Academic Detailing for Rheumatoid Arthritis

Not yet recruiting at 1 trial location
BN
AS
Overseen ByAaron S Kesselheim, MD, JD, MPH
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Brigham and Women's Hospital
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if educational visits to doctors, known as Academic Detailing, can encourage the prescription of more biosimilar medications (similar but cheaper versions) of adalimumab for rheumatoid arthritis. Researchers seek to discover whether in-person visits are more effective than virtual ones. Doctors who have written at least seven prescriptions for adalimumab and are actively practicing in the US may be suitable participants. The trial compares doctors who receive these educational visits to those who do not, assessing any changes in prescribing habits. As an unphased trial, this study provides a unique opportunity to understand how educational strategies can influence healthcare practices.

Do I need to stop my current medications to join the trial?

The trial does not specify whether you need to stop taking your current medications.

What prior data suggests that this educational outreach method is safe?

Research has shown that academic detailing, a one-on-one educational session for healthcare providers, is generally well-received. This method educates doctors about prescribing biosimilar medications, which closely resemble original biologic treatments but usually cost less.

Specific safety data for academic detailing does not exist because it is an educational activity, not a medical treatment. However, studies have found that academic detailing can successfully change how doctors prescribe medications without any reported negative effects. This suggests it is a safe way to influence healthcare practices. Participants can feel assured that these educational sessions do not pose any risk to their health.12345

Why are researchers excited about this trial?

Researchers are excited about Academic Detailing for Rheumatoid Arthritis because it offers a fresh approach to managing this condition. Unlike traditional treatments that focus on medications like methotrexate and biologics, Academic Detailing emphasizes personalized education for healthcare providers. This method aims to enhance the understanding and implementation of the best treatment practices through either in-person or virtual sessions. By potentially improving how current treatments are administered and followed, this technique could lead to better patient outcomes and more effective use of existing therapies.

What evidence suggests that academic detailing is effective for changing prescribing habits in rheumatoid arthritis?

Research has shown that educational outreach, known as academic detailing, can greatly improve how doctors prescribe medications. In studies with little bias, 69% reported significant improvements in at least one prescribing habit. This trial will compare an intervention group, which will receive academic detailing sessions, with a control group that will not. The goal is to determine if academic detailing can effectively guide doctors in prescribing medications, such as biosimilars. For people with rheumatoid arthritis (RA), advanced treatments have been proven to slow the disease and ease symptoms, which is the goal when prescribing effective biosimilar treatments. Overall, academic detailing has a strong history of improving prescription practices and can lead to better health outcomes for RA patients.26789

Are You a Good Fit for This Trial?

This trial is for clinicians who prescribe biologics to treat conditions like rheumatoid arthritis, psoriasis, and inflammatory bowel disease. It's not specified who can't join the trial, but it's implied that those not prescribing these medications would be excluded.

Inclusion Criteria

I wrote 7+ adalimumab prescriptions filled by Humana Medicare Part D patients in 2025.

Exclusion Criteria

Not able to identify active clinical practice in the US (50 states plus Washington DC)
I am retired.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Clinicians are offered an educational outreach visit about biosimilars, either in-person or virtually, depending on their geographic region

4-6 weeks
1 visit (in-person or virtual)

Follow-up

Participants are monitored for changes in prescribing behavior and the use and cost of biologics and biosimilars

12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Academic Detailing
Trial Overview The study tests if educational outreach visits to clinicians can increase prescriptions of biosimilar adalimumab. Clinicians will be randomly chosen to receive an academic detailing session or standard insurance plan outreach to compare the effects on their prescribing habits.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment2 Interventions
Group II: ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Brigham and Women's Hospital

Lead Sponsor

Trials
1,694
Recruited
14,790,000+

Humana Healthcare Research, Inc.

Collaborator

Trials
2
Recruited
15,600+

Citations

Rheumatology Informatics System for Effectiveness (RISE) ...Measures related to RA functional status and disease activity assessment had the greatest improvements over time (8.4% and 13.0% increase per year, respectively ...
Standardizing health outcomes for people with rheumatoid ...Given the lack of HODs for Rheumatoid Arthritis (RA), the aim of this study was to review published RA outcome descriptions and map them to the HOD framework.
Academic Detailing Interventions and Evidence-Based ...Among 36 studies deemed to have the lowest risk of bias, 25 (69%) showed significant improvements in at least 1 prescribing behavior, and the ...
A Real-World Effectiveness Study Using a Mobile ...Advanced therapies for the treatment of rheumatoid arthritis (RA) have helped to slow disease progression, decrease the signs and symptoms of ...
Rheumatology Informatics System for Effectiveness: A ...Examples of quality measures include that 55.2% had a disease activity score recorded, 53.6% a functional status score, and 91.0% were taking a ...
Patient perceptions of an electronic-health-record-based ...The study aimed to evaluate patient perceptions and attitudes towards the implementation of a novel patient-facing dashboard during clinical visits using a ...
Machine Learning Applied to Patient‐Reported Outcomes to ...ML methods coupled with longitudinal PRO data appear useful and can achieve reasonable accuracy in classifying LDA among patients starting a new biologic.
Survival Outcomes and Prognostic Factors in Rheumatoid ...This study highlights the importance of long-term b/tsDMARD intervention in RA patients, with observed low mortality and high survival rates.
Digital health technologies and machine learning augment ...Digital health technologies and machine learning augment patient reported outcomes to remotely characterise rheumatoid arthritis. Andrew P.
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