20 Participants NeededMy employer runs this trial

KetoneIQ for Cognition

(TACTIK Trial)

MJ
Overseen ByMichael J Ormsbee, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Florida State University

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if a ketone supplement, KetoneIQ®, can improve cognitive function and shooting accuracy under stress from intense exercise. Researchers will compare the supplement's effects to a placebo, which contains no active ingredient. They seek to understand if the supplement can maintain or enhance performance during physical challenges. Ideal participants are healthy SWAT team members not currently on a low-carb diet or using similar supplements. As an unphased trial, this study provides a unique opportunity to contribute to understanding the potential benefits of ketone supplements in high-stress situations.

Is there any evidence suggesting that KetoneIQ® is likely to be safe for humans?

Research has shown that ketones, such as those in KetoneIQ®, are generally safe for use. Studies have examined their effects on mood and cognition, finding some positive outcomes without major safety concerns. For instance, one study found that ketone supplements might improve mood during stressful diet changes. Another study suggested they could increase brain energy and enhance cognitive speed, again without serious side effects. While these studies indicate that ketones can be safe for brain health, consulting a healthcare provider before trying any new supplement is always important.12345

Why are researchers excited about this trial?

KetoneIQ® is unique because it utilizes ketone bodies as a supplement to potentially enhance cognitive function. Unlike traditional treatments for cognitive issues, which often involve pharmaceuticals targeting neurotransmitters, KetoneIQ® provides an alternative energy source for the brain. Researchers are excited about its ability to supply ketones, which may improve brain energy metabolism and cognitive performance. This novel approach offers a different mechanism of action, potentially opening new avenues for cognitive health support.

What evidence suggests that KetoneIQ® might be an effective treatment for cognition under stress?

Research suggests that ketones might enhance brain function by directly supplying energy to brain cells. Some studies have shown that ketones can improve thinking skills, such as focus and mental clarity. For example, one study found that drinking a special oil with ketones helped people with mild memory problems. However, not all research agrees—some studies have found that ketone supplements don't always improve thinking skills, especially in athletes. Overall, while some evidence is promising, results can vary depending on the situation and the person. In this trial, participants will receive either KetoneIQ® or a placebo to evaluate its effects on cognition.46789

Who Is on the Research Team?

MJ

Michael J Ormsbee, PhD

Principal Investigator

Florida State University

Are You a Good Fit for This Trial?

This trial is for adults who are able to participate in physical exercise and marksmanship tasks. People with health issues that prevent safe participation or those unable to complete the study activities will not be included.

Inclusion Criteria

Active Member of an accredited Law Enforcement Special Weapons and Tactics Team (SWAT)
I am healthy enough to complete all required tests.

Exclusion Criteria

Following a low-carbohydrate ketogenic diet
Self-reported Pregnancy
Allergy to testing materials
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are randomized into two groups and complete the trial in a crossover manner with Exogenous Ketone Supplement and Placebo conditions

1 day per condition
2 visits (in-person)

Follow-up

Participants are monitored for changes in cognitive performance, marksmanship, and select biomarkers after treatment

1 day
1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • KetoneIQ®

Trial Overview

The study compares a ketone supplement called KetoneIQ® to a placebo, looking at how each affects thinking skills and shooting accuracy after intense exercise. Participants are randomly assigned to receive either the supplement or placebo.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: KetoneIQ®Experimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Florida State University

Lead Sponsor

Trials
234
Recruited
41,100+

Citations

Ketone-IQ

✨ Research suggests ketones may: Sharpen focus and cognitive performance by fueling neurons directly Improve mitochondrial efficiency and ...

Oxford Review - Ketones and Cognition

A 2020 study11 showed that it is not necessary to consume ketones for 2 weeks to see an improvement in cognitive abilities. Patients with type 2 ...

Keto for cognitive function in neurological diseases - Study ...

Keto can reduce seizures in people with refractory epilepsy and has been shown in preliminary studies to improve aspects of cognition in the elderly. Given that ...

Ketones for Brain Health, Neuroplasticity & Performance

Learn how ketones may support brain energy, neuroplasticity, cognitive performance and neurological recovery—and why they're gaining ...

A ketogenic oil drink improves measures of cognitive ...

... ketone intake could improve mild cognitive impairment. The study. In this six-month randomized controlled trial, 82 participants around 72 ...

Ketone salt supplements for cognition and mood during a ...

In this randomized controlled trial, supplementation with ketone salts attenuated negative moods during the early stages of a ketogenic diet.

Effects of Exogenous Ketones on Cognitive Function in ...

The study will also test whether a single dose of an exogenous ketone supplement can improve brain energy use and cognitive processing speed.

Ketones show promise in preventing cognitive decline and ...

These findings build on previous research showing that ketones can alleviate neurological and cognitive affects. As we age our brain naturally ...

Keto for cognitive function in neurological diseases - Study ...

Keto can reduce seizures in people with refractory epilepsy and has been shown in preliminary studies to improve aspects of cognition in the elderly.