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Sugar Beverages for Blood Sugar Response

Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Purdue University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This randomized, double-blind, crossover study will evaluate postprandial blood glucose and glucagon-like peptide-1 (GLP-1) responses to different sugar-containing beverages in healthy adults. The study will also evaluate whether the addition of epigallocatechin gallate (EGCG), a compound found in green tea, modifies glucose and GLP-1 responses. Participants will complete four study visits and consume a different study beverage at each visit. Blood samples will be collected to measure glucose, GLP-1, and insulin, and participants will complete questionnaires assessing satiety and sensory perception.

Who Is on the Research Team?

BH

Bruce Hamaker

Principal Investigator

Purdue University

Are You a Good Fit for This Trial?

This trial is for healthy adults. People with health conditions or on medications that affect blood sugar, or who have allergies to the study ingredients, cannot participate.

Inclusion Criteria

Fasting blood glucose ≤100 mg/dL (assessed in the screening visit by finger prick)
Body mass index (BMI) between 18.5 and 24.9 kg/m² (self-report in prescreening questionnaire and confirmed in screening with height and weight measurements)
Availability to provide written informed consent
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Exclusion Criteria

Acute illness at the time of a study visit or inability to comply with study procedures such as fasting or repeated sampling
Pregnant or lactating individuals
Known allergy or intolerance to study beverage components, including caffeine or EGCG
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What Are the Treatments Tested in This Trial?

Trial Overview

The study tests how different sugary drinks—with and without EGCG (a green tea compound)—affect blood sugar and hormone levels after eating. Each participant tries all four drinks in random order over separate visits.

How Is the Trial Designed?

4

Treatment groups

Experimental Treatment

Group I: Sucrose beverageExperimental Treatment1 Intervention
Group II: Sucrose + EGCG beverageExperimental Treatment1 Intervention
Group III: Glucose + Fructose beverageExperimental Treatment1 Intervention
Group IV: Glucose + Fructose +EGCG beverageExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Purdue University

Lead Sponsor

Trials
239
Recruited
72,200+

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