Indoor Overheating for COPD
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines how older adults with chronic obstructive pulmonary disease (COPD) respond to warm indoor temperatures. Participants will spend one day in a room set at the recommended 26 °C and another day in a warmer room at 36 °C. Researchers will monitor body temperature, heart rate, lung function, and more to understand how heat affects those with COPD. The goal is to improve guidelines for maintaining safe indoor temperatures during hot weather. Individuals with COPD for over 5 years who are not experiencing recent flare-ups or infections might be suitable for this trial. As an unphased trial, this study allows participants to contribute to important research that could enhance safety guidelines for others with COPD.
What prior data suggests that this protocol is safe for individuals with COPD?
Research has shown that very warm indoor spaces can worsen symptoms for people with chronic obstructive pulmonary disease (COPD). Specifically, studies have found that high indoor temperatures can intensify COPD symptoms, particularly when the air is polluted. Consequently, hot and stuffy environments may be more uncomfortable for those with COPD.
However, individuals with COPD react differently to heat, and some may tolerate it better than others. This trial aims to understand these differences by observing how older adults with COPD respond to various indoor temperatures. Researchers will carefully monitor participants to ensure their safety throughout the study.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it explores how indoor temperatures affect people with COPD. Unlike traditional treatments like bronchodilators and corticosteroids, this trial investigates whether simply adjusting the indoor temperature can impact COPD symptoms. By simulating an indoor environment at different temperatures, researchers hope to understand how heat affects COPD patients, especially during heat events. This could lead to new, non-drug strategies for managing COPD symptoms, offering a fresh perspective on patient care.
What evidence suggests that this trial's simulated indoor thermal environments could be effective for understanding COPD responses to heat?
Research has shown that rising indoor temperatures can worsen symptoms of COPD, a lung disease that makes breathing difficult. One study found that a 10-degree increase in temperature can make COPD symptoms more severe. Additional research indicates that warm indoor conditions can affect cognitive function, potentially impacting those with COPD. This trial will compare two indoor temperature conditions: one group will experience an environment maintained at the recommended indoor temperature limit of 26 °C, while another group will be exposed to indoor overheating conditions at 36 °C. These findings suggest that controlling indoor temperatures could help manage COPD symptoms.24678
Who Is on the Research Team?
Glen P Kenny, PhD
Principal Investigator
University of Ottawa
Are You a Good Fit for This Trial?
This trial is for older adults diagnosed with chronic obstructive pulmonary disease (COPD). Participants should be able to spend a full day sitting indoors and must not have other major health issues that would make participation unsafe.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants are exposed to two different indoor environments for eight hours on separate days, at least one week apart, to measure physiological responses to heat.
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- Simulated indoor thermal environment
Trial Overview
The study compares how people with COPD respond to spending eight hours in two different indoor temperatures: one at the recommended safe limit (26°C) and another at a higher temperature. Each participant experiences both conditions on separate days, with close monitoring throughout.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Eight-hour passive seated exposure to an indoor environment maintained at 36 °C and 45% relative humidity, representing warm indoor conditions recorded inside Canadian dwellings without mechanical cooling during heat events.
Eight-hour passive seated exposure to an indoor environment maintained at 26 °C and 45% relative humidity, corresponding to the recommended upper indoor temperature limit for heat-susceptible occupants.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Ottawa
Lead Sponsor
Citations
1.
qa-1.test.yourcareeverywhere.com
qa-1.test.yourcareeverywhere.com/health-research/health-insights/asthma--allergy-and-copd-care-insights/when-indoor-temperature-rises--copd-symptoms-worsen.htmlWhen Indoor Temperature Rises, COPD Symptoms Worsen
A 10-degree increase in temperature in a home at the 75th percentile of particulate levels caused severe symptoms, compared to only a mild ...
The effects of indoor thermal environment on cognitive and ...
This study investigates the impact of indoor thermal conditions, typical of Sydney office buildings, on cognitive and office work performance,
The Impact of Thermal Water in Asthma and COPD
Asthma patients exposed to water aerosols exhibited improved lung function and reduced airway inflammation. Non-RCTs showed improved lung ...
Passive Heat Therapy for People With COPD
The investigators will test if heating can mimic the health benefits of exercise by monitoring the increase in leg blood-flow using ultrasound ...
5.
researchgate.net
researchgate.net/publication/319995875_Prediction_Of_Indoor_Conditions_And_Thermal_Comfort_Using_CFD_Simulations_A_Case_Study_Based_On_Experimental_DataPrediction Of Indoor Conditions And Thermal Comfort ...
The model was validated with experimental results, which showed an over-prediction of temperature (8.5%) and humidity (21.4%).
6.
researchgate.net
researchgate.net/publication/287507751_The_effect_of_high_indoor_temperatures_on_self-perceived_health_of_elderly_personsThe effect of high indoor temperatures on self-perceived ...
The second cohort of 29.8 % reported a mean temperature of 26.3 (±0.3) • C and "It is okay" to handle the heat, while the third group of 11.2 % reported a mean ...
7.
researchgate.net
researchgate.net/publication/377360466_Indoor_thermal_environment_and_human_health_A_systematic_reviewIndoor thermal environment and human health
The included indoor thermal factors consisted of air temperature, humidity, and air movement, and the health outcomes were divided into three categories, namely ...
8.
researchgate.net
researchgate.net/publication/345572254_A_systematic_evaluation_of_indoor_overheating_interactions_with_outdoor_heat_conditionsA systematic evaluation of indoor overheating interactions ...
The results show that in most building configurations, outdoor extreme heatwaves are synchronised with indoor extreme overheating events.
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