Precision Nutrition for Obesity and Prediabetes Prevention
(PNOD Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This randomized controlled trial will evaluate the effectiveness of a culturally sensitive precision nutrition intervention for improving obesity- and diabetes-related outcomes among African American and Hispanic/Latino adults who are overweight, obese, or have prediabetes. Participants will be randomized to either a precision nutrition intervention group or a control group receiving standard nutrition counseling and educational materials. The intervention incorporates individualized dietary recommendations based on participant characteristics, including dietary habits, physical activity, socioeconomic factors, psychosocial factors, phenotype, and genotype. Outcomes will be assessed at baseline, 6 weeks, and 12 weeks and will include body weight, diet quality, fasting blood glucose, hemoglobin A1C, body composition, physical activity, blood pressure, and metabolic biomarkers. Feasibility, acceptability, and sustainability of the intervention will also be evaluated.
Who Is on the Research Team?
Janet Antwi, B.Pharm, M.S, Ph.D, RPh, RD,
Principal Investigator
Prairie View A&M University
Are You a Good Fit for This Trial?
This trial is for African American and Hispanic/Latino adults who are overweight, obese, or have prediabetes. Participants should be interested in improving their health through nutrition and lifestyle changes.Inclusion Criteria
Exclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Precision Nutrition Intervention
Trial Overview
The study compares a personalized nutrition program tailored to each person's habits, genetics, and lifestyle with standard nutrition counseling. Participants are randomly assigned to one of the two groups.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Active Control
Participants will receive a culturally sensitive precision nutrition intervention including individualized nutrition counseling, personalized meal planning, physical activity guidance, health behavior lessons, mobile-health support, motivational interviewing, and social support resources.
Participants will receive standard nutrition counseling and dietary education materials without individualized precision nutrition recommendations.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Prairie View A&M University
Lead Sponsor
United States Department of Agriculture (USDA)
Collaborator
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.