Home-Based Vision Rehabilitation for Visual Field Loss

(BRIGHT Trial)

This trial tests whether home-based visual training can improve sight in people with visual field loss. It explores two types of online visual exercises to determine which is more effective: one uses complex images (high-level perceptual learning-based training), while the other uses simple ones (low-level perceptual learning-based training). Researchers aim to understand how the brain adapts during this training. The trial seeks participants who have experienced vision loss due to brain injury or stroke and have been stable for at least three months. As an unphased study, this trial offers a unique opportunity to contribute to groundbreaking research that could enhance visual rehabilitation methods.

Research has shown that perceptual learning, a method to improve vision, is generally well-tolerated. In one study on advanced perceptual learning, participants reported no negative effects and demonstrated better visual perception and faster reading. Another review of computer-based vision training found similar results, with no major side effects.

For basic perceptual learning, a study examined eye movement training for vision loss and found it effective and safe. However, some results suggest that the benefits can vary.

Researchers are excited about the home-based vision rehabilitation program because it offers a unique, accessible approach to improving visual field loss through perceptual learning. Unlike traditional treatments, which often involve in-office therapy or surgery, this method leverages online training that users can do from the comfort of their homes. The trial investigates two distinct approaches: high-level and low-level visual stimuli training, providing insights into which method might be more effective. This at-home, online delivery method could revolutionize how vision rehabilitation is accessed, making it more convenient and potentially more engaging for patients.

This trial will compare two types of perceptual learning-based training for vision rehabilitation. Studies have shown that perceptual learning can significantly enhance vision in individuals with vision loss. Participants in one arm of this trial will undergo high-level perceptual learning, which involves complex visual tasks and may help restore vision in specific areas. This could lead to improvements in how they perceive and interpret their surroundings. Participants in the other arm will engage in low-level perceptual learning, which involves simpler visual tasks and has been found to enhance basic vision skills like reading and recognizing objects. Although the effectiveness of these methods varies, many patients report lasting improvements in their vision. Both types of training offer promising ways to help individuals with vision loss see better.¹²³⁶⁷