Standard vs. Telemedicine Surveillance for Head and Neck Cancer

KZ
Nancy Lee, MD profile photo
Overseen ByNancy Lee, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Memorial Sloan Kettering Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Approved in 1 JurisdictionThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine which follow-up method is better for individuals with HPV-related head and neck cancer who show no signs of the disease after treatment. It compares traditional in-person check-ups, known as standard surveillance, with telemedicine, where patients connect with their healthcare team through video calls or phone from home. The study examines how each approach affects quality of life, health outcomes, costs, and satisfaction levels among doctors and patients. Individuals who recently completed treatment for HPV-associated cancer and show no evidence of disease may be suitable candidates for this trial. As an unphased trial, it offers a unique opportunity to contribute to research that could enhance future care options.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that telemedicine surveillance is safe for head and neck cancer patients?

Research shows that telemedicine is generally safe for patients with head and neck cancer. Studies have found that patients using telemedicine feel more in control of their health and can reduce clinic visits. This approach allows patients to stay at home while maintaining regular check-ins with their doctors through video or phone calls.

Although specific safety data from clinical trials for telemedicine in this context is lacking, its use for medical follow-ups has become more common and accepted, especially during the COVID-19 pandemic. This study does not test a new drug or treatment but rather a different way to monitor health after treatment. No major safety issues have been reported with telemedicine for follow-ups.12345

Why are researchers excited about this trial?

Researchers are excited about the trial comparing telemedicine surveillance to standard care for head and neck cancer because it could revolutionize how patients are monitored after treatment. Unlike traditional follow-up, which requires in-person visits and procedures at a clinic, telemedicine allows patients to stay at home and still receive comprehensive care through video conferencing and phone calls. This approach could make cancer surveillance more convenient and accessible, especially for those who live far from healthcare facilities or have mobility issues. By potentially reducing the need for frequent clinic visits, telemedicine might also help lower healthcare costs and improve patients' quality of life.

What evidence suggests that this trial's surveillance methods could be effective for HPV-associated head and neck cancer?

This trial will compare standard surveillance with telemedicine surveillance (tele-surveillance) for head and neck cancer. Research has shown that telemedicine benefits patients with head and neck cancer. Studies indicate that tele-surveillance increases patients' sense of control and reduces hospital visits. It also enhances health management through remote check-ups and online communication. Both patients and doctors express high satisfaction with telemedicine, which has been linked to fewer hospital trips. This suggests that tele-surveillance could effectively manage head and neck cancer.12367

Who Is on the Research Team?

Nancy Y. Lee, MD, FASTRO - MSK ...

Nancy Lee, MD

Principal Investigator

Memorial Sloan Kettering Cancer Center

Are You a Good Fit for This Trial?

This trial is for adults over 18 who've had HPV-related squamous cell carcinoma in the oropharynx, are now disease-free after treatment, and can give informed consent. They should be able to speak and read English fluently. Those treated more than 9 months ago or with incomplete response/recurrent disease aren't eligible.

Inclusion Criteria

I may have had a CT or MRI scan after treatment.
My scans show no cancer signs after radiation, confirmed by my cancer doctors.
I can care for myself but may not be able to do heavy physical work.
See 3 more

Exclusion Criteria

My cancer did not fully respond or came back after treatment, as shown on a PET/CT scan.
I finished my radiation and chemotherapy over 9 months ago.
I am in a head and neck cancer trial with specific follow-up requirements.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Surveillance

Participants undergo either standard in-person surveillance or tele-surveillance to monitor for disease progression

2 years
Regular visits (in-person or virtual)

Follow-up

Participants are monitored for safety and effectiveness after surveillance

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • Questionnaires
  • Standard surveillance
  • Telemedicine surveillance (tele-surveillance)
Trial Overview The study compares two ways of monitoring patients after treating HPV-associated head and neck cancer: standard in-person check-ups versus telemedicine (remote) check-ups. It will assess quality of life, health outcomes, costs involved, and satisfaction levels with remote surveillance.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Telemedicine surveillance (tele-surveillance)Experimental Treatment2 Interventions
Group II: Standard surveillanceActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Memorial Sloan Kettering Cancer Center

Lead Sponsor

Trials
1,998
Recruited
602,000+

Published Research Related to This Trial

The follow-up process for head and neck cancer (HNC) patients is currently inconsistent, with various guidelines leading to potentially unnecessary discomfort and costs, highlighting the need for standardized protocols.
This review synthesizes literature from 1980 to 2009 to provide evidence-based recommendations for effective post-treatment surveillance, including optimal follow-up intervals and imaging modalities, aimed at improving patient care and resource management.
Making sense of post-treatment surveillance in head and neck cancer: when and what of follow-up.Manikantan, K., Khode, S., Dwivedi, RC., et al.[2015]
In a study of 302 patients with advanced head and neck squamous cell carcinoma, the overall 5-year survival rate was 56%, indicating a significant challenge in long-term survival after treatment.
Routine follow-up for these patients primarily serves to evaluate treatment outcomes and provide emotional support, rather than significantly improving survival rates after recurrence or the development of new tumors.
Is routine follow-up useful after combined-modality therapy for advanced head and neck cancer?Cooney, TR., Poulsen, MG.[2021]
A retrospective analysis of head and neck cancer patients revealed that 98% found telephone consultations beneficial, with 30% preferring them over in-person visits, especially those who traveled long distances or had lower stage disease.
The study suggests that telephone consultations can effectively complement traditional face-to-face appointments, allowing for reduced hospital visits while ensuring continued patient follow-up, with 68% of patients expressing interest in maintaining this practice post-pandemic.
A review of telephone consultations for head and neck cancer follow up: a patient satisfaction survey.Stewart, R., Collins, L., Kerr, B., et al.[2021]

Citations

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Telemedicine for head and neck cancer surveillance in the ...The coronavirus disease 2019 pandemic has led to increased telemedicine visits. This study examines current preferences and barriers for telemedicine among ...
Evaluation of a remote monitoring app in head and neck ...Our app is user‐friendly, makes patients feel more in control and remote monitoring can reduce the frequency of outpatient follow‐up visits.
Role of telemedicine in head neck cancerMobile health-based interventions can help cancer survivors increase physical activity and improve rehabilitation services. Effective self-management skills can ...
a randomised controlled trial study protocol comparing cThis study protocol describes the aim to assess patient satisfaction and safety with telemedicine follow-up after treatment of (pre-)malignant ...
The Impact of AI-driven Remote Patient Monitoring on ...This review aimed to evaluate the applications of artificial intelligence (AI) in RPM for cancer patients, exploring its impact on patient outcomes.
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