Regulation of Cues for Prediabetes

(BALANCE Trial)

This trial focuses on a treatment program called Regulation of Cues (ROC), designed to help Latinas manage prediabetes. The program aims to prevent Type 2 Diabetes and assist with weight loss. ROC includes training to increase awareness of appetite and exposure to eating triggers, specifically adapted for Latina women. Hispanic/Latina women with a BMI between 30-45 and a prediabetes diagnosis might be suitable candidates. The trial aims to determine if this program can improve health outcomes for participants. As an unphased trial, it offers the opportunity to contribute to innovative research tailored for the Latina community.

If you are currently taking medications for weight loss or prediabetes, you cannot participate in this trial. The protocol does not specify about other medications, so it's best to discuss with the trial team.

Research has shown that the Regulation of Cues (ROC) treatment is generally easy for people to handle. In a study with veterans who had binge eating issues, ROC reduced their binge eating without causing significant side effects, indicating participants managed the treatment well. The program teaches awareness of hunger and fullness signals to help control eating habits. These methods have been tested in other situations and have shown positive results without serious side effects. While more research continues, current evidence suggests ROC is a safe choice for those considering joining the study.¹²³⁴⁵

Unlike typical treatments for prediabetes that focus on medication or lifestyle changes like diet and exercise, the Regulation of Cues (ROC) treatment takes a novel approach by specifically addressing appetite awareness and cue-exposure. Researchers are excited about ROC because it is tailored for Latinas with prediabetes, a group that may have unique cultural and behavioral factors influencing their condition. This method could potentially empower individuals by enhancing their ability to recognize and manage hunger cues, potentially leading to better long-term management of prediabetes without solely relying on medication.

Research has shown that the Regulation of Cues (ROC) treatment program, which participants in this trial will receive, can aid in weight loss and reduce the risk of developing Type 2 Diabetes. In a study comparing ROC to Cognitive Behavioral Therapy, ROC proved more effective in reducing binge eating, leading to better weight management. Another study found that ROC helps individuals become more aware of their appetite and manage their eating habits. This approach is specifically designed for Latinas with prediabetes. These methods have improved body mass index (BMI) and helped control weight, both crucial for managing prediabetes and preventing diabetes.¹²³⁵⁶