Laughing Gas Cryoablation for Duodenal Adenomas

MD
Overseen ByMarta Davila, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: M.D. Anderson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

To learn how well nitrous oxide cryoballoon ablation, a procedure that uses extreme cold to destroy abnormal tissue, works in treating flat duodenal adenomas (abnormal growths in the small intestine) in people with FAP or Lynch syndrome (HNPCC).

Who Is on the Research Team?

MD

Marta Davila, MD

Principal Investigator

UT MD Anderson Cancer Center

Are You a Good Fit for This Trial?

This trial is for people with hereditary conditions like familial adenomatous polyposis (FAP) or Lynch syndrome who have flat duodenal adenomas (abnormal growths in the small intestine).

Inclusion Criteria

I have been diagnosed with FAP or HNPCC.
I am between 20 and 75 years old.
I have flat duodenal adenomas confirmed by biopsy.
See 1 more

Exclusion Criteria

Allergy or intolerance to components of the nitrous oxide cryoballoon system
Pregnancy
I have had surgery on my duodenum in the area being studied.
See 3 more

What Are the Treatments Tested in This Trial?

Interventions

  • Nitrous Oxide Cryoablation

Trial Overview

The study is testing nitrous oxide cryoballoon ablation, a procedure that uses very cold gas to freeze and destroy abnormal tissue during an endoscopy.

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: EGD + CBAExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials
3,107
Recruited
1,813,000+