BraveBot for Anxiety Disorders
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a digital tool called BraveBot, designed to assist young people undergoing exposure therapy for anxiety, OCD, or related issues. BraveBot is a computer program that guides users through therapy homework, offering support and monitoring progress. The researchers aim to determine if BraveBot facilitates therapy task completion and boosts confidence in managing anxiety. Young people aged 12-22, already participating in exposure-based cognitive behavioral therapy (CBT) for anxiety or OCD at specific clinics, may be suitable for this study. As an unphased trial, this study provides a unique opportunity for participants to contribute to innovative research that could enhance therapy experiences for others in the future.
What prior data suggests that BraveBot is safe for young people using CBT for anxiety?
Research has shown that digital tools like BraveBot are generally safe for users. BraveBot aids in exposure therapy, a common treatment for anxiety disorders, by allowing users to confront their fears in a controlled environment. It does not replace a therapist but supports the therapy process, making it low-risk.
A clinician supervises BraveBot's use, adding an extra layer of safety. If the system detects concerning language during a session, BraveBot can pause and notify the therapist. This safety feature ensures users receive support throughout their therapy. While specific studies on BraveBot's negative effects are lacking, its use in existing therapy practices suggests it is well-tolerated.
Overall, digital tools for mental health have proven safe and helpful when used correctly. BraveBot is part of this promising trend, aiming to make therapy more engaging and effective.12345Why are researchers excited about this trial?
Unlike traditional treatments for anxiety disorders, which often rely on medication or therapist-led exposure therapy, BraveBot offers a unique, tech-driven approach. BraveBot is a conversational assistant powered by advanced language models, providing real-time, structured coaching during exposure exercises. This innovative tool helps clarify tasks, encourages persistence, and prompts users about safety behaviors, enhancing the exposure experience. Researchers are excited about BraveBot because it could make therapy more accessible, consistent, and engaging, especially for young people who are comfortable with digital interactions.
What evidence suggests that BraveBot is effective for anxiety disorders?
Research has shown that digital tools like BraveBot, which assist with therapy homework, can reduce anxiety symptoms. In this trial, participants will join either the BraveBot-Assisted Exposure group or the Self-Guided Exposure group. A small study found that automated chatbots used for therapy effectively lower anxiety and improve well-being. Cognitive behavioral therapy (CBT) alone is already effective, with studies indicating it helps many people reduce anxiety. Adding tools like BraveBot could enhance these effects by providing real-time support during homework tasks. This support might help young people stay on track with their therapy and feel more confident in managing their anxiety.678910
Who Is on the Research Team?
Madelaine R Abel, PhD
Principal Investigator
Massachusetts General Hospital
Are You a Good Fit for This Trial?
This trial is for youth ages 12-22 who are getting therapy for anxiety, OCD, or related issues at outpatient clinics. Participants must be assigned exposure therapy homework by their therapist and use a phone or computer. The study excludes those not in this age range or not receiving such therapy.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Active BraveBot Period
Participants engage in exposure-based CBT with BraveBot support for up to 45 homework-reminder days
Follow-up
Participants are monitored for safety and effectiveness after the active BraveBot period
What Are the Treatments Tested in This Trial?
Interventions
- BraveBot
Trial Overview
The study tests BraveBot, a digital coach that helps young people with their 'face-your-fears' exposure therapy homework. Each time they do an assignment, it's randomly decided if they'll get support from BraveBot or do it on their own. The goal is to see if BraveBot makes exposures easier and more effective.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Exposure instances randomized to this condition are completed with BraveBot, an LLM-powered audio-to-audio conversational assistant that provides real-time, structured coaching: clarifying the assigned exposure and its rationale, collecting SUDS ratings, encouraging persistence, prompting about safety behaviors and 'white-knuckling' at mid-exposure check-ins, and guiding brief post-exposure reflection.
Exposure instances randomized to this condition are completed independently by the youth (standard self-guided homework), without BraveBot coaching; the youth then completes the same brief post-exposure survey.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts General Hospital
Lead Sponsor
Harvard University
Collaborator
Mclean Hospital
Collaborator
TheraLoop AI, Inc.
Collaborator
Citations
effects of collaborative care with cognitive behavioral therapy
We evaluated effects of cognitive behavioral therapy (CBT) on outcomes of patients with medication-resistant anxiety disorders using data from the Coordinated ...
Research Review: Evidence-based treatment of Anxiety ...
Effectiveness of the drugs in the treatment of generalised anxiety, panic disorder, or social anxiety ranged from d = 0.17 – 0.96 (larger is ...
A pilot study (Preprint) | Request PDF
Effectiveness of a fully automated mobile therapeutic versus general chatbot in reducing depression and anxiety and improving well-being: A pilot study ( ...
4.
northwestpediatricneuropsychology.com
northwestpediatricneuropsychology.com/how-anxiety-therapy-compares-to-other-treatments/How Does Anxiety Therapy Compare to Other Mental ...
Overall, both psychotherapy and medication can help reduce anxiety symptoms, with remission rates around 50–60% for both approaches in ...
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research-portal.uu.nl
research-portal.uu.nl/en/publications/long-term-outcomes-of-cognitive-behavioral-therapy-for-anxiety-re/Long-term Outcomes of Cognitive Behavioral Therapy for ...
After 12 months, effects were small to medium for generalized anxiety disorder and social anxiety disorder, large for PTSD, and not significant or not available ...
Anxiety disorders - Symptoms and causes
Learn the symptoms of this mental health condition, and ways to manage worry and fear that interfere with your daily activities.
Anxiety Disorders - National Institute of Mental Health (NIMH)
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Anxiety: Symptoms, types, causes, prevention, and treatment
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Anxiety
Anxiety disorders can often be addressed successfully with psychotherapy, alone or in combination with medication, and with lifestyle shifts. Cognitive ...
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It's normal to be anxious at times. It may be time to get help if anxiety attack is severe or when anxiety doesn't stop. Learn about anxiety ...
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