Ultrasound Imaging for Oral Cancer

(SURGIO Trial)

This trial aims to enhance the effectiveness of oral cancer surgeries by incorporating ultrasound technology during the procedure. The goal is to enable surgeons to remove tumors with greater precision, potentially reducing the need for follow-up treatments, such as additional surgeries or radiation. Participants will be divided into two groups: one will undergo the usual surgery, while the other will have surgery with ultrasound guidance performed by the surgeon. The trial seeks individuals diagnosed with specific types of oral cancer who are scheduled for surgery. As an unphased trial, it offers a unique opportunity to contribute to advancements in surgical precision and potentially improve outcomes for future patients.

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Research has shown that ultrasound use during surgeries, when performed by surgeons, is very safe. One study found that this method helped locate tumors more accurately without harming patients. Another study confirmed its safety and suggested it might help surgeons remove tumors more effectively.

Ultrasound has primarily been used before surgery to measure the size of oral tumors and has proven accurate. By providing real-time images to guide surgery, it adds no extra risk. The technology is non-invasive, using sound waves to create pictures without entering the body.

Researchers are excited about using surgeon-performed ultrasound for oral cancer because it offers real-time imaging to guide the surgery. Unlike standard surgical methods that rely on visual inspection and palpation, this technique uses ultrasound to provide a clear view of the surgical margins during the procedure. This could potentially lead to more precise removal of the tumor, minimizing the chances of leaving cancerous tissue behind. The ability to visualize the resection plane as a hyperechoic border in real-time is a game-changer, as it may improve surgical outcomes and reduce the need for additional surgeries.

This trial will compare standard surgical procedures with the use of surgeon-performed ultrasound during oral cancer surgeries. Research has shown that ultrasound during these surgeries can improve tumor removal accuracy. Studies have found that ultrasound allows doctors to see and measure tumors more clearly during surgery. This real-time imaging can lead to cleaner cancer removal, leaving less behind. Achieving clear margins can reduce the need for additional treatments like radiation. This method might also lower the risk of cancer recurrence and enhance the overall quality of life for patients.²³⁵⁶⁷