750 Participants NeededMy employer runs this trial

Peer Support for Opioid Use Disorder

(BRIDGE-SC Trial)

AK
MM
Overseen ByMarisol Miranda
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Prisma Health-Upstate
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to help people with Opioid Use Disorder (OUD) begin and maintain their treatment while preventing overdose deaths. Participants will either receive the usual care or additional support from a Certified Peer Support Specialist (someone with recovery experience) for up to six months. The trial will determine if this extra support improves treatment success. This study suits individuals diagnosed with OUD who are new patients at mobile health clinics in South Carolina. As an unphased trial, it offers a unique opportunity to contribute to innovative approaches in OUD treatment and support.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.

What prior data suggests that this Certified Peer Support Specialist Intervention is safe for patients with Opioid Use Disorder?

Research has shown that Certified Peer Support Specialists (CPSS) are well-received by individuals with opioid use disorder (OUD). Past studies have demonstrated that involving peers in treatment yields positive results without negative effects. For instance, one small study found that including peers in the program was safe, as no harmful events occurred. This indicates that the treatment is generally safe for participants.

Additional studies have found that peer support helps individuals remain engaged in treatment and begin medication for OUD. These findings highlight the positive effects of peer support without safety concerns. Overall, the evidence suggests that CPSS interventions are a safe option for those considering participation in a clinical trial for OUD support.12345

Why are researchers excited about this trial?

Researchers are excited about the Certified Peer Support Specialist (CPSS) Intervention because it adds a human element to the standard care for opioid use disorder, which typically includes medication-assisted treatments like buprenorphine. Unlike traditional treatments that focus on medical and pharmaceutical approaches, the CPSS intervention incorporates personal support from someone with lived experience of recovery. This peer support can provide emotional guidance and practical tips, potentially making the treatment process feel less isolating and more relatable for participants. By integrating this personal support into the early phases of treatment, the intervention aims to enhance engagement and adherence, which are crucial for successful long-term recovery.

What evidence suggests that the Certified Peer Support Specialist Intervention is effective for Opioid Use Disorder?

This trial will compare the effectiveness of a Certified Peer Support Specialist (CPSS) intervention with standard care for individuals with opioid use disorder (OUD). Studies have shown that a CPSS can significantly aid people with OUD. Research indicates that those working with peer support specialists are more likely to remain in treatment. For example, one study found that 77% of patients attended their first medication appointment when supported by a peer specialist. Another study demonstrated that peer support can help with starting and continuing medication for OUD. Working with someone who has experienced similar challenges can greatly impact recovery. Participants in this trial may receive either standard care or the CPSS intervention.12678

Are You a Good Fit for This Trial?

This trial is for adults age 18 or older who have been diagnosed with opioid use disorder and are new patients receiving medication treatment for OUD at mobile health clinics.

Inclusion Criteria

I am 18 years old or older.
* Have diagnosis of OUD
* New mobile health MOUD patient

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive MOUD initiation and retention support, including meeting with a Certified Peer Support Specialist (CPSS) for up to 24 weeks post-initiation

24 weeks
Weekly visits (in-person or virtual)

Follow-up

Participants are monitored for safety and effectiveness after treatment, including adherence to buprenorphine and frequency of opioid use

6 months
Monthly assessments

Extension/Long-term follow-up

Evaluation of the population impact and cost-effectiveness of the PSS on preventing fatal overdose

Long-term

What Are the Treatments Tested in This Trial?

Interventions

  • Certified Peer Support Specialist Intervention

Trial Overview

The study is testing whether support from a certified peer (someone with lived experience) can help people start and stay in opioid use disorder treatment, compared to usual care. Participants will be followed for six months.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Certified Peer Intervention SpecialistExperimental Treatment1 Intervention
Group II: Standard of CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Prisma Health-Upstate

Lead Sponsor

Trials
91
Recruited
47,500+

Clemson University

Collaborator

Trials
38
Recruited
8,200+

Citations

Emergency Department Peer Support Program and Patient ...

In this cohort study of patients treated for opioid overdose, OORP implementation was associated with an increase in MOUD initiation and a decrease in repeat ...

Building Retention and Initiation Through Delivery of Peer- ...

The goal of our study is to increase OUD treatment initiation and retention and maximize prevention of overdose deaths in underserved ...

Peer support for patients with opioid use disorder in the ... - PMC

Primary outcomes were attendance at first MOUD appointment, retention in treatment at 30 days, and length of time in addiction treatment. 77% of ...

Effectiveness of peer recovery support services on stages ...

This study systematically synthesized existing literature reporting the effectiveness of PRSS interventions on stages of the OUD treatment cascade.

Peer recovery specialist-delivered, behavioral activation ...

The primary effectiveness outcome was methadone retention at three-months post-intervention vs. a comparison cohort initiating methadone during the same time ...

The feasibility and safety of training patients in opioid ... - PMC

This pilot study demonstrates promise in utilizing peer interventionists to deliver a brief PRSS intervention with limited training and no reported negative ...

Impact of Peer Support After Opioid Overdose

Main Outcomes and Measures The primary outcome was medication for opioid use disorder (MOUD) initiation within 60 days of discharge. Secondary outcomes ...

Therapy and Peer Support for Patients Taking Medication ...

The study will evaluate the comparative effectiveness of two psychosocial approaches, Cognitive Behavioral Therapy and peer support through the use of Certified ...