Home Monitoring for Interstitial Lung Disease
(RESPOND-ILD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to identify the most effective home monitoring tools for tracking interstitial lung disease (ILD) events. Participants will use various combinations of devices, such as a spirometer (to measure lung function), a pulse oximeter (to check blood oxygen), and a scale, to determine which setup is easiest to use and provides the best data. The trial seeks individuals diagnosed with specific types of ILD, like idiopathic pulmonary fibrosis, who can regularly use these devices at home. This study is part of the Home Monitoring in Patients with f-ILD initiative. As an unphased trial, it offers a unique opportunity to contribute to research that could enhance daily life for ILD patients.
What prior data suggests that these remote monitoring devices are safe for home use in patients with interstitial lung disease?
Studies have shown that home monitoring devices like spirometers (which measure lung function), pulse oximeters (which check oxygen levels), and scales (for weight) are generally safe. Spirometry is a common method for tracking lung health and is typically easy for patients to use. Pulse oximeters are widely used at home without major safety concerns. Scales provide a standard and safe way to measure weight.
The devices used in this study are non-invasive, meaning they do not enter the body and are unlikely to cause harm. Some individuals might find using these devices slightly uncomfortable at first, but they are not known to cause serious side effects. Since this study involves no medication or procedures that enter the body, the risk remains very low.
In summary, previous research and widespread use indicate that these home monitoring devices are safe for use.
Why are researchers excited about this trial?
Home monitoring for interstitial lung disease (ILD) is unique because it empowers patients to track their lung health from the comfort of their own homes. Unlike traditional treatments that often require frequent hospital visits for monitoring, this method uses devices like spirometers, pulse oximeters, and wireless scales to gather valuable health data remotely. Researchers are excited about this approach because it could lead to earlier detection of changes in lung health, prompt interventions, and ultimately improve patient outcomes. By utilizing technology to bring monitoring directly to patients, this trial aims to enhance convenience and potentially transform how ILD is managed.
What evidence suggests that this trial's remote monitoring devices could be effective for detecting clinically significant Interstitial Lung Disease events?
This trial compares different home monitoring approaches for interstitial lung disease (ILD). Participants will be randomized into one of four arms. Studies have shown that monitoring ILD from home can be effective and valuable. Remote tools like spirometry (a test to check lung function) and pulse oximetry (which measures oxygen levels) track ILD progression. Research indicates that these tools are safe and acceptable to patients, offering a promising way to manage the disease at home. Evidence also suggests that they can improve access to care and potentially enhance the quality of life for those with ILD.12345
Who Is on the Research Team?
Erica Farrand, MD
Principal Investigator
University of California, San Francisco
Are You a Good Fit for This Trial?
This trial is for people diagnosed with interstitial lung diseases like pulmonary fibrosis or bronchopulmonary dysplasia. Participants need to be able to use home monitoring devices and follow study instructions.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline
Initial in-person baseline visit to set up home monitoring devices and complete initial assessments
Remote Monitoring
Participants use home-based monitoring tools and complete ePRO questionnaires to assess changes in health status over 12 months
Final Assessment
Final in-person visit at Month 12 to evaluate outcomes and complete study assessments
Follow-up
Participants are monitored for safety and effectiveness after the main study period
What Are the Treatments Tested in This Trial?
Interventions
- Home Monitoring in Patients with f-ILD
Trial Overview
The study tests different combinations of at-home monitoring tools—such as spirometers, pulse oximeters, scales, and electronic symptom surveys—to see which are easiest and most acceptable for tracking lung disease events remotely.
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Participants randomized to Arm 1 will perform home spirometry weekly by completing a spirometry maneuver (inhaling and exhaling through the device mouthpiece). Participants will also complete brief symptom questionnaires electronically throughout the study period.
Participants randomized to Arm 4 will perform home spirometry weekly by completing a spirometry maneuver (inhaling and exhaling through the device mouthpiece), measure oxygen saturation levels daily using a pulse oximeter, and measure their weight weekly using the wireless scale provided by the study. Participants will also complete brief electronic symptom questionnaires throughout the study period.
Participants randomized to Arm 3 will perform home spirometry weekly by completing a spirometry maneuver (inhaling and exhaling through the device mouthpiece) and will measure their weight weekly using the wireless scale provided by the study. Participants will also complete brief electronic symptom questionnaires throughout the study period.
Participants randomized to Arm 2 will perform home spirometry weekly by completing a spirometry maneuver (inhaling and exhaling through the device mouthpiece) and will measure oxygen saturation levels daily using a pulse oximeter. Participants will also complete brief electronic symptom questionnaires throughout the study period.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, San Francisco
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
patientMpower Ltd.
Industry Sponsor
Citations
Home Monitoring in Interstitial Lung Disease - PMC - NIH
We hypothesize home monitoring will be safe, effective and acceptable for patients with ILD and result in a 50% reduction in routine laboratory ...
Remote Patient Monitoring for Managing Interstitial Lung ...
Remote patient monitoring (RPM) is an effective approach to evaluating ILD trajectories. Our results indicate that RPM is a feasible, valuable, ...
REMOTE-ILD study: Description of the protocol for a ...
Daily home spirometry and pulse oximetry have been demonstrated to be safe and acceptable to patients with interstitial lung disease (ILD)
Transforming ILD Care Delivery With Remote Monitoring
Participants in this 12-month study will use home-based monitoring tools provided by the study and complete electronic patient-reported outcome (ePRO) ...
Home monitoring in interstitial lung diseases
Home monitoring in ILD has the potential to improve access to specialist care, reduce the burden on health-care systems, improve quality of life ...
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.