Intubation Blades for C-Section
(ANGLED Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine which type of video laryngoscope blade is more effective for intubating pregnant patients during a C-section under general anesthesia. A video laryngoscope assists doctors in placing a breathing tube. The trial compares two blade types: the Macintosh style with a gentle curve and the hyperangulated with a sharper curve. As a feasibility study, it assesses whether enough participants will join and if the study methods function effectively. Pregnant patients requiring an emergency or urgent C-section with a breathing tube are suitable candidates. As an unphased trial, this study allows participants to contribute to the improvement of medical procedures for future patients.
What prior data suggests that these intubation blades are safe for cesarean sections?
Research has shown that both hyperangulated and Macintosh-style blades have been safely used in medical settings for about 20 years. One study suggested that hyperangulated blades can ease intubation by reducing the number of attempts needed, thereby lowering the risk of complications. Another study found that these blades might also help prevent breathing problems in certain situations, leading to fewer negative outcomes.
For the Macintosh-style blade, research indicates it is effective and quick for intubation in many cases. Its widespread use in emergency and anesthesia care supports its safety and reliability.
Both blades are generally well-tolerated, with no major side effects commonly reported. Their long history of use in surgeries suggests they are considered safe options for intubation during cesarean sections.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores two different intubation blade styles used during C-sections, which could improve safety and efficiency. The Hyperangulated blade offers a unique angle that may provide better visibility and easier access to the airway, potentially reducing intubation complications. On the other hand, the Macintosh style blade is a widely used standard that serves as a benchmark for comparison. By investigating these two methods, researchers hope to identify which blade offers the safest and most effective option for intubating patients undergoing C-sections.
What evidence suggests that these intubation blades are effective for cesarean sections?
This trial will compare hyperangulated blades and Macintosh-style blades for intubation during cesarean sections. Studies have shown that both blade types effectively assist breathing during cesarean sections under general anesthesia. Research indicates that the hyperangulated blade achieves a high success rate on the first attempt, with one study showing a 96.2% success rate, and often requires fewer attempts. The Macintosh-style blade, widely used and effective in many situations, may not perform as well in some cases. Both blades have been used safely for many years, and evidence supports their effectiveness for breathing assistance during surgeries like cesarean deliveries.678910
Are You a Good Fit for This Trial?
This trial is for pregnant individuals scheduled for a C-section who will need general anesthesia with intubation. People may not be eligible if they have conditions that make intubation unsafe or are unable to participate as determined by the study team.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants are intubated using either a Macintosh style blade or a Hyperangulated blade during cesarean delivery under general anesthesia
Follow-up
Participants are monitored for airway-related morbidity, including minor oral or dental injuries and postoperative sore throat, with a follow-up call on postoperative day 3
What Are the Treatments Tested in This Trial?
Interventions
- Hyperangulated Blade
- Macintosh Style Blade
Trial Overview
The study compares two types of video laryngoscope blades—a Macintosh-style blade (gentle curve) and a hyperangulated blade (sharper curve)—to see which works better for placing breathing tubes during general anesthesia in C-sections. Participants are randomly assigned to one of the two groups.
How Is the Trial Designed?
2
Treatment groups
Active Control
Study patients in this arm will be intubated using a Macintosh style blade
Study patients in this arm will be intubated using a Hyperangulated style blade
Find a Clinic Near You
Who Is Running the Clinical Trial?
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Lead Sponsor
Citations
First-Attempt Intubation Success of Video Laryngoscopy in ...
Intubation success rate on first attempt was 96.2% in the GlideScope group and 93.4% in the C-MAC D-Blade group. hyperangulated ...
Techniques for Improving Video Laryngoscopy With a ...
When using the GlideScope hyperangulated blade, all 3 years of residents had lower intubation times compared to attending physicians and they ...
Cleveland Clinic-Led Research Concludes Video ...
8,429 eligible surgical procedures in 7,736 patients, demonstrated a significant reduction in the number of intubation attempts
Factors Influencing the Time of Intubation Using C-MAC D ...
Results The mean time to intubate was the least with 100-degree angulation in group C (19.60 ± 0.97) while the maximum time was in group A with 80-degree ...
Difficult and failed intubation in Caesarean general ...
There were 33 difficult intubations among 660 patients, Junior trainees performed about 90% of all intubations and 28 (84.8%) out of 33 difficult intubations.
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physiciansweekly.com
physiciansweekly.com/post/hyperangulated-video-laryngoscopy-beneficial-for-achieving-intubationHyperangulated Video Laryngoscopy Beneficial for ...
hyperangulated video laryngoscopy reduces the number of attempts needed to achieve intubation, according to a study
Techniques for Improving Video Laryngoscopy With a ...
This hyper-angulated shape usually requires the use of a correspondingly curved stylet, such as the GlideRite stylet, to guide the endotracheal ...
A comparison of two hyperangulated video laryngoscope ...
The higher FPAs of hyperangulated blades in DA may avoid desaturations and decrease adverse events in pediatric airway management.
How to get the best view for airway intubation with video ...
This video provides the features of the BESDATA BD-DF Reusable Video Laryngoscope, blade types and how to use it for airway intubation.
A comparison of two hyperangulated video laryngoscope ...
The higher FPAs of hyperangulated blades in DA may avoid desaturations and decrease adverse events in pediatric airway management.
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