function. The study seeks individuals aged 65 to 84 who drink heavily—defined as more than 14 drinks a week for men and more than 7 for women—and are interested in reducing their alcohol intake. As an unphased trial, it offers a unique opportunity to contribute to understanding innovative approaches for enhancing brain health and reducing alcohol consumption.

The trial does not specify if you need to stop taking your current medications, but you cannot participate if you are currently using probiotics, antibiotics, daily steroids, or immunosuppressants.

Research has shown that motivational interviewing is generally safe and well-tolerated. It has been proven to help reduce alcohol consumption. For example, one study found that participants reduced their drinking from 90 to 60 drinks per month after six months. Another study observed a decrease in daily drinking by about half a drink per day. These results suggest that motivational interviewing can help people drink less without causing harmful side effects.

Probiotics are usually safe for most people. These beneficial bacteria support gut health and are often found in foods like yogurt. While specific details about the probiotic used in this trial aren't provided, probiotics are generally well-tolerated and commonly used.

Researchers are excited about this trial because it explores a unique combination of motivational interviewing and probiotics to support alcohol reduction. While traditional treatments for alcohol consumption, such as counseling and medication, often focus solely on behavioral or pharmacological strategies, this approach integrates a probiotic supplement containing 900 billion CFUs to potentially enhance the effects of motivational interviewing. The probiotic is thought to influence gut health, which may play a role in reducing cravings and supporting healthier habits. By combining psychological support with a novel biological approach, this trial is paving the way for a potentially more effective and holistic treatment method for those looking to reduce their alcohol intake.

Research has shown that motivational interviewing, which participants in this trial will receive, can help reduce alcohol consumption. Studies have found this method more effective than standard health advice for reducing risky drinking. In this trial, one group will receive motivational interviewing combined with a probiotic supplement, while another group will receive motivational interviewing with a placebo. Evidence suggests that probiotics might aid in treating alcohol addiction by improving gut health. Combining these methods could offer dual benefits: changing drinking habits and enhancing overall health. Although more research is needed, early findings are promising for those looking to reduce alcohol intake.¹³⁶⁷⁸