Music Therapy for Oral Mucositis

JT
Overseen ByJonathan Tang, MT-BC, PhD
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: University of California, San Francisco
Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how music therapy can help manage pain from oral mucositis in children with cancer. Oral mucositis causes painful mouth sores, often after chemotherapy or stem cell transplants, and current pain relief options may have unwanted side effects or prove insufficient. The study involves interviews with children who have tried music therapy and their parents to understand their experiences and thoughts about using music for pain relief. Children aged 6-18 who have undergone music therapy and experienced oral mucositis may be suitable candidates for this trial. As an unphased trial, this study offers a unique opportunity to contribute to understanding music therapy as a beneficial pain management tool for children.

What prior data suggests that music therapy is safe for pediatric patients with oral mucositis?

Research has shown that music therapy is generally safe for managing pain, including pain from mouth sores caused by oral mucositis. Oral mucositis often affects children undergoing cancer treatment. Although specific studies on music therapy for this condition are limited, it offers a non-drug option that avoids medication side effects. This makes it an appealing choice for those seeking to manage pain without additional drugs. Overall, music therapy is well-tolerated, with no known negative effects reported in similar situations.12345

Why are researchers excited about this trial?

Researchers are excited about using music therapy for oral mucositis because it offers a non-invasive and drug-free approach to managing pain. Unlike traditional treatments such as mouth rinses, pain medications, and protective coatings, music therapy focuses on the psychological and emotional relief of pain, which can enhance overall well-being. This method could provide a soothing experience for children who suffer from oral mucositis, making the difficult process more bearable without the side effects that often accompany medication. By exploring how music can impact pain perception, researchers hope to uncover new ways to improve quality of life for patients.

What evidence suggests that music therapy might be an effective treatment for oral mucositis?

Research has shown that music therapy can lower anxiety and boost emotional well-being in cancer patients undergoing treatments like chemotherapy. Studies have found that music therapy significantly reduces anxiety in these patients. While direct evidence is lacking for music therapy's effect on pain from oral mucositis in children, it is known to reduce general pain and improve quality of life. This suggests it might be a helpful non-drug option for managing pain from oral mucositis, which causes painful mouth sores. Music therapy could offer a safe way to ease this discomfort without the side effects of medications. Participants in this trial will participate in an interview to discuss their experiences with oral mucositis and perceptions of music therapy.14567

Who Is on the Research Team?

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Wei Li Jonathan Tang, MT-BC, PhD

Principal Investigator

University of California, San Francisco

Are You a Good Fit for This Trial?

This trial is for children ages 6-18 with cancer who have had painful mouth sores (oral mucositis) and received music therapy. Participants must be able to communicate in English, and cannot join if they have significant hearing loss or developmental disorders that prevent participation.

Inclusion Criteria

My child has had music therapy and mouth sores.
My child is between 6 and 18 years old.
Phase 1: Able to communicate in English
See 1 more

Exclusion Criteria

Phase 1: Significant pre-existing hearing loss or impairment that would interfere with participation in the interventions
I do not have a developmental disorder that stops me from joining music activities or study tasks.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Interview

Parent-child dyads participate in semi-structured interviews about experiences with oral mucositis and perceptions of music therapy

1 day
1 visit (virtual)

Follow-up

Participants are monitored for safety and effectiveness after interviews

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Music Therapy

Trial Overview

The study is testing whether music therapy can help reduce mouth pain from oral mucositis in kids with cancer. Researchers will use interviews to gather feedback about the effects of music therapy as a non-drug option for pain relief.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Phase 1: InterviewExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials
2,636
Recruited
19,080,000+

Perloff Family Foundation

Collaborator

Citations

Music Therapy for Oral Mucositis Pain in Pediatric Patients

Music therapy may offer a promising non-pharmacologic adjunct for reducing pain, yet no studies

Effectiveness of music therapy in reducing the level ...

The three sessions of music therapy are significantly reducing the anxiety level of cancer patients undergoing chemotherapy (p < 0.001) in the intervention ...

Music Therapy for Pain Reduction for Pediatric Cancer ...

This clinical trial tests how well music therapy works for reducing pain for pediatric cancer patients with oral mucositis. Oral mucositis, is characterized ...

Therapeutic Interventions to Manage Oral Mucositis and Their ...

PBMT was associated with reduced mucositis severity and improvements in physical and emotional functioning [25]. These outcomes are especially relevant in head ...

Music Therapy for Oral Mucositis Pain in Pediatric Patients

Music therapy may offer a promising non-pharmacologic adjunct for reducing pain, yet no studies to date have specifically evaluated its use for oral mucositis ...

Photobiomodulation Therapy in Oral Mucositis and Potentially ...

Based on the outcomes of its selected studies, the authors were not in favour of utilising PBMT for the management of OM, due to the influence of genetic ...

Intraoral Photobiomodulation Device Safe, Reduces Oral ...

Patients receiving active photobiomodulation therapy experienced 70% (P = .042) and 36% (P = .046) relative reductions in severe oral mucositis ...