Beetroot Juice for PTSD
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to understand why women with PTSD (post-traumatic stress disorder) face a higher risk of heart disease as they age. Researchers are testing whether beetroot juice can improve blood vessel health in women with PTSD. The trial includes two groups: one receiving beetroot juice and the other a placebo, which is a non-active juice. Women aged 18-40 who experience PTSD symptoms, with or without a diagnosis of major depression, may be suitable candidates for this study. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could enhance heart health in women with PTSD.
Do I need to stop taking my current medications for the trial?
You won't need to stop taking your psychiatric medications for this trial, but you must hold any over-the-counter medications for 24 hours before each testing visit. If you're on medications for PTSD or cardiovascular diseases, you may not be eligible to participate.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research has shown that beetroot juice is generally safe for consumption. Studies have found it well-tolerated for up to 28 days, with no harmful effects at the doses tested. Rich in nitrates, beetroot juice converts into nitric oxide in the body, helping to relax blood vessels and potentially lower blood pressure. This suggests beetroot juice could be a safe option for those considering participation in a clinical trial.12345
Why are researchers excited about this trial?
Unlike standard treatments for PTSD, which often involve medications like SSRIs and cognitive therapy, beetroot juice offers a unique approach by utilizing natural compounds found in beets. Researchers are excited about beetroot juice because it contains high levels of nitrates, which can enhance blood flow and may improve brain function. This potential to naturally support mental health through dietary means sets it apart from traditional pharmaceutical options. Additionally, as a natural beverage, beetroot juice may have fewer side effects compared to conventional medications, making it an appealing alternative for those seeking a more holistic treatment option.
What evidence suggests that beetroot juice might be an effective treatment for PTSD?
This trial will compare Beetroot Juice with a Placebo Juice. Studies have shown that beetroot juice can enhance blood vessel function, which is crucial for heart health. Research indicates that beetroot juice contains high levels of nitrates, which the body converts into nitric oxide. This nitric oxide relaxes and widens blood vessels, improving blood flow. Some studies have linked regular consumption of beetroot juice to lower blood pressure. These effects are promising for women with PTSD, who often face a higher risk of heart problems. Additionally, beetroot juice may boost exercise endurance and reduce fatigue by improving the body's oxygen utilization.16789
Who Is on the Research Team?
Ida-Arlaine Fonkoue, MD, PhD, MsCR
Principal Investigator
University of Minnesota
Are You a Good Fit for This Trial?
This trial is for women aged 18-40 who have experienced trauma, with or without PTSD. Participants must not be pregnant, breastfeeding, using hormonal contraceptives, or have major heart, vascular, digestive diseases, certain psychiatric conditions (like psychosis), or allergies to nitrates.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either beetroot juice or placebo to assess its effect on endothelial function
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Beetroot Juice
- Placebo Juice
Trial Overview
The study tests whether drinking beetroot juice can improve blood vessel function in young women with PTSD compared to a placebo juice. It aims to understand links between trauma and cardiovascular health.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Minnesota
Lead Sponsor
Citations
Role of Nitric Oxide (NO) in Endothelial Dysfunction ...
The study is also testing whether a dietary supplement called beetroot juice might help improve the function of blood vessels in women suffering from PTSD.
Dietary nitrate supplementation suppresses sympathetic ...
These results suggest that dietary nitrate supplementation could improve isometric exercise endurance in postmenopausal women through suppressing sympathetic ...
Moderate dose of dietary nitrate improves skeletal muscle ...
Available studies suggest that consuming approximately 500 mL of beetroot juice 2 to 3 h before exercise may enhance endurance and oxygen efficiency. However, ...
Effect of Beetroot Juice Supplementation on Aerobic ...
These findings indicate that beetroot juice consumption can reduce fatigue during prolonged exercise by improving oxygen utilization and energy efficiency, ...
Effects of Beetroot Supplementation on Recovery After ... - PMC
The existing evidence suggests that a short-term beetroot supplementation has the potential to accelerate recovery of functional measures and muscle soreness.
Nitric Oxide (NO) and Endothelial Dysfunction in Women ...
This study looks at how trauma and PTSD affect blood vessels in young women by testing whether the dietary supplement beetroot juice might help ...
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bbc.co.uk
bbc.co.uk/programmes/articles/3cXzs0QnVVqvcvfWZ06C1BC/can-beetroot-boost-your-brain-and-bodyCan beetroot boost your brain and body?
Recent research suggests that the naturally-occurring nitrate in vegetables such as beetroot and rocket can improve physical performance among athletes and may ...
The Effects of Bioactive Compounds on PTSD Treatment - PMC
The data for the review were collected using academic search systems PubMed and Google Scholar. The search terms used were: “Post-Traumatic Stress Disorder,” “ ...
The effect of dietary supplements on core temperature and ...
Nitrate derived from beetroot juice lowers blood pressure in patients with arterial hypertension: a systematic review and meta-analysis. Front Nutr 9 ...
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