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Executive Function and CBT for Schizophrenia

(ECBSST R33 Trial)

Not yet recruiting at 1 trial location
JH
EG
Overseen ByEric Granholm, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of California, San Diego
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This randomized controlled clinical trial will test a blended intervention that combines Executive Function Training with Cognitive-Behavioral Skills Training (E-CBSST). E-CBSST will be delivered to adults with late-life schizophrenia to determine if it increases Cognitive Behavioral Social Skills Training skills learning more than a supportive contact control condition and leads to improved functioning.

Who Is on the Research Team?

EG

Eric Granholm, PhD

Principal Investigator

University of California, San Diego

TR

Tarek Rajji, MD

Principal Investigator

UT Southwestern

Are You a Good Fit for This Trial?

This trial is for adults with schizophrenia or schizoaffective disorder, especially those in later life. Participants should be able to take part in group sessions and not have other conditions that would prevent them from completing the study.

Inclusion Criteria

Voluntary informed consent to participate
I have been diagnosed with schizophrenia or schizoaffective disorder.
Be clinically stable as defined by no psychiatric hospital admission within three months prior to assessment
See 5 more

Exclusion Criteria

I have a condition that affects my ability to participate in cognitive training.
Meets diagnostic criteria for bipolar disorder, current major depressive episode, or substance abuse or dependence within six months prior to baseline assessment except caffeine or nicotine
I have had electroconvulsive therapy in the past six months.

What Are the Treatments Tested in This Trial?

Interventions

  • E-CBSST
  • E-SC

Trial Overview

The study compares a new program (E-CBSST) that combines executive function training with cognitive-behavioral social skills training against a supportive contact control group. Participants are randomly assigned to one of these groups.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: E-CBSSTExperimental Treatment1 Intervention
Group II: E-SCActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Diego

Lead Sponsor

Trials
1,215
Recruited
1,593,000+

University of Texas Southwestern Medical Center

Collaborator

Trials
1,102
Recruited
1,077,000+

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