Streetlab VR for AMD
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how well individuals with different stages of age-related macular degeneration (AMD) can read in dim light using a virtual reality tool called Streetlab VR. Researchers aim to determine if a connection exists between the eyes' adjustment to darkness and reading performance, focusing on the rod cells that assist with low-light vision. The study includes participants with early or intermediate AMD, geographic atrophy (a more advanced form of AMD), and healthy vision. Ideal candidates are at least 50 years old, can provide consent, and have not undergone previous eye surgeries or had conditions affecting vision tests. As an unphased trial, this study offers a unique opportunity to contribute to understanding AMD and its impact on vision.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the study team or your doctor.
What prior data suggests that Streetlab VR is safe for use in this study?
In a previous study, researchers examined Streetlab VR and found that most patients tolerated it well. No serious side effects occurred. The study included individuals with age-related macular degeneration (AMD) and aimed to test both safety and effectiveness. Although a slight decrease in retinal sensitivity occurred over time, it was not linked to any harmful effects. Overall, the treatment has not shown any major safety concerns in these studies.12345
Why are researchers excited about this trial?
Streetlab VR is unique because it uses virtual reality technology to help people with Age-related Macular Degeneration (AMD) improve their daily visual experiences. Unlike standard treatments, which often involve medications or injections, this approach offers a non-invasive method to enhance visual function. Researchers are excited about this trial because it could provide a new way to support patients with varying stages of AMD, including early AMD, intermediate AMD, and geographic atrophy, potentially improving their quality of life without the need for medical or surgical interventions.
What evidence suggests that Streetlab VR is effective for AMD?
Research has shown that Streetlab VR, the investigational treatment in this trial, might assist people with age-related macular degeneration (AMD) by enhancing their ability to read in dim light. AMD affects the eyes and can lead to vision loss, making it difficult to see in low lighting. Streetlab VR uses virtual reality to enhance vision. Although limited data exists on its effectiveness, the concept is based on AMD's impact on the eye's rod cells, which aid in night vision. Early results suggest it might help users adapt to dark environments, potentially making everyday tasks like reading easier.12567
Who Is on the Research Team?
Eleonora Lad, MD, PhD
Principal Investigator
Duke University
Are You a Good Fit for This Trial?
This trial is for adults over 50 with early to intermediate dry age-related macular degeneration or geographic atrophy, and healthy individuals as controls. Participants must be able to consent and have no conditions like dense cataracts, severe myopia, nystagmus, glaucoma requiring treatment, or any condition that could affect the study's procedures.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Single Visit Assessment
Participants undergo a comprehensive eye exam, rod-mediated dark adaptation measurement, reading performance assessment, and mobility test
Follow-up
Participants are monitored for changes in ellipsoid zone attenuation over time
What Are the Treatments Tested in This Trial?
Interventions
- Streetlab VR
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor
Boehringer Ingelheim
Industry Sponsor
StreetLab Vision
Industry Sponsor