Mepilex Dressing for Surgical Site Infection
(MEPIDEL Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this clinical trial is to learn whether a silver-containing foam dressing (Mepilex Border Post-Op Ag) works as well as the standard dressing in preventing surgical site infection after cesarean delivery. The main questions it aims to answer are:
Is the rate of surgical site infection with Mepilex Border Post-Op Ag no worse than with the standard dressing?
How do the two dressings compare for other wound problems, wound-related hospital or clinic visits, and patient satisfaction?
Researchers will compare participants who receive Mepilex Border Post-Op Ag with participants who receive the standard dressing.
Participants will:
1. Have their cesarean delivery as planned by their care team
2. Be randomly assigned to one of the two dressings, which is placed over the incision at the end of surgery
3. Complete a short questionnaire about their dressing
4. Receive a follow-up phone call about 30 to 40 days after delivery (POD 30-40) to check on their wound
Who Is on the Research Team?
Lilly Liu, MD, MPH
Principal Investigator
Montefiore Medical Center
Are You a Good Fit for This Trial?
This trial is for people having a planned cesarean delivery. Participants must be able to have either type of wound dressing placed after surgery and complete follow-up checks.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Mepilex Border Post-Op Ag
- Standard Postoperative Dressing
Trial Overview
The study compares two types of dressings used after C-section: a silver-containing foam dressing (Mepilex Border Post-Op Ag) versus the standard postoperative dressing, assigned randomly. Researchers will look at infection rates, wound problems, and patient satisfaction.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants will receive a single Mepilex Border Post-Op Ag dressing applied over the cesarean incision immediately after skin closure in the operating room. The dressing is intended to remain in place until approximately postoperative day 7 (POD 7) unless earlier removal is clinically indicated or requested by the participant. If the dressing is removed early, it may be replaced at the treating physician's discretion.
Participants will receive the institution's standard postoperative cesarean dressing, applied over the incision immediately after skin closure in the operating room. The dressing is typically removed on POD 1 or POD 2 according to routine institutional practice.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Montefiore Medical Center
Lead Sponsor
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