Iquix
Plague, Yersinia pestis, inhaled anthrax caused by Bacillus anthracis + 21 more
Treatment
1 FDA approval
3 Active Studies for Iquix
Treatment for
Plague
What is Iquix
Levofloxacin
The Generic name of this drug
Treatment Summary
Levofloxacin is an antibiotic used to treat various bacterial infections. It is 8 to 128 times more effective against both gram-negative and gram-positive bacteria than its predecessor, ofloxacin. This medication is a part of the third generation of fluoroquinolones, which are often referred to as "respiratory quinolones" due to their effectiveness in treating respiratory infections. Levofloxacin was approved by the FDA in 1996 and is also available in Canada and other South American countries.
Levaquin
is the brand name
Iquix Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Levaquin
Levofloxacin
1996
421
Approved as Treatment by the FDA
Levofloxacin, also known as Levaquin, is approved by the FDA for 1 uses like Pseudomonas Infections .
Pseudomonas Infections
Used to treat Nosocomial Pneumonia caused by Pseudomonas Infections in combination with Piperacillin
Effectiveness
How Iquix Affects Patients
Levofloxacin is an antibiotic that works by blocking the bacteria's ability to make new DNA, which stops it from reproducing. This drug usually requires only one or two doses a day, but can cause an abnormal heart rhythm in some patients, so it should be used carefully in people with other risk factors, like low potassium levels. It has been found to work against certain types of bacteria, as well as some other kinds of germs like Chlamydia and Legionella. It is possible for bacteria to become resistant to levofloxacin, but it is unlikely to become resistant to other kinds of antibiotics.
How Iquix works in the body
Levofloxacin is an antibiotic that fights bacteria by blocking two bacterial enzymes. These enzymes, called DNA gyrase and topoisomerase IV, help bacteria reproduce and survive. Levofloxacin stops these enzymes from working, which prevents the bacteria from dividing and growing. This leads to the death of the bacteria.
When to interrupt dosage
The measure of Iquix is contingent upon the recognized ailment, including Pseudomonas Infections, Abscess and Therapeutic process. The amount of dosage is contingent upon the technique of delivery outlined in the table below.
Condition
Dosage
Administration
Yersinia pestis
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Cystic Fibrosis
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Pseudomonas Infections
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Impetigo
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Wound Infection
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Community Acquired Pneumonia (CAP) caused by susceptible bacteria
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
furuncle
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Pyoderma
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Hospital acquired pneumonia
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Communicable Diseases
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Cellulitis
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Abscess
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Prostatitis
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Pseudomonas Infections
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Communicable Diseases
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Sinusitis
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Urinary tract infection
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Bacterial conjunctivitis
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Therapeutic procedure
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Plague
250.0 mg, 500.0 mg, 750.0 mg, , 5.0 mg/mL, 25.0 mg/mL, 15.0 mg/mL, 7.5 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 240.0 mg, 240.0 mg/mL
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral, Intravenous, Injection, solution, Injection, solution - Intravenous, Solution / drops - Ophthalmic, Solution / drops, Solution, Solution - Oral, Injection - Intravenous, Injection, Solution - Ophthalmic, Ophthalmic, Solution - Intravenous, Injection, solution, concentrate - Intravenous, Injection, solution, concentrate, Solution / drops - Topical, Respiratory (inhalation), Solution - Respiratory (inhalation), Topical
Warnings
Iquix has one contraindication, so its use should be avoided when faced with the conditions indicated in the table below.
Iquix Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Levofloxacin may interact with Pulse Frequency
There are 20 known major drug interactions with Iquix.
Common Iquix Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Levofloxacin.
Amiodarone
Major
The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Amiodarone.
Amitriptyline
Major
Levofloxacin may increase the QTc-prolonging activities of Amitriptyline.
Anagrelide
Major
The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Anagrelide.
Arsenic trioxide
Major
The risk or severity of QTc prolongation can be increased when Levofloxacin is combined with Arsenic trioxide.
Iquix Toxicity & Overdose Risk
Levofloxacin is low in toxicity, yet an overdose can lead to ataxia, drooping eyelids, decreased movement, difficulty breathing, shaking, and seizures. Treatment for an overdose should include emptying the stomach and providing supportive care. It may also be helpful to monitor the patient's heart rate and rhythm. Dialysis is not an effective way to remove levofloxacin from the body.
Iquix Novel Uses: Which Conditions Have a Clinical Trial Featuring Iquix?
Condition
Clinical Trials
Trial Phases
Bronchitis
0 Actively Recruiting
Wound Infection
0 Actively Recruiting
inhaled anthrax caused by Bacillus anthracis
0 Actively Recruiting
Prostatitis
0 Actively Recruiting
Cellulitis
0 Actively Recruiting
Pseudomonas Infections
0 Actively Recruiting
Pseudomonas Infections
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
Hospital acquired pneumonia
0 Actively Recruiting
Sinusitis
1 Actively Recruiting
Not Applicable
Yersinia pestis
0 Actively Recruiting
Plague
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Pyoderma
2 Actively Recruiting
Phase 2
Impetigo
0 Actively Recruiting
furuncle
0 Actively Recruiting
Community Acquired Pneumonia (CAP) caused by susceptible bacteria
0 Actively Recruiting
Urinary tract infection
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Iquix Reviews: What are patients saying about Iquix?
5
Patient Review
5/22/2008
Iquix for Ulcer of the Cornea of the Eye with Bacterial Infection
1
Patient Review
11/22/2009
Iquix for Ulcer of the Cornea of the Eye with Bacterial Infection
Patient Q&A Section about iquix
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is levofloxacin eye drops used for?
"Ophthalmic levofloxacin is used in the eye to treat bacterial infections of the eye. Ophthalmic levofloxacin works by killing bacteria. This medicine is available only with a prescription from your doctor."
Answered by AI
Is levaquin isotonic?
"This is a dilute solution of levofloxacin in 5% dextrose solution. It is non-pyrogenic and nearly isotonic."
Answered by AI
How to use eye drops?
"To use eye drops correctly, tilt your head back and look up. Use one hand to pull your lower eyelid down and away from your eyeball. This will form a pocket. Hold the eye drop bottle upside down in the other hand with the tip just above the pocket. Squeeze the prescribed number of drops into the pocket."
Answered by AI