200 Participants NeededMy employer runs this trial

Home Monitoring for Interstitial Lung Disease

(RESPOND-ILD Trial)

ED
YL
Overseen ByYeji Lee
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, San Francisco
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to identify the most effective home monitoring tools for tracking interstitial lung disease (ILD) events. Participants will use various combinations of devices, such as a spirometer (to measure lung function), a pulse oximeter (to check blood oxygen), and a scale, to determine which setup is easiest to use and provides the best data. The trial seeks individuals diagnosed with specific types of ILD, like idiopathic pulmonary fibrosis, who can regularly use these devices at home. This study is part of the Home Monitoring in Patients with f-ILD initiative. As an unphased trial, it offers a unique opportunity to contribute to research that could enhance daily life for ILD patients.

What prior data suggests that these remote monitoring devices are safe for home use in patients with interstitial lung disease?

Studies have shown that home monitoring devices like spirometers (which measure lung function), pulse oximeters (which check oxygen levels), and scales (for weight) are generally safe. Spirometry is a common method for tracking lung health and is typically easy for patients to use. Pulse oximeters are widely used at home without major safety concerns. Scales provide a standard and safe way to measure weight.

The devices used in this study are non-invasive, meaning they do not enter the body and are unlikely to cause harm. Some individuals might find using these devices slightly uncomfortable at first, but they are not known to cause serious side effects. Since this study involves no medication or procedures that enter the body, the risk remains very low.

In summary, previous research and widespread use indicate that these home monitoring devices are safe for use.

Why are researchers excited about this trial?

Home monitoring for interstitial lung disease (ILD) is unique because it empowers patients to track their lung health from the comfort of their own homes. Unlike traditional treatments that often require frequent hospital visits for monitoring, this method uses devices like spirometers, pulse oximeters, and wireless scales to gather valuable health data remotely. Researchers are excited about this approach because it could lead to earlier detection of changes in lung health, prompt interventions, and ultimately improve patient outcomes. By utilizing technology to bring monitoring directly to patients, this trial aims to enhance convenience and potentially transform how ILD is managed.

What evidence suggests that this trial's remote monitoring devices could be effective for detecting clinically significant Interstitial Lung Disease events?

This trial compares different home monitoring approaches for interstitial lung disease (ILD). Participants will be randomized into one of four arms. Studies have shown that monitoring ILD from home can be effective and valuable. Remote tools like spirometry (a test to check lung function) and pulse oximetry (which measures oxygen levels) track ILD progression. Research indicates that these tools are safe and acceptable to patients, offering a promising way to manage the disease at home. Evidence also suggests that they can improve access to care and potentially enhance the quality of life for those with ILD.12345

Who Is on the Research Team?

EF

Erica Farrand, MD

Principal Investigator

University of California, San Francisco

Are You a Good Fit for This Trial?

This trial is for people diagnosed with interstitial lung diseases like pulmonary fibrosis or bronchopulmonary dysplasia. Participants need to be able to use home monitoring devices and follow study instructions.

Inclusion Criteria

ILD diagnosis based on multidisciplinary conference review, the diagnostic gold standard
My ILD subtype is one of the common types with known treatment data.
English or Spanish speaking
See 2 more

Exclusion Criteria

Patients who are acutely ill
I am able to understand and give my consent to participate.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks
1 visit (in-person)

Baseline

Initial in-person baseline visit to set up home monitoring devices and complete initial assessments

1 day
1 visit (in-person)

Remote Monitoring

Participants use home-based monitoring tools and complete ePRO questionnaires to assess changes in health status over 12 months

12 months
Weekly home monitoring, remote visits at Months 3, 6, and 9

Final Assessment

Final in-person visit at Month 12 to evaluate outcomes and complete study assessments

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the main study period

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Home Monitoring in Patients with f-ILD

Trial Overview

The study tests different combinations of at-home monitoring tools—such as spirometers, pulse oximeters, scales, and electronic symptom surveys—to see which are easiest and most acceptable for tracking lung disease events remotely.

How Is the Trial Designed?

4

Treatment groups

Experimental Treatment

Group I: Spirometry OnlyExperimental Treatment2 Interventions
Group II: Spirometer, Oximeter, and Scale (weight)Experimental Treatment4 Interventions
Group III: Spirometer and Scale (weight)Experimental Treatment3 Interventions
Group IV: Spirometer and OximeterExperimental Treatment3 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials
2,636
Recruited
19,080,000+

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator

Trials
3,987
Recruited
47,860,000+

patientMpower Ltd.

Industry Sponsor

Trials
9
Recruited
710+

Citations

Home Monitoring in Interstitial Lung Disease - PMC - NIH

We hypothesize home monitoring will be safe, effective and acceptable for patients with ILD and result in a 50% reduction in routine laboratory ...

Remote Patient Monitoring for Managing Interstitial Lung ...

Remote patient monitoring (RPM) is an effective approach to evaluating ILD trajectories. Our results indicate that RPM is a feasible, valuable, ...

REMOTE-ILD study: Description of the protocol for a ...

Daily home spirometry and pulse oximetry have been demonstrated to be safe and acceptable to patients with interstitial lung disease (ILD)

Transforming ILD Care Delivery With Remote Monitoring

Participants in this 12-month study will use home-based monitoring tools provided by the study and complete electronic patient-reported outcome (ePRO) ...

Home monitoring in interstitial lung diseases

Home monitoring in ILD has the potential to improve access to specialist care, reduce the burden on health-care systems, improve quality of life ...