Sleep Pattern Changes for ADHD
(AACT Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how changes in sleep patterns affect adolescents with ADHD, focusing on their attention and overall functioning. Participants will adjust their sleep schedules over three weeks to assess the impact of both sleep duration and timing. The trial includes two sleep conditions: one where sleep aligns with their natural tendencies (aligned sleep extension) and another where it does not (misaligned sleep extension). Teens diagnosed with ADHD who typically go to bed late or wake up early might be suitable candidates. The research aims to determine if the timing of sleep is as important as the amount of sleep. As an unphased trial, this study offers participants the chance to contribute to groundbreaking research on sleep and ADHD.
What prior data suggests that these sleep pattern changes are safe for adolescents with ADHD?
Research has shown that more sleep can benefit children with ADHD. One study found that increasing sleep improved impulse control by 13%. This suggests that adequate sleep might help manage ADHD symptoms.
When sleep times align with a child's natural sleep pattern, known as aligned sleep extension, children with ADHD tend to sleep better. More children became good sleepers after increasing their sleep, indicating that this approach is well-received.
Conversely, if sleep times do not align with natural patterns, called misaligned sleep extension, ADHD symptoms like inattention and emotional issues can worsen. However, extending sleep is considered safe, primarily affecting symptom management rather than causing harm.
Overall, these sleep changes are safe and might help manage ADHD symptoms, though their effectiveness depends on how well the sleep schedule fits a child's natural sleep rhythm.12345Why are researchers excited about this trial?
Researchers are excited about these sleep pattern changes for ADHD because they explore how aligning or misaligning sleep schedules with an adolescent's natural body clock could impact ADHD symptoms. Unlike standard ADHD treatments that often involve medication like stimulants or behavioral therapy, this approach focuses on optimizing sleep duration and timing. By allowing 9.5 hours of sleep tailored to fit or deliberately misalign with an individual's natural sleep preference, researchers hope to uncover new insights into how sleep affects ADHD, potentially offering a non-pharmacological way to manage symptoms.
What evidence suggests that this trial's sleep pattern changes could be effective for ADHD?
This trial will compare two sleep extension strategies for teenagers with ADHD: Aligned Sleep Extension and Misaligned Sleep Extension. Research has shown that more sleep can improve symptoms in teenagers with ADHD. In one study, children with ADHD who increased their sleep improved their ability to control impulsive actions by 13%, meaning they were better at stopping themselves from acting without thinking. Conversely, sleep that doesn't align with a person's natural sleep-wake cycle can worsen attention and behavior problems. Studies have found that sleep issues are linked to increased difficulties with attention and rule-following. Overall, getting enough sleep at the right times appears to help manage ADHD symptoms more effectively.26789
Who Is on the Research Team?
Dean Beebe, Ph.D.
Principal Investigator
Children's Hospital Medical Center, Cincinnati
Stephen Becker, Ph.D.
Principal Investigator
Children's Hospital Medical Center, Cincinnati
Are You a Good Fit for This Trial?
This trial is for healthy adolescents aged 13-17 who have been diagnosed with ADHD. Participants should not have other major health issues and must be able to follow different sleep schedules over three weeks.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Sleep Schedule
Participants follow a sleep schedule that fits their usual non-obligatory schedule
Short Sleep Condition
Participants sleep for 6.5 hours per night to assess the impact of reduced sleep
Sleep Extension Condition
Participants sleep for 9.5 hours per night with timing aligned or misaligned with their chronotype
Follow-up
Participants are monitored for changes in attention and emotional regulation
What Are the Treatments Tested in This Trial?
Interventions
- Aligned sleep extension
- Misaligned sleep extension
Trial Overview
The study tests how changing both the amount and timing of sleep affects attention, mood, and thinking in teens with ADHD. Participants try out short sleep, well-timed longer sleep, or poorly timed longer sleep across separate weeks.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
One of two variants on the timing of period of when there is an opportunity to get healthy/recommended sleep duration. Aligned sleep extension allows 9.5 hours/night in bed in a manner that is broadly a poor fit with an adolescent's chronotype (e.g., early-to-bed and early-to-rise schedule for a night owl).
One of two variants on the timing of period of when there is an opportunity to get healthy/recommended sleep duration. Aligned sleep extension allows 9.5 hours/night in bed in a manner that broadly fits with an adolescent's chronotype (e.g., early-to-bed and early-to-rise schedule for a morning lark).
Find a Clinic Near You
Who Is Running the Clinical Trial?
Children's Hospital Medical Center, Cincinnati
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator
Citations
Sleep interventions for children with attention deficit ...
For six of the seven outcomes, the effect sizes were small to moderate and the certainty of the evidence was low. For one outcome, sleep disturbances,
Behavioral Sleep Treatment in ADHD Across Child and ...
RCTs testing all five interventions found that they all resulted in significant improvements in parent-rated sleep problems, with three ...
Interventions for Children With ADHD Might Improve Sleep ...
The remaining outcome, sleep disturbances, had a moderate effect size of –0.49 standardized mean differences (95% CI, –0.65 to –0.33), with a ...
Effects of Sleep Extension on Inhibitory Control in Children ...
For children with ADHD, sleep extension improved inhibitory control by 13% overall.
Effectiveness of Exercise on Sleep Quality in Attention ...
The performed meta-analysis with data from 131 participants indicated that exercise showed a non-significant trend towards increasing objective sleep duration ( ...
Sleep dysregulation in ADHD children: a systematic review ...
The results showed that the total sleep time in the ADHD children was significantly shortened, wake after sleep onset was significantly ...
A Randomized, Double-Blind, Forced-Dose, Placebo ...
A greater proportion of patients were good sleepers (global PSQI score ≤ 5) at the end of the open-label extension (57.3%) than at baseline ( ...
8.
additudemag.com
additudemag.com/adhd-sleep-extension-helps-children/?srsltid=AfmBOoqhYCq1ACXfr0FYJbVO-6hGkL_x-1wZHAcc5hQ-h36SQWk-Bk5gADHD Sleep: Why Sleeping More Helps Children Control ...
Extended sleep improves inhibitory control in children with ADHD by 13%, according to a small study1 conducted by researchers at the University ...
9.
pure.psu.edu
pure.psu.edu/en/publications/adolescents-with-adhd-sleep-as-a-predictor-of-academic-and-organi/Adolescents with ADHD: Sleep as a Predictor of Academic ...
The current study examined the influence of pre-treatment daytime sleepiness and sleep hygiene on academic and organizational treatment outcomes in a randomized ...
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