Aerobic Activity + CBT for Depression

This trial aims to determine if aerobic exercise immediately before cognitive behavioral therapy (CBT) enhances CBT's effectiveness for individuals with Major Depressive Disorder (MDD). Participants will either exercise or rest while watching a nature documentary before each of their 8 weekly CBT sessions. The trial seeks adults diagnosed with MDD who currently experience mild or higher depressive symptoms and have never undergone structured CBT. As an unphased trial, this study provides a unique opportunity to explore innovative treatment combinations for MDD.

If you are on a stable mental health medication regimen, you are encouraged to maintain it during the 8-week intervention period. If you are not currently taking any mental health medications, you can still participate.

Research has shown that aerobic exercise is generally safe and manageable for most people. Studies have found that activities like walking, jogging, and yoga can help reduce depression symptoms. Adding exercise to therapy could be beneficial without causing major side effects.

One study discovered that even minimal exercise can lower the risk of developing depression. This finding suggests that physical activity is not only safe but can also improve mental health over time.

Researchers are excited about the Aerobic Activity + CBT approach for depression because it combines physical exercise with therapy in a novel way. Unlike traditional treatments that often rely solely on medication or therapy alone, this method integrates 30 minutes of aerobic activity before cognitive behavioral therapy (CBT), potentially enhancing the effectiveness of the therapy. The physical exercise may help boost mood and cognitive function even before the therapy session begins. Additionally, the CalmCBT arm provides a unique comparison by incorporating a restful period with a nature documentary before therapy, offering insights into how different preparatory activities might influence therapeutic outcomes.

Research has shown that aerobic exercise can greatly reduce symptoms of depression. One study found that aerobic exercise had a moderate impact on lowering depression levels, with participants noticing improvements. Another review highlighted that both aerobic exercise and yoga helped reduce depressive symptoms by decreasing negative thoughts. Additionally, aerobic exercise is linked to better overall fitness, which can also boost mood. In this trial, one group of participants will complete 30 minutes of aerobic activity before cognitive behavioral therapy (CBT), potentially enhancing the therapy's effectiveness in treating depression.²³⁶⁷⁸