Anticoagulation Management for Cancer
(ACE-HIGH Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The purpose of this study is to help find how safe current practices are when managing blood thinners in people with cancer who are having surgery or medical procedures. Investigators will also measure how often bleeding or clotting problems happen in this setting. The goal is to use this information to improve future care and reduce these risks for patients. This study will determine whether contemporary practices can be safely applied to cancer patients, and also evaluate the blood thinner level left over in patient's body at the time of surgery.
Who Is on the Research Team?
Joseph Shaw, MD, MSc, FRCPC
Principal Investigator
Ottawa Hospital Research Institute
Are You a Good Fit for This Trial?
This trial is for adults with active or recently treated cancer who are taking certain blood thinners (like Apixaban, Rivaroxaban, Edoxaban, or Dabigatran) and need to temporarily stop these medications before having a planned surgery or procedure related to their cancer.Inclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- standardized perioperative anticoagulation management Guideline
Trial Overview
The study is testing the safety of current guidelines for managing blood thinners around the time of surgery in people with cancer. It tracks how often bleeding or clotting problems happen when following these practices.
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
The intervention consists of applying perioperative anticoagulation management strategies based on contemporary guidelines for non-cancer patients to a cancer population undergoing invasive procedures or surgery. This study is a pragmatic, guideline-informed interventional study. It does not involve testing a novel drug, biologic, or device, and therefore does not align with clinical trial phases (Phase I-IV).
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ottawa Hospital Research Institute
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.