24 Participants Needed

Brain Training for Spinal Cord Injury

(SCI-IQ Trial)

Recruiting at 2 trial locations
EW
Overseen ByErica Weber
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Kessler Foundation

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether a cognitive training program can improve the thinking speed of individuals with recent spinal cord injuries. Participants will engage in game-like computer exercises three times a week for 12 weeks. Some will perform these specific activities, while others will complete placebo tasks for comparison. This trial suits adults who experienced a traumatic spinal cord injury within the last six months and do not have other major neurological conditions. As an unphased trial, it offers participants the chance to contribute to groundbreaking research that could enhance cognitive recovery strategies.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that this cognitive training program is safe for individuals with spinal cord injury?

Research has shown that game-like computer activities are generally safe for people with spinal cord injuries. Studies have found that similar computer-based exercises, such as virtual reality rehab, are well-tolerated and can enhance physical abilities without causing harm. For instance, one study found that virtual reality training improved walking and balance in people with spinal cord injuries, with no serious side effects reported.

Although this specific cognitive training program is new, the use of computer games for rehab has a history of safety. The activities involve repeating specific tasks, which are typically low-risk. Studies of these activities have reported no serious problems, suggesting they are safe to try.12345

Why are researchers excited about this trial?

Researchers are excited about this brain training method for spinal cord injury because it offers a novel, non-invasive approach that aims to improve cognitive function through game-like computerized activities. Unlike traditional treatments that focus primarily on physical rehabilitation, this method leverages cognitive training to potentially enhance neural pathways and brain plasticity. By engaging patients in regular, structured cognitive exercises, it could offer an innovative way to support overall recovery and improve quality of life, addressing an aspect often overlooked by standard physical therapies.

What evidence suggests that this cognitive training program is effective for improving processing speed in spinal cord injury?

Research has shown that game-like computer activities, which participants in this trial may receive, can help improve thinking skills. Studies have found that these digital games can enhance cognitive speed in people with spinal cord injuries. For example, one study on brain injuries found that serious games for mental exercises can be beneficial. Another study demonstrated that digital games could improve thinking skills and overall well-being. These findings suggest that the computer activities in this trial might help people with spinal cord injuries think more quickly.46789

Who Is on the Research Team?

EW

Erica Weber, PhD

Principal Investigator

Kessler Foundation

Are You a Good Fit for This Trial?

This trial is for individuals aged 18-59 who have recently experienced a traumatic spinal cord injury, approximately within the last 6 months. It's designed to help those facing cognitive impairments due to their injury.

Inclusion Criteria

My spinal cord injury happened about 6 months ago.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in pre-specified computer tasks using an Internet-based cognitive training portal, 3 times per week for 60 minutes each session

12 weeks
36 sessions (virtual)

Immediate Post-Treatment Assessment

Assessment of cognitive processing speed using SDMT, UFOV, and LPC tasks

1 week
1 visit (in-person or virtual)

Follow-up

Participants are monitored for long-term effects on cognitive processing speed and quality of life

12 weeks
1 visit (in-person or virtual)

What Are the Treatments Tested in This Trial?

Interventions

  • game-like computerized activities
  • Placebo
Trial Overview The study is testing if game-like computerized activities can speed up how fast patients with acute spinal cord injuries process information. Some participants will use these activities while others will receive a placebo as a comparison.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Placebo Group
Group I: ExperimentalExperimental Treatment1 Intervention
Group II: Placebo ControlPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Kessler Foundation

Lead Sponsor

Trials
190
Recruited
11,300+

University of Washington

Collaborator

Trials
1,858
Recruited
2,023,000+

Craig Hospital

Collaborator

Trials
45
Recruited
8,400+

Published Research Related to This Trial

Combining traditional trunk control training with iPad game apps led to significant improvements in trunk control for patients with low thoracic spinal cord injuries, as evidenced by increased scores on both game performance and the Trunk Recovery Scale.
Patients reported positive experiences with the rehabilitation approach, indicating that the use of technology in therapy can enhance motivation and engagement in recovery.
Tablet Technology for Rehabilitation after Spinal Cord Injury: a Proof-of-Concept.Fizzotti, G., Rognoni, C., Imarisio, A., et al.[2016]
In a study of 42 spinal cord injury patients, those who underwent semi-immersive virtual reality cognitive training showed significant improvements in global cognitive functioning, mood, and quality of life compared to those receiving traditional therapy.
The results suggest that integrating cognitive exercises with movement and feedback in virtual reality can enhance both cognitive and motor recovery in patients with spinal cord injuries.
Do Individuals with Spinal Cord Injury Benefit from Semi-Immersive Virtual Reality Cognitive Training? Preliminary Results from an Exploratory Study on an Underestimated Problem.Maggio, MG., Bonanno, M., Manuli, A., et al.[2023]
A 60-year-old man with incomplete cervical spinal cord injury showed significant improvements in cognitive function, anxiety, and motor performance after a combined rehabilitation approach that included virtual reality training.
The use of virtual reality rehabilitation systems (VRRS) demonstrated effectiveness in enhancing recovery for patients with both motor and cognitive deficits, suggesting it could be a valuable tool in neurological rehabilitation.
A novel use of virtual reality in the treatment of cognitive and motor deficit in spinal cord injury: A case report.Maresca, G., Maggio, MG., Buda, A., et al.[2022]

Citations

Rehabilitative game-based system for enhancing physical ...The aim of the game was to improve the motor skills of a traumatic brain injury patient and stroke by increasing the strength of the muscles.
Computer Game-based Exercise Program Targeting ...Based on the above considerations a low cost computer game based rehabilitation platform was developed that combines fine manipulation and gross movement ...
Brain Training for Spinal Cord Injury (SCI-IQ Trial)Trial Overview The study is testing if game-like computerized activities can speed up how fast patients with acute spinal cord injuries process information.
Development of a serious game-based cognitive ...This study aims to develop a serious game-based cognitive rehabilitation system tailored for patients with brain injury.
Digital Gaming for Improving the Functioning of People ...Objective: The aim of this study was to determine whether rehabilitative digital gaming facilitates cognitive functioning and general well-being ...
Effects of virtual reality rehabilitation after spinal cord injuryVR has shown promise in enhancing walking ability and balance function in individuals with SCI. However, the existing evidence for VR interventions in SCI ...
Computer Game-based Exercise Program Targeting ...It's no sleight of hand our gaming system provides a basis for repetitive, task-specific therapy focused on manual dexterity; object handling and manipulation ...
Pilot Study of Home-Based Virtual Reality Fitness Training ...This study investigates the effectiveness of home-based virtual reality fitness training (VRFT) as a convenient and accessible rehabilitation ...
(PDF) Computer Game-Based Telerehabilitation Platform ...A Computer game-assisted Tele-Rehabilitation Platform (GTP) has been developed to address this need. With the novel application of a miniature ...
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security