Therapeutic Diet and Lifestyle for Multiple Sclerosis

This trial aims to determine if a therapeutic lifestyle, including diet, stress reduction, and exercise, can match the effectiveness of traditional drug treatments for people with multiple sclerosis (MS), specifically those with clinically isolated syndrome (CIS) or relapsing-remitting multiple sclerosis (RRMS). Participants will be divided into two groups: one receiving standard care from their neurologist and the other following the therapeutic lifestyle program. The study will examine changes in symptoms, function, and quality of life. Individuals diagnosed with CIS or RRMS within the last year and residing in the lower 48 states of the U.S. may be eligible.

As an unphased trial, this study provides a unique opportunity to explore alternative treatments that could enhance quality of life.

The trial does not specify if you need to stop taking your current medications, but it does exclude those taking insulin or Coumadin®. It's best to discuss your specific medications with the study team.

Research has shown that lifestyle changes, such as eating a healthy diet and exercising, can significantly help manage multiple sclerosis (MS) symptoms. Studies have found that these changes can reduce inflammation and improve the quality of life for people with MS. For instance, one study found that the Mediterranean diet, which includes many fruits, vegetables, and healthy fats, is not only safe but also effective in treating MS.

Another study revealed that half of the people with MS change their diets to help manage their symptoms. These lifestyle changes are usually well-tolerated, meaning most people do not experience negative side effects. Instead, they often feel more energetic and generally better.

Researchers are excited about the therapeutic diet and lifestyle approach for multiple sclerosis (MS) because it offers a non-pharmacological alternative to traditional treatments like disease-modifying therapies (DMTs), which often involve injectable or oral medications. Unlike these standard options, which primarily target the immune system to slow disease progression, the therapeutic lifestyle focuses on reducing MS-related fatigue and enhancing quality of life through diet and lifestyle changes. This method emphasizes patient empowerment by equipping individuals with practical strategies to manage their condition actively. By exploring how lifestyle adjustments can impact MS, researchers hope to uncover new avenues for improving patient well-being without relying solely on medication.

Research has shown that changes in diet and lifestyle can reduce tiredness and improve the quality of life for people with multiple sclerosis (MS). In this trial, participants in the Therapeutic Lifestyle arm will receive training through seminar videos on using a therapeutic diet and lifestyle to reduce MS-related fatigue and enhance quality of life. One study found that MS patients felt less tired and experienced a better quality of life after changing their diet. Up to 50% of people with MS have reported that dietary changes help manage their symptoms. Early studies also suggest that diets low in sugar and calories can benefit people with MS. These findings highlight the potential benefits of focusing on diet and lifestyle to ease MS symptoms.¹²⁵⁶⁷