Family Building Support for Cancer Survivors
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to assist female adolescent and young adult cancer survivors in making informed family-building decisions post-treatment. It provides a nurse-led program with personalized reproductive health education and coping strategies to address fertility and emotional challenges after cancer therapy. Participants will engage in four online sessions, either exploring the new program, called Nurse Navigator-Delivered Family Building Decision Support, or receiving standard educational materials. Women who have completed cancer treatment, face fertility risks, and have not yet started a family might be a good fit. As an unphased trial, this study offers participants the chance to explore innovative support programs that could significantly impact their family-building journey.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It focuses on decision-making support for family building after cancer treatment.
What prior data suggests that this behavioral program is safe for cancer survivors?
Research has shown that programs with nurse navigators, like the one in this trial, lead to positive results for cancer patients. Studies have found that these programs can increase patient satisfaction and enhance the overall experience with cancer care. Additionally, standardized nurse navigator programs are associated with better health outcomes, such as shorter hospital stays and improved decision-making.
No reports have directly linked negative effects to these programs, suggesting they are generally well-received by patients. This trial emphasizes support and education, which further reduces the likelihood of negative side effects. Overall, current evidence indicates that using nurse navigators in cancer care is safe.12345Why are researchers excited about this trial?
Researchers are excited about the Nurse Navigator-Delivered Family Building Decision Support because it offers a unique, personalized approach to helping cancer survivors make informed family-building decisions. Unlike standard educational materials, this method involves personalized reproductive health education tailored to individual cancer types and treatments, such as chemotherapy and radiation. It also integrates coping skills from Acceptance and Commitment Therapy (ACT) to help patients align decisions with their personal values, which can reduce decision-making stress. Additionally, it encourages patient activation strategies to engage survivors actively in their reproductive care, offering a more hands-on and supportive experience than traditional resources.
What evidence suggests that this nurse navigator-delivered program is effective for supporting family-building decisions in cancer survivors?
Research has shown that nurse navigator programs can greatly assist cancer survivors in making family-building decisions. In this trial, participants in the Nurse Navigator-Delivered Family Building Decision Support arm will receive personalized education and support for reproductive health. One study found that such programs increased referrals for fertility preservation by eight times. Nurse navigators help patients understand their fertility options and guide them to available resources. They also enhance patient involvement by offering personalized education and support for reproductive health. Studies have demonstrated that nurse navigators lead to better outcomes, such as more frequent attendance at follow-up visits. This suggests that these programs could effectively address fertility and family-building concerns after cancer treatment.678910
Who Is on the Research Team?
Caroline S Dorfman, PhD
Principal Investigator
Duke University
Are You a Good Fit for This Trial?
This trial is for female cancer survivors aged 18-39 (diagnosed between ages 15-39) who have finished treatment that could affect fertility or pregnancy, can speak and read English, haven't completed family building, and are able to join video sessions. Those with major vision, hearing, cognitive issues, or severe mental illness can't participate.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Intervention
Participants receive a nurse navigator-delivered behavioral program consisting of four videoconference sessions over 4-6 weeks, focusing on reproductive health education and coping strategies.
Follow-up
Participants are monitored for changes in knowledge, decisional conflict, self-efficacy, and reproductive-health-related distress.
What Are the Treatments Tested in This Trial?
Interventions
- Nurse Navigator-Delivered Family Building Decision Support
Trial Overview
The study compares a nurse-led program—four online sessions offering personalized reproductive health education and coping strategies—to standard survivorship education. Participants are randomly assigned to one of the two groups.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Four \~60-minute, weekly or biweekly videoconference sessions over 4-6 weeks. Components include: 1. Personalized, risk-based reproductive health education based on cancer type and treatment exposures (e.g., gonadotoxic chemotherapy, chest or uterine radiation, anthracyclines); review of fertility potential evaluation, assisted reproductive technologies, adoption pathways, and pregnancy health considerations (maternal/fetal risks, surveillance, co-management). 2. ACT-derived coping skills (values clarification, cognitive defusion, acceptance, committed action) to align decisions with personal values and reduce avoidance. 3. Patient activation strategies to promote engagement in risk-based reproductive care and informed decision-making. Includes between-session practice and brief home exercises.
NCI booklet "Facing Forward: Life After Cancer Treatment" provided at baseline; participants may receive referrals to survivorship supportive services as needed.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor
Citations
A Decision Aid Intervention for Family Building After Cancer
This study presents the steps taken to develop a prototype for a patient resource for young women who have completed treatment for gonadotoxic cancer.
shared decision-making and the essential role of nurses
Their coordinated efforts enhance awareness of fertility preservation options, improve access to services, and support better patient outcomes.
(PDF) Impact of a Nurse Navigator Program on Referral ...
Dedicated nurse navigator programs have demonstrated substantial effectiveness, with one institution reporting an eightfold increase in fertility preservation ...
Addressing Barriers to Fertility Preservation for Cancer ...
The navigator ensures that patients are: (1) well-informed about the potential impact of cancer on fertility and FP options, (2) aware of available resources ( ...
Impact of a Nurse Navigator Program on Referral Rates and ...
A Nurse Navigator Program facilitates the referral pathway for patients with a cancer diagnosis interested in fertility preservation and results in higher ...
The nurse pivot-navigator associated with more positive ...
The NN role is significantly related to enhanced cancer care experiences and higher patient satisfaction.
7.
jons-online.com
jons-online.com/issues/2015/december-2015-vol-6-no-6/cancer-survivorship-the-role-of-the-nurse-navigatorCancer Survivorship: The Role of the Nurse Navigator
Data from the American Cancer Society reveal that the 5-year relative cancer survival rates have increased from 49% (1975-1977) to 68% (2004-2010), marking a ...
The nurse navigator: An evolving model of care
This opinion piece describes the role of the nurse navigator as a forward step in the evolution of nursing models of care.
9.
researchgate.net
researchgate.net/publication/49762905_Effects_of_Nurse_Navigators_on_Health_Outcomes_of_Cancer_PatientsEffects of Nurse Navigators on Health Outcomes of Cancer ...
This study provides evidence that standardized nurse navigator programs can improve patient outcomes in cancer care. Positive outcomes of the reduced length of ...
10.
patientnavigation.com
patientnavigation.com/files/Shared-Decision-Making-Practical-Implementation-for-the-Oncology-Team.pdfShared-Decision-Making-Practical-Implementation-for-the ...
The MMC Cancer Institute patient navigation program is designed to be a decision-support program in which nurse navigators are neutral advocates for patients.
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