Conversational AI + Digital Reinforcements for Alcoholism
(MICA-ED Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new digital approach to reduce risky drinking habits. It combines a conversational AI called MICA, which offers motivational counseling, with weekly text message reminders to support personal goals and self-monitoring. Participants may be suitable if they frequently visit the emergency room, drink excessively, own a mobile phone, and read English. The trial compares this new method to standard care to determine its effectiveness. As an unphased trial, it provides a unique opportunity to explore innovative solutions for personal health improvement.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Research on the safety of digital tools like MICA is still developing. MICA, a type of artificial intelligence, offers personalized counseling sessions. Although specific data on side effects or safety issues with MICA is not available, tools like this are generally considered safe.
The trial also includes weekly text message reminders, a common and safe method to help people change behaviors. No known safety risks are associated with receiving text messages for counseling support.
This trial uses a digital method for counseling, which does not involve medications or physical treatments, typically resulting in fewer risks compared to drug trials. However, due to the lack of specific safety data for MICA, participants should share their experiences and any concerns during the trial.12345Why are researchers excited about this trial's treatments?
Researchers are excited about the new approaches to treating alcoholism with MICA and MICA+SMS because they offer innovative, tech-driven solutions. Unlike traditional methods like counseling or medication, MICA uses a generative AI-powered counseling agent to provide brief, personalized Motivational Interviewing sessions. This technology focuses on engaging the user and encouraging them to talk about change, promoting personal autonomy. The MICA+SMS option adds to this by providing ongoing support through weekly SMS messages, helping participants with self-monitoring and goal-setting based on their alcohol use. This combination of real-time AI interaction and continuous digital reinforcement is a novel way to support individuals in reducing alcohol consumption.
What evidence suggests that this trial's treatments could be effective for reducing risky drinking?
This trial will compare different approaches to support behavior change in individuals with alcoholism. Studies have shown that conversational AI, such as MICA, can be as effective as in-person therapy for facilitating behavior change. MICA employs a method called Motivational Interviewing, which helps individuals discover their own reasons for making changes. This method has succeeded in other areas, such as reducing anxiety and depression. In this trial, some participants will receive the MICA treatment alone, while others will receive the MICA+SMS treatment, which includes weekly text messages to maintain motivation. Research indicates that this combination can aid long-term behavior change by keeping individuals engaged and encouraging healthier choices.678910
Who Is on the Research Team?
Brian Suffoletto, MS MS
Principal Investigator
Stanford University
Are You a Good Fit for This Trial?
This trial is for adults visiting the Emergency Department who are at risk due to their drinking habits. Specific inclusion and exclusion criteria are not listed, but generally targets people with risky alcohol use.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive a MICA session in the ED and at 3 months, with weekly SMS boosters for 12 weeks in the MICA+SMS group
Follow-up
Participants are monitored for alcohol consumption and related outcomes at 3, 6, and 12 months
What Are the Treatments Tested in This Trial?
Interventions
- MICA
- TRAC
Trial Overview
The study tests if a digital counseling tool using AI (MICA) plus weekly supportive text messages (TRAC) can help reduce risky drinking compared to usual care in the Emergency Department.
How Is the Trial Designed?
3
Treatment groups
Experimental Treatment
Active Control
This condition includes the MICA ED session, a 3-month booster, and 12 weeks of weekly SMS messages supporting self-monitoring, goal-setting, and adaptive strategies. Messages are tailored based on reported alcohol use and goal commitment, offering encouragement, feedback, and harm-reduction messaging.
MICA is a generative AI-powered counseling agent that delivers brief Motivational Interviewing (MI)-consistent sessions, following the validated MI process (engagement, focusing, evoking, planning, and closing). It uses personalized prompts to promote autonomy and evoke change talk, ending with a session summary and satisfaction check. Participants will complete a MICA session (\~5-10 min) in the ED and at 3 months.
Standard ED care and as-needed referral to alcohol resources
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Collaborator
Citations
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4.
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researchgate.net/publication/402860316_Follow_the_Rules_or_Not_Community_Norms_and_AI-Generated_Support_in_Online_Health_Communities(PDF) Follow the Rules (or Not): Community Norms and AI- ...
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MICA
Maryland Institute College of Art (MICA) is a leader in the world of visual arts featuring undergraduate, graduate, and certificate programs.
Mica
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What is Generative AI?
Generative AI is artificial intelligence (AI) that can create original content in response to a user's prompt or request.
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In this McKinsey Explainer, we define what is generative AI, look at gen AI such as ChatGPT and explore recent breakthroughs in the field.
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