Resistance Exercise for Type 1 Diabetes
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines how different types of weight lifting affect blood sugar levels in post-menopausal women with type 1 diabetes. Researchers compare two exercise routines: one with lighter weights and more repetitions (High repetition, HI) and another with heavier weights and fewer repetitions (Moderate repetition, MOD). The goal is to determine which routine more significantly impacts blood sugar during and after exercise. Women with type 1 diabetes who have not had a menstrual period for at least a year and can perform resistance exercises may be suitable for this study. Participants should reside near Edmonton, Alberta, to attend sessions at the University of Alberta. As an unphased trial, this study offers a unique opportunity to contribute to understanding how exercise can manage diabetes.
Will I have to stop taking my current medications?
The trial requires that participants do not take medications other than insulin that affect glucose metabolism, such as atypical antipsychotics or corticosteroids.
What prior data suggests that resistance exercise is safe for post-menopausal women with type 1 diabetes?
Research has shown that both high repetition and moderate repetition resistance exercises are generally safe for people with type 1 diabetes. Studies indicate that high-intensity interval exercise, similar to high repetition workouts, is safe for adults with diabetes and helps maintain normal blood sugar levels during and immediately after exercise.
For moderate repetition exercises, research supports that resistance training is safe and can improve heart health, benefiting individuals with and without heart-related conditions. Both exercise types safely lower blood sugar levels after exercising.
In summary, high repetition and moderate repetition exercises are well-tolerated and safe for individuals with type 1 diabetes, offering benefits without major safety concerns.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores how different resistance exercise protocols can benefit people with Type 1 Diabetes. Unlike traditional management options, which often focus on insulin therapy and dietary modifications, this study looks at how physical exercise, particularly high repetition, low resistance, and moderate repetition, moderate intensity workouts, can impact blood sugar control. The unique focus here is on understanding how different exercise intensities and repetitions might improve insulin sensitivity and overall metabolic health, potentially offering a non-pharmaceutical approach to managing the condition.
What evidence suggests that resistance exercise is effective for managing blood glucose levels in post-menopausal women with type 1 diabetes?
Research shows that strength training can help people with type 1 diabetes manage their blood sugar levels. In this trial, participants will undergo two separate interventions: a high repetition, low resistance protocol, and a moderate repetition, moderate intensity protocol. Studies indicate that many repetitions with lighter weights often cause a bigger drop in blood sugar during the workout. In contrast, a moderate number of repetitions with moderate weights may help keep blood sugar levels more stable immediately after exercising. Both types of strength training are linked to better long-term blood sugar control, which is crucial for managing type 1 diabetes. Thus, both high and moderate repetition exercises can be beneficial, each offering its own advantages.678910
Are You a Good Fit for This Trial?
This trial is for post-menopausal women with Type 1 Diabetes living near Edmonton, Alberta. They should have been diagnosed at least a year ago and not had a menstrual period in the last 12 months. Participants must be able to do resistance exercise but can't join if they have high blood pressure, cardiovascular disease history, are on certain medications, or have conditions affecting exercise ability.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-test Measures
Participants undergo pre-test measures including questions related to menopause, physical activity levels, medication, blood pressure, heart rate, anthropometric characteristics, and blood sample for HbA1c.
Testing Sessions
Participants perform resistance exercises in two sessions with different protocols, and blood samples are drawn at various times.
Follow-up
Participants are monitored for safety and effectiveness after exercise sessions, including CGM data collection and focus group participation.
What Are the Treatments Tested in This Trial?
Interventions
- High repetition (HI)
- Moderate repetition (MOD)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alberta
Lead Sponsor