KetoneIQ for Cognition
(TACTIK Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a ketone supplement, KetoneIQ®, can improve cognitive function and shooting accuracy under stress from intense exercise. Researchers will compare the supplement's effects to a placebo, which contains no active ingredient. They seek to understand if the supplement can maintain or enhance performance during physical challenges. Ideal participants are healthy SWAT team members not currently on a low-carb diet or using similar supplements. As an unphased trial, this study provides a unique opportunity to contribute to understanding the potential benefits of ketone supplements in high-stress situations.
Is there any evidence suggesting that KetoneIQ® is likely to be safe for humans?
Research has shown that ketones, such as those in KetoneIQ®, are generally safe for use. Studies have examined their effects on mood and cognition, finding some positive outcomes without major safety concerns. For instance, one study found that ketone supplements might improve mood during stressful diet changes. Another study suggested they could increase brain energy and enhance cognitive speed, again without serious side effects. While these studies indicate that ketones can be safe for brain health, consulting a healthcare provider before trying any new supplement is always important.12345
Why are researchers excited about this trial?
KetoneIQ® is unique because it utilizes ketone bodies as a supplement to potentially enhance cognitive function. Unlike traditional treatments for cognitive issues, which often involve pharmaceuticals targeting neurotransmitters, KetoneIQ® provides an alternative energy source for the brain. Researchers are excited about its ability to supply ketones, which may improve brain energy metabolism and cognitive performance. This novel approach offers a different mechanism of action, potentially opening new avenues for cognitive health support.
What evidence suggests that KetoneIQ® might be an effective treatment for cognition under stress?
Research suggests that ketones might enhance brain function by directly supplying energy to brain cells. Some studies have shown that ketones can improve thinking skills, such as focus and mental clarity. For example, one study found that drinking a special oil with ketones helped people with mild memory problems. However, not all research agrees—some studies have found that ketone supplements don't always improve thinking skills, especially in athletes. Overall, while some evidence is promising, results can vary depending on the situation and the person. In this trial, participants will receive either KetoneIQ® or a placebo to evaluate its effects on cognition.46789
Who Is on the Research Team?
Michael J Ormsbee, PhD
Principal Investigator
Florida State University
Are You a Good Fit for This Trial?
This trial is for adults who are able to participate in physical exercise and marksmanship tasks. People with health issues that prevent safe participation or those unable to complete the study activities will not be included.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are randomized into two groups and complete the trial in a crossover manner with Exogenous Ketone Supplement and Placebo conditions
Follow-up
Participants are monitored for changes in cognitive performance, marksmanship, and select biomarkers after treatment
What Are the Treatments Tested in This Trial?
Interventions
- KetoneIQ®
Trial Overview
The study compares a ketone supplement called KetoneIQ® to a placebo, looking at how each affects thinking skills and shooting accuracy after intense exercise. Participants are randomly assigned to receive either the supplement or placebo.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Supplement of study. KetoneIQ® dosed at 0.6g/kg body weight
Flavor, texture, color matched. Very low calorie.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Florida State University
Lead Sponsor
Citations
1.
facebook.com
facebook.com/hvmn/posts/not-everyone-gets-paid-to-thinkbut-if-you-do-what-you-fuel-your-brain-with-matte/1543911361103943/Ketone-IQ
✨ Research suggests ketones may: Sharpen focus and cognitive performance by fueling neurons directly Improve mitochondrial efficiency and ...
2.
deltagketones.com
deltagketones.com/blogs/tdeltas-direct/oxford-review-ketones-and-cognition?srsltid=AYCX9vJBixnymOCNcDrSwDhMdVw1iawD_8r8cQgzzYoH3VqGIQEosoA7Oxford Review - Ketones and Cognition
A 2020 study11 showed that it is not necessary to consume ketones for 2 weeks to see an improvement in cognitive abilities. Patients with type 2 ...
3.
examine.com
examine.com/research-feed/study/w9kqz1/?srsltid=AYCX9vJGenlSjtWOh6F3SQml_iXSWSAtPMU3ANUxb0OR9Z-EQoS7QUgtKeto for cognitive function in neurological diseases - Study ...
Keto can reduce seizures in people with refractory epilepsy and has been shown in preliminary studies to improve aspects of cognition in the elderly. Given that ...
4.
betterbrainandbody.com
betterbrainandbody.com/post/fueling-the-brain-why-ketones-are-gaining-attention-in-neurological-health-and-performanceKetones for Brain Health, Neuroplasticity & Performance
Learn how ketones may support brain energy, neuroplasticity, cognitive performance and neurological recovery—and why they're gaining ...
5.
examine.com
examine.com/research-feed/study/g985Gd/?srsltid=AYCX9vJS_Yue13FrUd4joZf9edHJoZHkyzG3K5zQVBzrDwkWAcLWiaV0A ketogenic oil drink improves measures of cognitive ...
... ketone intake could improve mild cognitive impairment. The study. In this six-month randomized controlled trial, 82 participants around 72 ...
6.
examine.com
examine.com/research-feed/study/0ObYZ1/?srsltid=AYCX9vI6h2ppqaeAqJIPwxtYkjFECTwXvIXHIUaV7q-CmO6zsOmCyXfNKetone salt supplements for cognition and mood during a ...
In this randomized controlled trial, supplementation with ketone salts attenuated negative moods during the early stages of a ketogenic diet.
Effects of Exogenous Ketones on Cognitive Function in ...
The study will also test whether a single dose of an exogenous ketone supplement can improve brain energy use and cognitive processing speed.
8.
news-medical.net
news-medical.net/news/20240531/Ketones-show-promise-in-preventing-cognitive-decline-and-neurodegeneration.aspxKetones show promise in preventing cognitive decline and ...
These findings build on previous research showing that ketones can alleviate neurological and cognitive affects. As we age our brain naturally ...
9.
examine.com
examine.com/research-feed/study/w9kqz1/?srsltid=AYCX9vK2Fgdu1X_YPuy2uiruMmDmofrhrC_E4ZwyHMPfUwxrEG9CYbKOKeto for cognitive function in neurological diseases - Study ...
Keto can reduce seizures in people with refractory epilepsy and has been shown in preliminary studies to improve aspects of cognition in the elderly.
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