240 Participants NeededMy employer runs this trial

Music Therapy for Anxiety in Cancer

Recruiting at 6 trial locations
JM
KL
Overseen ByKevin Liou, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Memorial Sloan Kettering Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores two music-based treatments to reduce anxiety in people with advanced cancer. One method, AI-Assisted Collaborative Songwriting (ARTIST) Intervention, involves creating songs with a music therapist using an AI platform. The other, Time and Attention Matched-Music Listening (TAME), involves listening to music and discussing its background and culture. Researchers aim to determine which method best reduces anxiety and boosts social connection. This trial suits individuals with advanced cancer who have experienced anxiety symptoms for at least a month and are undergoing cancer treatment. Participants need access to an internet-connected device for the sessions. As an unphased trial, this study offers a unique opportunity to explore innovative treatments that could enhance emotional well-being and social connections.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that AI-assisted music therapy can lower anxiety and boost well-being. These music therapy tools adjust to a person's feelings, making them effective and safe. For instance, a review found that AI-generated music interventions effectively improve anxiety and other health issues. Another study discovered that music therapy works as well as traditional therapy in reducing anxiety for cancer patients.

The ARTIST intervention involves creating songs together to help people connect and process their experiences. Reports indicate that this type of therapy helps manage emotions and reduce stress without major side effects.

The TAME approach involves listening to music, focusing on its culture and history. Although less interactive, it safely explores music's calming effects without any reported negative outcomes.

Both music-based treatments are generally well-received and have shown positive results in past studies. The aim is to enhance emotional health without any physical risks.12345

Why are researchers excited about this trial?

Researchers are excited about these treatments for anxiety in cancer patients because they offer new ways to address emotional challenges. The AI-assisted collaborative songwriting (ARTIST) intervention is unique because it uses music therapy to foster social connections and help patients process their cancer experience through creating personalized songs. This approach encourages active engagement and personal expression, which is different from standard treatments like medication or talk therapy. On the other hand, the time and attention matched-music listening (TAME) focuses on passive music listening with educational discussions, providing a structured yet relaxing experience without requiring personal reflection. These innovative methods could offer more personalized and engaging alternatives to traditional anxiety treatments.

What evidence suggests that this trial's music-based treatments could be effective for reducing anxiety in cancer patients?

Research has shown that music therapy can be as effective as Cognitive Behavioral Therapy (CBT) in reducing anxiety for cancer survivors, with positive effects lasting for months after therapy ends. Music therapy has been linked to improved mood and quality of life for cancer patients. In this trial, participants may receive the AI-Assisted Collaborative Songwriting (ARTIST) program, which uses AI technology to create personalized songs, aiming to further reduce anxiety by promoting social connection. Another group in this trial will participate in the Time and Attention Matched-Music Listening (TAME) sessions, which involve passive music listening exercises. While traditional music therapies have produced mixed results, this AI-assisted method represents a promising new development in anxiety care.678910

Who Is on the Research Team?

KL

Kevin Liou, MD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Are You a Good Fit for This Trial?

This trial is for people who have cancer and are experiencing anxiety. There are no detailed inclusion or exclusion criteria listed, so most adults with cancer and anxiety may be eligible.

Inclusion Criteria

I have had anxiety symptoms for at least one month.
Greater than 6-month expected survival as judged by treating oncologist
Score of 10 or higher on Blessed Orientation-Memory-Concentration indicative of dementia
See 14 more

Exclusion Criteria

Diagnosis of bipolar disorder, schizophrenia, or substance abuse

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in either AI-assisted collaborative songwriting or time and attention matched-music listening to reduce anxiety

8 weeks
8 weekly sessions (virtual)

Follow-up

Participants are monitored for anxiety reduction and other outcomes

18 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • AI-Assisted Collaborative Songwriting (ARTIST) Intervention
  • Time and attention matched-music listening (TAME)

Trial Overview

The study compares two music-based treatments: one uses an AI-powered songwriting platform with a therapist, while the other involves listening to music and discussing it with staff. The goal is to see which approach better reduces anxiety.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: AI-assisted collaborative songwriting (ARTIST)Experimental Treatment1 Intervention
Group II: Time and attention matched-music listening (TAME)Active Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials
1,998
Recruited
602,000+

Drexel University

Collaborator

Trials
160
Recruited
48,600+

Citations

Music Therapy as Effective as CBT for Anxiety in Cancer ...

A clinical trial shows telehealth-based music therapy is as effective as CBT in reducing anxiety in cancer survivors, improving quality of ...

How Music Therapy Is Changing Anxiety Care for Cancer ...

In the study, music therapy reduced anxiety in cancer survivors as effectively as CBT, with benefits that lasted up to four months after therapy ...

The impact of music interventions on anxiety for adult ...

Conclusion. The meta-analytic results failed to demonstrate a positive effect on anxiety among adult cancer patients in treatment but may in part be attributed ...

Outcomes and experiences of an online Balance-Space ...

We found a significant reduction in participants' perceived pain levels following the music intervention when compared to the meditation intervention. This ...

Effects of music intervention on anxiety, depression, and ...

Conclusions Music intervention may be a beneficial tool for anxiety reduction and QoL among cancer patients receiving chemotherapy. More high-quality RCTs are ...

A Study of Music Therapy for Anxiety in People With Cancer

ARTIST intervention is designed to reduce anxiety by facilitating social connection and cognitive processing of cancer-related experience. The ...

Virtual AI-Assisted Music Therapy for Anxiety Symptoms in ...

Virtual AI-Assisted Music Therapy for Anxiety Symptoms in People with Advanced Cancer (VIRTUOSO). National Cancer Institute.

The application of AI-assisted music therapy tools in mental ...

The available evidence suggests that AI-assisted music therapy tools can support personalized interventions by adapting to users' emotional and psychological ...

AI-Assisted Music Therapy and Traditional Music Approach ...

This study aims to compare the effectiveness of AI-Assisted Music Therapy and Traditional Music Approach in reducing anxiety in advanced cancer patients, with ...

Artificial intelligence based music therapy intervention in ...

Artificial intelligence based music therapy intervention in cancer patients undergoing chemotherapy in oncology day care (MUSICC). Artificial intelligence based ...