Cognitive Prehabilitation for Postoperative Complications

LA
EH
Overseen ByEmily Hladkowicz, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Ottawa Hospital Research Institute
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The Advancing Cognition and Cognitive reserve before ELective surgery to Enhance cognitive Recovery And TrajEctories (ACCELERATE) Pilot Trial estimates whether our novel, coach-supported cognitive prehabilitation strategy will achieve adequate intervention adherence in the context of a feasible multicenter trial protocol.

Who Is on the Research Team?

LA

Leandra Amado, MD

Principal Investigator

The Ottawa Hospital

Are You a Good Fit for This Trial?

This trial is for people aged 60 or older who are considered moderately frail, can make their own medical decisions, and are scheduled for certain types of inpatient surgery at least four weeks away. It excludes those with vision problems, not fluent in English, or having heart or brain surgeries.

Inclusion Criteria

Clinical Frailty Scale (CFS) score >= 4
I am able to understand and agree to surgery on my own.
My surgery is scheduled at least 4 weeks from now.
See 2 more

Exclusion Criteria

Visual impairment
Lack of English fluency
I have had heart or brain surgery.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Cognitive Prehabilitation

Participants engage in a home-based, online, adaptive, multidomain cognitive prehabilitation program using Lumosity, enhanced by structured coaching

Minimum of 4 weeks pre-surgery

Surgery and Immediate Postoperative Assessment

Participants undergo surgery and are assessed for delirium at specified timepoints post-surgery

3 days
In-hospital assessments: 1 hour after emergence, twice daily on postop days 1, 2, and 3

Follow-up

Participants are monitored for safety and effectiveness after surgery

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Cognitive Prehabilitation

Trial Overview

The study is testing a new program where participants do coach-supported mental exercises before surgery to see if it helps them recover better mentally after the operation. The focus is on whether patients will stick with this program.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Intervention (cognitive prehabilitation)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Ottawa Hospital Research Institute

Lead Sponsor

Trials
585
Recruited
3,283,000+

Canadian Anesthesiologists' Society

Collaborator

Trials
19
Recruited
3,000+

University of Ottawa Anesthesiology and Pain Medicine

Collaborator