This trial is no longer recruiting.My employer runs this trial

Contact Lenses for Visual Acuity

SC
Overseen ByStudy Contact
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Johnson & Johnson Vision Care, Inc.
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests how well different types of contact lenses improve clarity, particularly with varying levels of visual blur. The study compares two types of ACUVUE® OASYS lenses: the ACUVUE® OASYS 1-Day Sphere and the ACUVUE® OASYS Multifocal, to determine which performs better in various situations. Individuals who frequently wear soft contact lenses and have vision prescriptions within a specific range may qualify. As an unphased trial, it offers participants the chance to contribute to valuable research that could enhance vision correction options for many.

Will I have to stop taking my current medications?

If you are currently using any eye medications or have an eye infection, you cannot participate in the study. Also, if you have any allergies, diseases, or are taking medications that might interfere with wearing contact lenses, you may be excluded.

What prior data suggests that these contact lenses are safe for visual acuity studies?

Previous studies have found ACUVUE OASYS 1-Day Sphere lenses to be generally well-tolerated by users. Some individuals have reported minor issues such as eye discomfort, stinging, or tearing. These lenses also block harmful UV rays, helping to protect the eyes.

ACUVUE OASYS Multifocal lenses are considered safe, though some users might experience mild irritation or itching. Rarely, more serious reactions, such as severe allergic reactions, have been reported, but these are uncommon.

The FDA has approved both types of lenses for daily use, indicating they meet safety standards for contact lenses. As with any contact lenses, risks like infections or allergic reactions exist, so following the usage instructions carefully is important.12345

Why are researchers excited about this trial?

Researchers are excited about these contact lenses because they aim to improve visual acuity using innovative filtering techniques. Unlike standard contact lenses that primarily correct vision through lens curvature, these lenses incorporate a series of filters with varying thicknesses (ranging from 1/4mm to 2mm) to enhance visual clarity. This novel approach could provide a more tailored vision correction experience, potentially reducing eye strain and improving overall comfort for the wearer. By exploring different sequences of filter application, the trial seeks to determine the optimal combination for superior visual performance.

What evidence suggests that this trial's treatments could be effective for visual acuity?

This trial will evaluate the effectiveness of ACUVUE OASYS 1-Day Sphere and ACUVUE OASYS Multifocal contact lenses. Studies have shown that ACUVUE OASYS 1-Day contact lenses provide clear and comfortable vision, with 91% of users reporting consistently clear vision, especially when using digital devices. Additionally, 62% of patients preferred these lenses for overall vision clarity.

Extensive studies on ACUVUE OASYS Multifocal lenses indicate that 95% of users experienced improved vision for both near and far distances. These lenses are designed to assist people with presbyopia, a condition that makes close-up vision more difficult with age. Most users find them effective for everyday activities. Participants in this trial will be randomly assigned to different filter sequences to assess the impact on visual acuity with these lenses.678910

Who Is on the Research Team?

J&

Johnson & Johnson Vision Care, Inc. Clinical Trial

Principal Investigator

Johnson & Johnson Vision Care, Inc.

Are You a Good Fit for This Trial?

This trial is for adults aged 18–69 who regularly wear soft contact lenses in both eyes (at least 6 hours/day, 2 days/week), have mild to moderate vision correction needs (+3.00 to -5.00), low astigmatism (<1.00), and can see well with glasses (20/25 or better). Participants must be able to follow study instructions.

Inclusion Criteria

4. Habitually wear soft contact lenses (either spherical or multifocal) in both eyes in a daily reusable or daily disposable wear modality (i.e., not extended wear modality). Habitual wearer is defined as a minimum of 6 hours per day, for a minimum of 2 days per week during the past 30 days.
5. Possess a wearable pair of spectacles that provide correction for distance vision.
I am between 18 and 69 years old.
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants are evaluated for visual performance with different magnitudes of scatter over 3 visits

3 visits
3 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

2-4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • ACUVUE® OASYS 1-Day Sphere
  • ACUVUE® OASYS Multifocal

Trial Overview

The study compares two types of ACUVUE® OASYS contact lenses—Multifocal and 1-Day Sphere—to see how they affect vision under different light scatter conditions. Each participant will try both lens types during the study.

How Is the Trial Designed?

5

Treatment groups

Experimental Treatment

Group I: No filter/Filter 1/4mm/Filter 1/2mm/Filter 1mm/Filter 2mmExperimental Treatment2 Interventions
Group II: Filter 2mm/No filter/Filter 1/4mm/Filter 1/2mm/Filter 1mmExperimental Treatment2 Interventions
Group III: Filter 1mm/Filter 2mm/No filter/Filter 1/4mm/Filter 1/2mmExperimental Treatment2 Interventions
Group IV: Filter 1/4mm/Filter 1/2mm/Filter 1mm/Filter 2mm/No filterExperimental Treatment2 Interventions
Group V: Filter 1/2mm/Filter 1mm/Filter 2mm/No filter/Filter 1/4mmExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johnson & Johnson Vision Care, Inc.

Lead Sponsor

Trials
224
Recruited
26,100+
Top Products
- ACUVUE® disposable contact lenses - TECNIS® intraocular lenses - LASIK vision correction systems
Joaquin Duato profile image

Joaquin Duato

Johnson & Johnson Vision Care, Inc.

Chief Executive Officer since 2022

MBA from ESADE, Master of International Management from Thunderbird School of Global Management

Dr. Jijo James, MD profile image

Dr. Jijo James, MD

Johnson & Johnson Vision Care, Inc.

Chief Medical Officer since 2014

MD from St. Johns Medical College, MPH from Columbia University

Citations

Research highlights that the latest ACUVUE contact lens ...

Results showed that ACUVUE OASYS MAX 1-Day for ASTIGMATISM was consistently rated higher for overall opinion and all comfort metrics. When asked ...

New data demonstrate patient preference of Acuvue Oasys ...

Additionally, when the Oasys lens was worn after the dailies, positive feedback of overall opinion increased to 80% compared to 33.3% when the ...

Box of ACUVUE® OASYS 1-Day for ASTIGMATISM

91% of patients agreed ACUVUE ® OASYS 1‐DAY for ASTIGMATISM allowed them to experience clear, consistent vision while using digital devices. ¶,12. Also ...

J&J to Present New Data Demonstrating Superiority of ...

62% of patients preferred Acuvue Oasys Max 1-Day for overall vision, compared to just 18% who preferred Dailies Total1. When using digital ...

Johnson & Johnson to Present New Scientific Data on ...

This clinical study of 384 presbyopic patients wearing Acuvue Oasys Max 1-Day multifocal contact lens suggest that the benefit of correcting ...

Important Safety Information | ACUVUE® Contact Lenses

Do not wear contact lenses if you have an eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. If one ...

ACUVUE® OASYS 1-DAY with HydraLuxe® Contact Lenses

Built-in UV protection #. Features the highest classification of UV blocking available in contacts. # ...

MAUDE Adverse Event Report - accessdata.fda.gov

I have warn contacts for 20 years and was recently prescribed acuvue oasys 1-day with hydraluxe.My eyes immediately began to sting, water, ...

ACUVUE® OASYS 1-Day with HydraLuxe® Technology

#Helps protect against transmission of harmful UV radiation to the cornea & into the eye. ^WARNING: UV-absorbing contact lenses are NOT substitutes for ...

LENSES, SOFT CONTACT, DAILY WEAR - accessdata.fda.gov

I have worn contact lenses for almost 20 years, and have used the acuvue oasys daily lenses for about five years.