52 Participants NeededMy employer runs this trial

Suturing Techniques for Skin Graft Scars

Recruiting at 1 trial location
ML
Overseen ByMarcus L Elias, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Northwell Health
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores the best method for stitching skin grafts after dermatologic surgery to determine which technique results in better-looking scars. Participants will have one half of their scar treated with the running epidermal suture (Running Suturing Technique) and the other half with the simple interrupted suture (Simple Interrupted Suturing Technique) to compare results. Individuals who have undergone a full-thickness skin graft to close a wound from skin surgery may be suitable for this study. As an unphased trial, it offers participants the chance to contribute to valuable research that could enhance future surgical outcomes.

What prior data suggests that these suturing techniques are safe for skin graft scars?

Research has shown that both running and simple interrupted stitching methods are generally safe for skin grafts. Studies have found that continuous (running) stitches reduce the risk of the wound reopening compared to interrupted stitches. Infection rates do not significantly differ between these two methods.

Additionally, reviews of full-thickness skin graft techniques reveal no noticeable differences in important outcomes, such as graft adherence or complications like blood pooling under the skin or infection.

Overall, both stitching methods are well-tolerated by patients, offering similar safety levels regarding pain, scarring, and patient satisfaction.12345

Why are researchers excited about this trial?

Researchers are excited about this trial because it compares two different suturing techniques—Running Suturing Technique and Simple Interrupted Suturing Technique—for skin graft scars. These techniques might affect how well the scar heals and how it looks afterward. By understanding which method leads to better cosmetic outcomes, the trial aims to improve patient satisfaction and healing times. This could potentially enhance the current standard of care for managing skin graft scars.

What evidence suggests that these suturing techniques are effective for skin graft scars?

This trial will compare the effectiveness of two suturing techniques for skin graft scars: the Running Suturing Technique and the Simple Interrupted Suturing Technique. Research has shown that both methods are effective for skin grafts. Studies have found that the appearance of a scar can depend on the stitching method used. The Simple Interrupted method is commonly used and effectively closes wounds, with stitch marks typically fading within 90 days. The Running method is also suitable, and some research suggests it might be equally effective in terms of scar appearance. Both methods are acceptable, and the choice may depend on the specific situation and the surgeon's preference. Participants in this trial will be assigned to one of the two techniques to evaluate their effectiveness.678910

Who Is on the Research Team?

VR

Victoria R Sharon, MD

Principal Investigator

Northwell Dermatology

Are You a Good Fit for This Trial?

This trial is for patients who are getting a full-thickness skin graft as part of dermatologic surgery, like Mohs micrographic surgery or excision. The study will compare the cosmetic outcomes of two different suturing techniques on their scars.

Inclusion Criteria

Planned enrollment based on a priori sample size calculation is 52 patients
I am having a skin graft to close a wound after skin surgery.
I can come back for follow-up visits.
See 2 more

Exclusion Criteria

I am not having a surgery that involves moving a piece of skin from one part of my body to another.
I cannot or do not want to come back for follow-up visits.
My skin graft is too small for 3 stitches on one side.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Surgery and Suturing

Participants undergo dermatologic surgery with full-thickness skin graft placement using either simple interrupted or running epidermal sutures

1 day
1 visit (in-person)

Follow-up

Participants are monitored for cosmetic outcomes and complications, including scar assessment using POSAS 2.0

3 months
1 visit (in-person)

Extended Follow-up

Participants are monitored for long-term complications and overall scar quality

1 year

What Are the Treatments Tested in This Trial?

Interventions

  • Running Suturing Technique
  • Simple Interrupted Suturing Technique

Trial Overview

The trial is testing if running epidermal sutures give similar or better cosmetic results compared to simple interrupted sutures in skin grafts. Each participant's scar will be split; one half gets running sutures and the other half gets interrupted ones, with results checked after 3 months.

How Is the Trial Designed?

2

Treatment groups

Active Control

Group I: Half A of the FTSGActive Control2 Interventions
Group II: Half B of the FTSGActive Control2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Northwell Health

Lead Sponsor

Trials
481
Recruited
470,000+

Citations

Effectiveness

Effectiveness or effectivity [1] is the capability of producing a desired result or the ability to produce desired output.

Evaluation Criteria

The OECD has defined six evaluation criteria – relevance, coherence, effectiveness, efficiency, impact and sustainability – and two principles for their use.

3.

pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/24162032/

Increased effectiveness of early therapy with anti-tumor ...

early monotherapy with anti-TNFα produced better overall clinical and growth outcomes at 1 year than early monotherapy with an immunomodulator.

4.

homvee.acf.gov

homvee.acf.gov/home

What is Home Visiting Evidence of Effectiveness? | Home ...

This video explains how HomVEE reviews research, rates model effectiveness, and determines which models meet criteria for evidence of effectiveness.

Institutional Effectiveness

The Institutional Effectiveness division draws upon the expertise and innovation within the California Community Colleges to advance promising practices.

A review of sutures and suturing techniques.

Proper suturing technique is essential for obtaining good cosmetic results and avoiding scarring and poor wound healing. The ideal suture is strong, ...

Full-thickness Skin Graft Fixation Techniques: A Review ...

No significant differences were found between fixation methods for graft take, haematoma rate, and infection rate. No studies have found a significant ...

Comparing Continuous and Interrupted Sutures

Continuous sutures also had a lower risk of dehiscence than interrupted sutures. There was no significant difference in infection rates between the two suture ...

(PDF) Best Skin Suture: Interrupted or Continuous?

Conclusion: Results did not show the difference between two sutures in term of pain and scar width, although the satisfaction of patients with ...

Study Details | NCT00282633 | Wound Closure Techniques

A prospective, observer blinded, randomized, and controlled trial comparing Dermabond closure technique to suture closure of skin. Study ...