AI Mental Health Tool for Depression

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Slingshot AI
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests an AI chat tool called Ash to determine if it reduces depression symptoms more effectively than traditional psychoeducation (informational materials about mental health). Participants will either use Ash or receive psychoeducation for four weeks, after which everyone will use Ash for several months. Researchers aim to discover if Ash not only alleviates depression but also improves anxiety, sleep, and stress. The trial seeks new users of the Ash app who live in the U.S. and have moderate depression symptoms. As an unphased trial, this study provides a unique opportunity to explore innovative mental health support through cutting-edge technology.

What prior data suggests that this AI mental health tool is safe for users?

Research has shown that AI tools like Ash can improve mental health by reducing loneliness and increasing social support. However, safety remains a crucial consideration. Some individuals have experienced worsening symptoms after discontinuing AI mental health apps, suggesting that consistent use might be necessary to maintain benefits.

AI tools for mental health, such as Ash, should adhere to clear safety guidelines to protect users. These guidelines include features like crisis detection and data privacy. Although Ash incorporates these features, the overall safety of AI tools in mental health continues to be studied.

For those considering participation in a trial with Ash, it is important to know that the focus remains on ensuring the tool's safety and effectiveness. As with any new treatment, staying informed and discussing any concerns with a healthcare provider is essential.12345

Why are researchers excited about this trial?

Unlike traditional treatments for depression, which often involve medication or in-person therapy sessions, Ash is an AI-driven mental health tool that offers a new way to support individuals. Researchers are excited about Ash because it provides users with a conversational AI experience that is available anytime, offering flexibility and accessibility that standard treatments may lack. Additionally, Ash empowers individuals to engage with mental health support on their own terms, potentially improving adherence and outcomes. This approach has the potential to complement existing methods by providing continuous support and intervention whenever needed.

What evidence suggests that the AI mental health tool Ash is effective for reducing depression symptoms?

Research has shown that Ash, a chat-based AI tool, can help reduce anxiety and depression symptoms. In this trial, some participants will receive free access to Ash for 9 months. A study from Stanford found that tools like Ash can lower anxiety symptoms in just a few weeks. Users of Ash have reported feeling less lonely and more socially supported. Ash provides a safe and private space for discussing worries and stress, which may prevent these feelings from worsening over time.46789

Who Is on the Research Team?

CS

Caitlin Stamatis, PhD

Principal Investigator

Slingshot AI

DH

Derrick Hull, PhD

Principal Investigator

Slingshot AI

Are You a Good Fit for This Trial?

This trial is for adults with at least moderate depression symptoms who are new users of the Ash mental health app. All activities are online, and participants must be able to complete surveys over several weeks.

Inclusion Criteria

Residents of the United States
New Ash users with active accounts at the time of recruitment
English-speaking
See 4 more

Exclusion Criteria

ASRM total score >= 6 at screening indicating positive screen for mania
PRIME-5 positive at screening defined as >= 1 item rated 6 or >= 3 items rated 5 indicating positive screen for psychosis-spectrum symptoms
Self-reported heavy episodic drinking weekly or more often on NIAAA single-item alcohol screen in past 12 months
See 5 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Treatment

Participants receive either the Ash AI mental health tool or psychoeducational modules for 4 weeks

4 weeks
All activities conducted online

Follow-up

Participants are monitored for changes in symptoms and well-being at multiple timepoints

32 weeks
Surveys at Weeks 2, 4, 8, and 36

Open-label extension

Participants receive 9 months of free access to Ash after the initial 4-week period

9 months

What Are the Treatments Tested in This Trial?

Interventions

  • Ash
  • Brief Therapist-Delivered Telehealth

Trial Overview

The study compares two groups: one uses Ash, an AI chat tool for mental health support, while the other receives psychoeducation materials online. After 4 weeks, both groups get access to Ash. Progress is tracked through online surveys.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Ash (AI Mental Health Tool)Experimental Treatment1 Intervention
Group II: PsychoeducationActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Slingshot AI

Lead Sponsor

NYU Langone Health

Collaborator

Trials
1,431
Recruited
838,000+

Citations

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