200 Participants NeededMy employer runs this trial

Surgical Techniques for Trigger Finger

Recruiting at 1 trial location
NN
JS
Overseen ByJason Strezlow, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Washington University School of Medicine
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial compares two different surgical incisions to treat trigger finger, a condition where a finger becomes stuck or locked. The researchers aim to determine if the incision type affects recovery, pain, scar healing, and the speed of returning to daily activities. Participants will undergo surgery with either a straight incision along the finger or an incision across the palm crease, assigned randomly. This procedure is known as Open A1 Pulley Release. The trial seeks adults diagnosed with trigger finger who have not had surgery on the affected finger before. As an unphased trial, it offers participants the chance to contribute to understanding the best surgical approach for trigger finger.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that these surgical techniques are safe for treating trigger finger?

Research has shown that open A1 pulley release is generally safe for treating trigger finger, though minor issues can occur. In one study involving 527 fingers, 6.3% experienced minor problems such as wound issues, with 3.2% being very minor. Another study found that 94.4% of patients experienced complete symptom relief, with significant pain reduction. While open surgery is effective, needle-based methods often result in fewer complications and quicker recovery. Overall, open A1 pulley release is a well-tolerated option, but minor complications remain possible.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it's comparing two surgical techniques for treating trigger finger: longitudinal versus transverse incision in the open A1 pulley release. While the standard approach involves a longitudinal incision, this study explores whether a transverse incision might offer advantages such as reduced healing time or improved range of motion. By directly comparing these techniques, researchers aim to find out which method leads to better patient outcomes, potentially revolutionizing the way trigger finger surgeries are performed.

What evidence suggests that these surgical techniques are effective for trigger finger?

Research has shown that open A1 pulley release surgery effectively treats trigger finger, with success rates reaching 99% after three and twelve months. This surgery involves cutting a tight band in the finger to improve movement. In this trial, participants will receive one of two surgical techniques: a longitudinal incision along the finger's axis or a transverse incision in the distal palmar crease. Studies have found that while the surgery is effective, the incision type can influence recovery aspects such as pain and scarring. This trial aims to determine which incision type offers a better overall experience for patients.15678

Who Is on the Research Team?

JS

Jason Strelzow, MD

Principal Investigator

Associate Professor, Orthopaedic Surgery Division of Hand and Microsurgery, Washington University in St Louis

RC

Ryan Calfee, MD

Principal Investigator

Professor, Orthopaedic Surgery Division of Hand and Microsurgery Chief, Hand and Microsurgery Service Medical Director, Washington University and Barnes-Jewish Orthopedic Center

NN

Nisha N Kale, MD

Principal Investigator

Washington University in St. Louis Department of Orthopaedic Surgery

Are You a Good Fit for This Trial?

This trial is for adults (18 or older) diagnosed with trigger finger in any finger except the thumb, who have not had previous surgery on that finger and are scheduled for their first surgical release. Participants must agree to join the study.

Inclusion Criteria

Written informed consent obtained
I have trigger finger in one of my fingers, but not in my thumb.
I am 18 years old or older.

Exclusion Criteria

I am having a repeat or corrective surgery.
I have had surgery on the affected finger.
I do not agree to take part in this study.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Surgery

Participants undergo A1 pulley release surgery using either a longitudinal or transverse incision

1 day
1 visit (in-person)

Post-operative Monitoring

Participants report pain and have their scar assessed at follow-up visits

12 weeks
3 visits (in-person or virtual) at ~2, ~6, and ~12 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Open A1 Pulley Release

Trial Overview

The study compares two types of skin incisions used during trigger finger surgery: a straight cut along the finger (longitudinal) versus a cut across the palm crease (transverse). Patients are randomly assigned to one type and followed up after surgery.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Transverse IncisionExperimental Treatment1 Intervention
Group II: Longitudinal IncisionExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Washington University School of Medicine

Lead Sponsor

Trials
2,027
Recruited
2,353,000+

University of Chicago

Collaborator

Trials
1,086
Recruited
844,000+

Citations

A Two-Year Retrospective Comparison of Clinical Outcomes ...

Open surgery has been performed for many years and is 97% effective. However, it can cause surgical complications, such as pain after the ...

Comparative effectiveness of open versus percutaneous ...

The relative safety and effectiveness of percutaneous versus open A1 pulley release for trigger finger remain unclear.

Comparison of Two Surgical Techniques for the Treatment ...

The primary hypothesis is that A1 pulley resection will lead to fewer trigger finger recurrences after one year compared with longitudinal opening of the A1 ...

Comparative results of percutaneous and open surgery ... - PMC

Fifty percent of patients in the percutaneous release group experienced pain relief within two days, compared to seven days in the open release ...

Trigger Finger Release: A Technique for Ensuring Safe and...

Incomplete release of the A1 pulley risks relapse of triggering, whereas release of the A2 pulley places patients at risk for bowstringing.

A Two-Year Retrospective Comparison of Clinical ...

Percutaneous trigger finger release has been shown to produce superior outcomes compared to open surgery and is also a safer procedure, as ...

Ultrasound-Guided Percutaneous Versus Open A1 Pulley ...

Reported success rates for ultrasound-guided percutaneous release range from 90% to 100% [7,8]. In this context, we aimed to conduct a prospective, randomized ...

Trigger Finger Release: A Technique for Ensuring Safe and ...

Incomplete release of the A1 pulley risks relapse of triggering, whereas release of the A2 pulley places patients at risk for bowstringing.