20 Participants NeededMy employer runs this trial

Breath Analyzer for Viral Respiratory Infection

GF
Overseen ByGwenyth Fischer
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: University of Minnesota
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine if the MBP® Breath Analyzer can detect differences in breath patterns between children with respiratory illnesses and those without. Children aged 7 to 17 who have symptoms like fever, cough, or a runny nose might be suitable candidates. Those without these symptoms, visiting the emergency room for minor injuries, can also participate. Participants will breathe normally into the device for about a minute. The study will assess the device's effectiveness in identifying respiratory infections through breath analysis. As an unphased trial, this study provides a unique opportunity to contribute to innovative research that may enhance diagnostic tools for respiratory illnesses.

What prior data suggests that the MBP® Breath Analyzer is safe for pediatric use?

Research on the MBP® Breath Analyzer hasn't yet provided specific safety details. However, this device is non-invasive, meaning it doesn't enter the body. Participants simply breathe into it for about a minute. The trial is labeled "Not Applicable" for phases, indicating a focus on testing the device's effectiveness rather than its safety.

Similar studies have shown that breath analysis devices are generally easy to use and don't cause serious side effects, as they don't involve medication or invasive procedures. Therefore, the MBP® Breath Analyzer is likely safe to use, even without specific data from this study. Consulting a healthcare provider for personal advice is always recommended.12345

Why are researchers excited about this trial?

Researchers are excited about the MBP® Breath Analyzer trial because it offers a completely new way to detect viral respiratory infections. Unlike traditional methods, which rely on swabs or blood tests, this breath analyzer is non-invasive and quick, providing results by simply analyzing a breath sample. This could make diagnosing respiratory illnesses faster and more comfortable, especially for kids who might find other tests scary or uncomfortable. By comparing breath samples from children with symptoms to those without, researchers hope to refine this tool for easy and rapid diagnosis in emergency settings.

What evidence suggests that the MBP® Breath Analyzer is effective for detecting viral respiratory infections?

Research has shown that analyzing breath can help identify respiratory infections by detecting certain chemicals. In this trial, the MBP® Breath Analyzer will detect these chemicals, which may change during an infection. Participants in the Acute Respiratory Illness Group will provide breath samples to test the device's effectiveness in identifying infections. Meanwhile, the Healthy Control Group will provide breath samples to help differentiate between healthy individuals and those with respiratory illnesses. Although specific data on this device's effectiveness is not yet available, similar technologies have shown promise in distinguishing healthy individuals from those with respiratory illnesses. This suggests that the breath analyzer might spot infections by examining unique chemical patterns in breath samples. Early results from similar studies support the idea that breath analysis can be a useful tool for detecting respiratory issues.678910

Who Is on the Research Team?

GF

Gwenyth Fischer

Principal Investigator

University of Minnesota

Are You a Good Fit for This Trial?

This trial is for children ages 7 to 17 who visit the emergency department. It includes those with symptoms of a respiratory infection and healthy kids there for minor injuries, but not those with other health issues that could affect results.

Inclusion Criteria

I can comfortably breathe into a device for 1 minute.
I do not have symptoms of a recent respiratory illness.
I am between 7 and 17 years old.
See 5 more

Exclusion Criteria

Unable to comfortably breathe normally into the MBP® Breath Analyzer for 1 minute
Patient with research opt-out status in the medical record
Has eaten in the 30 minutes prior to use
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1 week

Study Visit

Participants provide a breath sample using the MBP® Breath Analyzer

45 minutes
1 visit (in-person)

Follow-up

Participants are monitored for differences in VOC signal profiles

72 hours

What Are the Treatments Tested in This Trial?

Interventions

  • MBP® Breath Analyzer

Trial Overview

The study tests if the MBP® Breath Analyzer can detect differences in breath chemicals between sick and healthy children by having them breathe into the device for about one minute.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Healthy Control GroupExperimental Treatment1 Intervention
Group II: Acute Respiratory Illness GroupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Minnesota

Lead Sponsor

Trials
1,459
Recruited
1,623,000+

Citations

ATS Breathe Easy: Tackling Bacterial Pneumonia in ICU Patients

These infections carry a high risk of mortality and are frequently caused by multidrug-resistant bacteria like MRSA. On this episode of the ATS ...

http://doi.org/10.1055/s-0036-1584803

No information is available for this page.

https://respiratory-research.biomedcentral.com/art...

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https://www.altmetric.com/details/115935033

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ACUTE Definition & Meaning

The meaning of ACUTE is characterized by sharpness or severity of sudden onset. acute illness see also acute disease ・ respiratory distress ...

Infection

Antivirals for viral infections. an estimated 18.6% of global deaths in 2017. As bacterial and viral infections can both cause the same kinds of symptoms,

Infection | Springer Nature Link

Infection is a peer-reviewed journal dedicated to presenting and discussing clinically relevant information on infectious diseases globally.

Acute - Medical Encyclopedia

Acute means sudden. Acute symptoms appear, change, or worsen rapidly. It is the opposite of chronic.

10.

infection.github.io

infection.github.io/

Infection

Infection mutates your source code and tells you which changes your test suite fails to catch. Infection changes the code under test and reports the mutations ...