Image-Informed Length Ureteral Stents for Ureteral Stent Syndrome
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests whether ureteral stents, custom-fit using images and known as image-informed length ureteral stents, are better tolerated than standard one-size-fits-all stents. The goal is to determine if personalized stents more effectively reduce discomfort after a procedure to manage kidney stones. Suitable participants have kidney stones requiring treatment with a ureteral stent and show no signs of a urinary tract infection. As an unphased trial, this study offers a chance to contribute to innovative research that could enhance comfort for future patients.
Do I have to stop taking my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. However, if you use chronic narcotics or are allergic to non-steroidal anti-inflammatory medications, you may not be eligible to participate.
What prior data suggests that these ureteral stents are safe?
Research has shown that ureteral stents, which keep the tube connecting the kidney to the bladder open, are generally safe for patients. One study found that stents made to fit the exact length of a patient's ureter were comfortable and caused fewer side effects. Another study found that both custom-length and adjustable-length stents worked well and were safe for ureter problems.
For adjustable-length stents, research indicates they are effective and safe in most cases. These stents can fit different ureter sizes, potentially reducing discomfort and other symptoms.
Overall, both types of stents are considered safe, with any side effects, such as discomfort, usually being mild.12345Why are researchers excited about this trial?
Researchers are excited about the image-informed length ureteral stent because it offers a personalized approach to addressing ureteral stent syndrome. Unlike standard ureteral stents, which come in fixed sizes, this innovative stent uses imaging technology to determine the precise length needed for each patient. This customization aims to reduce discomfort and complications by ensuring a better fit within the urinary tract. By potentially improving patient comfort and outcomes, this tailored method could represent a significant advancement in the treatment of ureteral stent syndrome.
What evidence suggests that this trial's treatments could be effective for ureteral stent syndrome?
Research has shown that ureteral stents improve urine flow and reduce blockages in the urinary tract. This trial will compare two types of stents: image-informed length ureteral stents and variable length ureteral stents. Studies have found that stents tailored to a person's specific ureter length, like the image-informed length stents in this trial, can be more comfortable than standard one-size-fits-all stents. Patients with these custom-length stents report fewer symptoms of bladder irritation. Meanwhile, stents with adjustable lengths, such as the variable length stents in this trial, offer advantages like longer usability and less discomfort than some other types. Both stent types in this trial aim to improve health outcomes by maintaining urine flow and reducing complications.12467
Who Is on the Research Team?
Luay Alshara, MD
Principal Investigator
Weill Medical College of Cornell University
Are You a Good Fit for This Trial?
This trial is for adults aged 18-80 who have kidney stones needing ureteroscopic treatment and stent placement. Participants must have a CT scan confirming upper tract stones, no urinary infection symptoms, and a negative urine culture before surgery.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive ureteral stents calibrated to their specific ureteral length or variable length stents
Follow-up
Participants are monitored for safety and effectiveness after treatment using the USSQ
What Are the Treatments Tested in This Trial?
Interventions
- Image-informed length ureteral stent
- Variable length ureteral stent
Trial Overview
The study compares two types of ureteral stents: one with a standard variable length and another where the length is customized to each person's anatomy using imaging. The goal is to see which type causes fewer discomforts after placement.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Find a Clinic Near You
Who Is Running the Clinical Trial?
Weill Medical College of Cornell University
Lead Sponsor
Citations
Long-term outcomes of Allium ureteral stent as a treatment ...
The median functional duration of the Allium stents was found to be 22 months (range:1–60 months), with an overall functioning rate at last ...
Ureteral stent complications
The obstruction of the ureteral stent, causing inefficient drainage, was encountered in 925 cases, while irritative bladder symptoms occurred in 16,326 cases.
The efficacy and safety of ureteral dilation and long-term ...
We demonstrated that ureteral dilation and placement of a single or multiple ureteral stents was effective and safe for patients with ureteral obstruction.
Comprehensive overview of ureteral stents based on clinical ...
The main objective of a ureteric stent is to allow passage of urine and reduce early or late complications related to obstruction in the urinary tract.
Stent Related Symptoms Defined by Ureteral ...
The purpose of this study is to determine whether ureteral stents whose lengths are calibrated to a participant's specific ureteral length based ...
Comparison of the efficacy and safety of metallic ureteral stent ...
This study aimed to evaluate and compare the clinical performance of metallic and polymer ureteral stents in patients with malignant ...
Image-Informed Length Ureteral Stents for ...
The purpose of this study is to determine whether ureteral stents whose lengths are calibrated to a participant's specific ureteral length based ...
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