Knee Positioning for Total Knee Replacement

BS
Overseen ByBrocha Stern
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Icahn School of Medicine at Mount Sinai
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines the optimal knee position after total knee replacement surgery. It will compare two groups: one with knees in a slightly bent position (knee flexion) and another with knees kept straight, the usual practice. The goal is to determine which position better aids knee movement and pain relief. Suitable candidates for this trial include those scheduled for knee replacement due to osteoarthritis, who speak English or Spanish, and who do not have chronic pain or bleeding issues. As an unphased trial, this study provides a unique opportunity to enhance post-surgery outcomes for future patients.

What prior data suggests that this knee positioning method is safe?

Studies have shown that bending the knee after surgery is generally safe and well-tolerated. One study found that patients using devices to assist knee bending after knee replacement surgery experienced good results, with no major side effects or complications. Another study found that patients of varying body sizes, whether overweight or not, had similar recovery outcomes when knee bending was included in their rehabilitation. This suggests that knee bending can be a safe option for many patients, regardless of body size. Overall, research supports that knee bending treatments after surgery are generally safe for patients.12345

Why are researchers excited about this trial?

Researchers are excited about the knee flexion intervention for total knee replacement because it explores a new approach to post-surgery care. Unlike the standard practice where the knee is kept in extension, this method involves positioning the knee in flexion early after surgery. This could potentially enhance recovery by improving range of motion and reducing stiffness faster than usual care. By investigating the effects of knee flexion positioning, researchers hope to find a more effective way to support patients in their rehabilitation process.

What evidence suggests that knee flexion is effective for knee replacement recovery?

This trial will compare knee flexion with usual care after total knee replacement surgery. Studies have shown that bending the knee after surgery can aid recovery. Research indicates that patients who keep their knees slightly bent often experience better movement and less stiffness than those who keep their knees straight. Some findings also suggest that this position might help reduce pain during recovery. While no definite recommendation exists yet, these early findings highlight the potential benefits of knee bending to improve recovery after surgery. Participants in this trial will either receive the knee flexion intervention or usual care, where no specific attention will focus on knee positioning.678910

Who Is on the Research Team?

BH

Brett Hayden, MD

Principal Investigator

Icahn School of Medicine at Mount Sinai

Are You a Good Fit for This Trial?

This trial is for adults who have just had a total knee replacement surgery. People with certain medical conditions or complications may not be able to join, but specific exclusions are not listed.

Inclusion Criteria

I am 18 years old or older.
My knee replacement is due to diagnosed knee osteoarthritis.
Provision of signed and dated informed consent form
See 3 more

Exclusion Criteria

I am scheduled to have more than one procedure at the same time.
I have trouble understanding or cannot give consent on my own.
I am getting a knee replacement because of trauma, bone death, tumor, or Charcot joint.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Immediate Postoperative Care

Participants receive knee positioning intervention immediately after surgery

2-4 hours
In-hospital care

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months
Routine care visits at 2.5 weeks, 6 weeks, 3 months, 6 months, and 12 months

What Are the Treatments Tested in This Trial?

Interventions

  • Knee Flexion

Trial Overview

The study compares two ways of positioning the knee right after knee replacement: keeping it slightly bent versus keeping it straight (standard care). Researchers want to see which position helps more with movement and pain.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Knee FlexionExperimental Treatment1 Intervention
Group II: Usual CareActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Icahn School of Medicine at Mount Sinai

Lead Sponsor

Trials
933
Recruited
579,000+

Citations

1.

totalenergies.com

totalenergies.com/

TotalEnergies - integrated multi-energy company ...

TotalEnergies is a global integrated energy company that produces and markets energies: oil and biofuels, natural gas and green gases, renewables and ...

Total (group)

Total is an American R&B girl group and one of the signature acts of the Bad Boy Records imprint during the mid-1990s. The group consists of founding ...

Total Wine & More | Liquor Store and Alcohol Delivery

Over 8000 wines, 3000 spirits & 2500 beers with the best prices, selection and service at Total Wine & More. Shop online for delivery, curbside or in-store ...

Total

Listen to Total on Spotify. Artist · 916.3K monthly listeners.

Total Taxable Resources | U.S. Department of the Treasury

Treasury estimates of total taxable resources by state for federal grant allocation purposes.

The Role of Surgical Closure Position in Total Knee Arthroplasty

The primary outcomes were the knee flexion degrees and the American Knee Society Score values at preoperative and postoperative 6 weeks, 3, and 6 months.

Reference chart for knee flexion following total ...

Our study aimed to develop and validate a reference chart for monitoring recovery of knee flexion following TKA surgery.

8.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/33111265/

Long-Term Postoperative Total Knee Arthroplasty Flexion ...

In conclusion, long-term postoperative ROM outcomes were similar between patients who were nonobese and patients who were obese.

Reference chart for knee flexion following total ...

The goal of this study was to develop and validate a reference chart with clinically collected data, to inform monitoring of knee flexion active range of motion.

Long-Term Outcomes of High-Flexion Design Total Knee ...

studies using VEGA Knee System have reported good clinical outcomes and no evidence of 12 cases), were unable to contact (phone or mail; 10 cases), and had ...