Pavulon

Intubation (procedure), Intubation (procedure), General Anesthesia + 1 more

Treatment

4 FDA approvals

2 Active Studies for Pavulon

What is Pavulon

Pancuronium

The Generic name of this drug

Treatment Summary

Anecuron is a steroid medication that blocks nerve signals from reaching muscles. It is stronger than curare and has fewer side effects on the cardiovascular system and histamine release.

Pancuronium Bromide

is the brand name

image of different drug pills on a surface

Pavulon Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Pancuronium Bromide

Pancuronium

1990

4

Approved as Treatment by the FDA

Pancuronium, also called Pancuronium Bromide, is approved by the FDA for 4 uses including Intubation (procedure) and Intubation (procedure) .

Intubation (procedure)

Intubation (procedure)

Therapeutic procedure

General Anesthesia

Used in combination with other therapies

Effectiveness

How Pavulon Affects Patients

Pancuronium is a muscle relaxant, similar to curare, that works by blocking the chemical acetylcholine from attaching to nerve cells. It does not cause any sudden muscle movements like some other drugs, and does not have any hormonal or nerve-blocking effects.

How Pavulon works in the body

Nondepolarizing neuromuscular blocking agents block signals from the brain to the muscles by blocking the receptors that acetylcholine, a type of nerve signal, binds to. These drugs can be reversed with anticholinesterase agents.

When to interrupt dosage

The dosage of Pavulon is subject to the diagnosed condition, including smooth muscle relaxation preceding radiological techniques, Intubation (procedure) and Intubation (procedure). The dose likewise changes as indicated by the strategy of conveyance (e.g. Liquid or Solution - Intravenous) portrayed in the following table.

Condition

Dosage

Administration

Therapeutic procedure

, 1.0 mg/mL, 2.0 mg/mL

Intravenous, , Injection, solution - Intravenous, Injection, solution, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous

Intubation (procedure)

, 1.0 mg/mL, 2.0 mg/mL

Intravenous, , Injection, solution - Intravenous, Injection, solution, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous

General Anesthesia

, 1.0 mg/mL, 2.0 mg/mL

Intravenous, , Injection, solution - Intravenous, Injection, solution, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous

Intubation (procedure)

, 1.0 mg/mL, 2.0 mg/mL

Intravenous, , Injection, solution - Intravenous, Injection, solution, Solution - Intravenous, Solution, Liquid, Liquid - Intravenous

Warnings

There are 20 known major drug interactions with Pavulon.

Common Pavulon Drug Interactions

Drug Name

Risk Level

Description

Aclidinium

Major

The risk or severity of adverse effects can be increased when Pancuronium is combined with Aclidinium.

Azelastine

Major

Pancuronium may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Cimetropium

Major

The risk or severity of adverse effects can be increased when Pancuronium is combined with Cimetropium.

Eluxadoline

Major

The risk or severity of constipation can be increased when Pancuronium is combined with Eluxadoline.

Ethanol

Major

Pancuronium may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

image of a doctor in a lab doing drug, clinical research

Pavulon Novel Uses: Which Conditions Have a Clinical Trial Featuring Pavulon?

4 active studies are assessing the capability of Pavulon to facilitate Intubation (procedure), smooth muscle relaxation in preparation for radiological procedures and General Anesthesia.

Condition

Clinical Trials

Trial Phases

Intubation (procedure)

0 Actively Recruiting

Intubation (procedure)

0 Actively Recruiting

General Anesthesia

2 Actively Recruiting

Phase 4, Not Applicable

Therapeutic procedure

0 Actively Recruiting

Pavulon Reviews: What are patients saying about Pavulon?

3.3

Patient Review

1/24/2012

Pavulon for Additional Agent to Induce General Anesthesia

This congenital diaphramatic hernia treatment is okay. It's helped me some, but I still have symptoms.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about pavulon

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who makes Pavulon?

"Organon (India) Ltd. Medindia has price information on 3,117 generic drugs and 110,459 brands."

Answered by AI

What is Pavulon used for?

"Pancuronium bromide, sold under the brand name Pavulon among others, is a medication used as part of general anesthesia to help with tracheal intubation and to provide skeletal muscle relaxation during surgery."

Answered by AI

What is the drug pancuronium used for?

"Pancuronium bromide is a medication used to temporarily paralyze muscles. It is often used during anesthesia to help with breathing, and also after surgery to prevent pain."

Answered by AI

What is the generic name for Pavulon?

"Pancuronium is a medicine that is used to treat muscle spasms. It is a type of medication that is called a neuromuscular blocker. This means that it works by blocking the nerves that control the muscles."

Answered by AI

Clinical Trials for Pavulon

Image of Mount Sinai Hospital in Toronto, Canada.

Intubation Blades for C-Section

Any Age
Female
Toronto, Canada

Cesarean section under general anesthesia requires intubation (insertion of a tube through the mouth into the breathing pipe to support breathing during the surgery). A device called a video laryngoscope is used, which has a smooth, curved, or less curved component called 'a blade' that helps the doctor gently see the voice box and guide the breathing tube safely into place during anesthesia; it is not a sharp tool blade. There are two types of video laryngoscopes blades: a Macintosh- style blade with a gentle curve, approximately 90 degrees) and a hyperangulated blade (with a more pronounced curve). Although video laryngoscopes are safe and both types have been used for around 20 years, it is not known whether one type works better that the other in patients undergoing cesarean delivery under general anesthesia. Because general anesthesia is used in only a small proportion (about 5%) of all cesarean deliveries, research in this area is limited. The main purpose of the study is to assess if a study comparing these two types of blades in the obstetric population is feasible. This is also known as a feasibility study, which aims to test the study plan and determine whether enough participants will join a larger study and accept the study procedures. The results will be used as a guide for a larger study.

Waitlist Available
Has No Placebo

Mount Sinai Hospital